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Keyword

ABCC6

Description: ABCC6 is a human protein-coding gene that encodes a membrane transporter studied in drug transport and multidrug resistance.
Wikidata ID: wiki/Q14916171
OpenAlex ID: keywords/abcc6
Mutations in ABCC6 cause pseudoxanthoma elasticum
2000 · Arthur A.B. Bergen, Astrid S. Plomp, et al. · Nature Genetics · 593
Mutations in a gene encoding an ABC transporter cause pseudoxanthoma elasticum
2000 · Olivier Le Saux, Zsolt Urban, et al. · Nature Genetics · 540
ABCC6–Mediated ATP Secretion by the Liver Is the Main Source of the Mineralization Inhibitor Inorganic Pyrophosphate in the Systemic Circulation—Brief Report
2014 · Robert S. Jansen, Suzanne Duijst, et al. · Arteriosclerosis Thrombosis and Vascular Biology · 304
ABCC Drug Efflux Pumps and Organic Anion Uptake Transporters in Human Gliomas and the Blood-Tumor Barrier
2005 · Holger Bronger, Jörg König, et al. · Cancer Research · 296
ABCC6 prevents ectopic mineralization seen in pseudoxanthoma elasticum by inducing cellular nucleotide release
2013 · Robert S. Jansen, Aslı Küçükosmanoğlu, et al. · Proceedings of the National Academy of Sciences · 265
Characterization of the drug resistance and transport properties of multidrug resistance protein 6 (MRP6, ABCC6).
2002 · Martin G Belinsky, Zhe-Sheng Chen, et al. · PubMed · 262
Loss of ATP-dependent Transport Activity in Pseudoxanthoma Elasticum-associated Mutants of Human ABCC6 (MRP6)
2002 · Attila Iliás, Zsolt Urbán, et al. · Journal of Biological Chemistry · 240
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Mammalian multidrug-resistance proteins (MRPs)
2011 · Andrew J. Slot, Steven V. Molinski, et al. · Essays in Biochemistry · 218
Disruption of Abcc6 in the mouse: novel insight in the pathogenesis of pseudoxanthoma elasticum
2005 · Theo G.M.F. Gorgels, Xiaofeng Hu, et al. · Human Molecular Genetics · 207
ID4 Imparts Chemoresistance and Cancer Stemness to Glioma Cells by Derepressing miR-9*–Mediated Suppression of SOX2
2011 · Hye-Min Jeon, Young-Woo Sohn, et al. · Cancer Research · 206
Targeted Ablation of the Abcc6 Gene Results in Ectopic Mineralization of Connective Tissues
2005 · John F. Klement, Yasushi Matsuzaki, et al. · Molecular and Cellular Biology · 205
MRP6 (ABCC6) Detection in Normal Human Tissues and Tumors
2002 · George L Scheffer, Xiaofeng Hu, et al. · Laboratory Investigation · 204
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A Spectrum of ABCC6 Mutations Is Responsible for Pseudoxanthoma Elasticum
2001 · Olivier Le Saux, Konstanze Beck, et al. · The American Journal of Human Genetics · 201
Pseudoxanthoma Elasticum-Like Phenotype with Cutis Laxa and Multiple Coagulation Factor Deficiency Represents a Separate Genetic Entity
2006 · Olivier M. Vanakker, Ludovic Martin, et al. · Journal of Investigative Dermatology · 198
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Pseudoxanthoma elasticum: clinical phenotypes, molecular genetics and putative pathomechanisms
2008 · Qiaoli Li, Qiujie Jiang, et al. · Experimental Dermatology · 176
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Genetics in Arterial Calcification
2011 · Frank Rutsch, Yvonne Nitschke, et al. · Circulation Research · 172
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Male-Biased Autosomal Effect of 16p13.11 Copy Number Variation in Neurodevelopmental Disorders
2013 · Maria Tropeano, Joo Wook Ahn, et al. · PLoS ONE · 153
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Pseudoxanthoma Elasticum: Molecular Genetics and Putative Pathomechanisms
2009 · Jouni Uitto, Qiaoli Li, et al. · Journal of Investigative Dermatology · 147
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An update on the ocular phenotype in patients with pseudoxanthoma elasticum
2013 · Martin Gliem, Julie De Zaeytijd, et al. · Frontiers in Genetics · 144
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Identification of Abcc6 as the major causal gene for dystrophic cardiac calcification in mice through integrative genomics
2007 · Haijin Meng, Iset Vera, et al. · Proceedings of the National Academy of Sciences · 134
Distribution and functional activity of P-glycoprotein and multidrug resistance-associated proteins in human brain microvascular endothelial cells in hippocampal sclerosis
2005 · Hisashi Kubota, Hideyuki Ishihara, et al. · Epilepsy Research · 128
Oct4 is a critical regulator of stemness in head and neck squamous carcinoma cells
2014 · B S Koo, S H Lee, et al. · Oncogene · 126
Oral administration of pyrophosphate inhibits connective tissue calcification
2017 · Dóra Dedinszki, Flóra Szeri, et al. · EMBO Molecular Medicine · 119
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Kaempferol enhances cisplatin's effect on ovarian cancer cells through promoting apoptosis caused by down regulation of cMyc
2010 · Haitao Luo, Matthew K Daddysman, et al. · Cancer Cell International · 119
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Vascular pathology of medial arterial calcifications in NT5E deficiency: Implications for the role of adenosine in pseudoxanthoma elasticum
2011 · Thomas C. Markello, Laura K. Pak, et al. · Molecular Genetics and Metabolism · 116
Works count: 562
Citation count: 12,650
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