Keyword

ABCG1

Description: ABCG1 is a human protein-coding gene that encodes a transporter involved in cellular cholesterol and lipid transport.

Primary topic: Cholesterol and Lipid Metabolism (49%)

Wikidata ID: wiki/Q18034442

OpenAlex ID: keywords/abcg1

ATP-binding cassette transporters G1 and G4 mediate cellular cholesterol efflux to high-density lipoproteins

2004 · Nan Wang, Debin Lan, et al. · Proceedings of the National Academy of Sciences · 1,061

Synthetic LXR ligand inhibits the development of atherosclerosis in mice

2002 · Sean B. Joseph, Elaine McKilligin, et al. · Proceedings of the National Academy of Sciences · 948

ABCG1 has a critical role in mediating cholesterol efflux to HDL and preventing cellular lipid accumulation

2005 · Matthew A. Kennedy, Gabriel C. Barrera, et al. · Cell Metabolism · 884

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Dysfunctional HDL and atherosclerotic cardiovascular disease

2015 · Robert S. Rosenson, H. Bryan Brewer, et al. · Nature Reviews Cardiology · 820

Foam cells in atherosclerosis

2013 · Xiao-Hua Yu, Yu-Chang Fu, et al. · Clinica Chimica Acta · 771

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Mechanisms of foam cell formation in atherosclerosis

2017 · Dimitry A. Chistiakov, Alexandra A. Melnichenko, et al. · Journal of Molecular Medicine · 745

Oxidized Low-Density Lipoprotein Induces Long-Term Proinflammatory Cytokine Production and Foam Cell Formation via Epigenetic Reprogramming of Monocytes

2014 · Siroon Bekkering, Jessica Quintin, et al. · Arteriosclerosis Thrombosis and Vascular Biology · 731

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ATP-Binding Cassette Transporters and HDL Suppress Hematopoietic Stem Cell Proliferation

2010 · Laurent Yvan-Charvet, Tamara Pagler, et al. · Science · 725

LXR Signaling Couples Sterol Metabolism to Proliferation in the Acquired Immune Response

2008 · Steven J. Bensinger, Michelle N. Bradley, et al. · Cell · 712

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LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes

2001 · Bryan A. Laffitte, Joyce J. Repa, et al. · Proceedings of the National Academy of Sciences · 683

Role of HDL, ABCA1, and ABCG1 Transporters in Cholesterol Efflux and Immune Responses

2009 · Laurent Yvan-Charvet, Nan Wang, et al. · Arteriosclerosis Thrombosis and Vascular Biology · 681

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Altered renal lipid metabolism and renal lipid accumulation in human diabetic nephropathy

2013 · Michal Herman-Edelstein, Pnina Scherzer, et al. · Journal of Lipid Research · 647

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The role of reverse cholesterol transport in animals and humans and relationship to atherosclerosis

2008 · Daniel J. Rader, Eric T. Alexander, et al. · Journal of Lipid Research · 597

Macrophage ABCA1 and ABCG1, but not SR-BI, promote macrophage reverse cholesterol transport in vivo

2007 · Xun Wang, Heidi L. Collins, et al. · Journal of Clinical Investigation · 593

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Differential inhibition of macrophage foam-cell formation and atherosclerosis in mice by PPARα, β/δ, and γ

2004 · Andrew C. Li, Christoph J. Binder, et al. · Journal of Clinical Investigation · 573

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27-Hydroxycholesterol Is an Endogenous Ligand for Liver X Receptor in Cholesterol-loaded Cells

2001 · Xuan Fu, John G. Menke, et al. · Journal of Biological Chemistry · 572

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miR-33 links SREBP-2 induction to repression of sterol transporters

2010 · Tyler J. Marquart, Ryan M. Allen, et al. · Proceedings of the National Academy of Sciences · 562

Molecular Mechanisms of Cellular Cholesterol Efflux

2014 · Michael C. Phillips · Journal of Biological Chemistry · 545

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ABCG1 (ABC8), the human homolog of the Drosophila white gene, is a regulator of macrophage cholesterol and phospholipid transport

2000 · Jochen Klucken, Christa Büchler, et al. · Proceedings of the National Academy of Sciences · 543

HDL, ABC Transporters, and Cholesterol Efflux: Implications for the Treatment of Atherosclerosis

2008 · Alan R. Tall, Laurent Yvan-Charvet, et al. · Cell Metabolism · 539

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Combined deficiency of ABCA1 and ABCG1 promotes foam cell accumulation and accelerates atherosclerosis in mice

2007 · Laurent Yvan-Charvet, Mollie Ranalletta, et al. · Journal of Clinical Investigation · 537

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ApoE regulates hematopoietic stem cell proliferation, monocytosis, and monocyte accumulation in atherosclerotic lesions in mice

2011 · Andrew J. Murphy, Mani Akhtari, et al. · Journal of Clinical Investigation · 522

Macrophage‐mediated cholesterol handling in atherosclerosis

2015 · Dimitry A. Chistiakov, Yuri V. Bobryshev, et al. · Journal of Cellular and Molecular Medicine · 511

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ABCG5 and ABCG8 Are Obligate Heterodimers for Protein Trafficking and Biliary Cholesterol Excretion

2003 · Gregory A. Graf, Liqing Yu, et al. · Journal of Biological Chemistry · 475

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Increased Inflammatory Gene Expression in ABC Transporter–Deficient Macrophages

2008 · Laurent Yvan-Charvet, Carrie Welch, et al. · Circulation · 457

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Works count: 2,984

Citation count: 95,430