Keyword

ABCG2

Description: A human gene encoding an ATP-binding cassette transporter that exports diverse molecules and contributes to cellular drug resistance.

Primary topic: Drug Transport and Resistance Mechanisms (49%)

Wikidata ID: wiki/Q4650095

OpenAlex ID: keywords/abcg2

A multidrug resistance transporter from human MCF-7 breast cancer cells

1998 · L. Austin Doyle, Weidong Yang, et al. · Proceedings of the National Academy of Sciences · 2,323

The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype

2001 · Sheng Zhou, John D. Schuetz, et al. · Nature Medicine · 2,281

Revisiting the role of ABC transporters in multidrug-resistant cancer

2018 · Robert W. Robey, Kristen M. Pluchino, et al. · Nature reviews. Cancer · 1,855

Multidrug resistance proteins: role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense

2004 · Elaine M. Leslie, Roger G. Deeley, et al. · Toxicology and Applied Pharmacology · 1,406

Gout

2021 · Nicola Dalbeth, Anna L Gosling, et al. · The Lancet · 1,350

Identification and Characterization of Ovarian Cancer-Initiating Cells from Primary Human Tumors

2008 · Shu Zhang, Curt Balch, et al. · Cancer Research · 1,295

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A distinct “side population” of cells with high drug efflux capacity in human tumor cells

2004 · C. Hirschmann-Jax, A. E. Foster, et al. · Proceedings of the National Academy of Sciences · 1,281

Modulation of Genetic Associations with Serum Urate Levels by Body-Mass-Index in Humans

2015 · Jennifer E. Huffman, Eva Albrecht, et al. · PLoS ONE · 1,227

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Subcellular localization and distribution of the breast cancer resistance protein transporter in normal human tissues.

2001 · M Maliepaard, G L Scheffer, et al. · PubMed · 1,129

Immunophenotype of Human Adipose-Derived Cells: Temporal Changes in Stromal-Associated and Stem Cell–Associated Markers

2005 · James B. Mitchell, Kevin McIntosh, et al. · Stem Cells · 1,125

Multidrug resistance mediated by the breast cancer resistance protein BCRP (ABCG2)

2003 · L Austin Doyle, Douglas D Ross · Oncogene · 1,052

ABC Multidrug Transporters: Structure, Function and Role in Chemoresistance

2007 · Frances J Sharom · Pharmacogenomics · 974

Side Population in Human Lung Cancer Cell Lines and Tumors Is Enriched with Stem-like Cancer Cells

2007 · Maria M. Ho, Alvin V. Ng, et al. · Cancer Research · 948

Side Population Is Enriched in Tumorigenic, Stem-Like Cancer Cells, whereas ABCG2+ and ABCG2− Cancer Cells Are Similarly Tumorigenic

2005 · Lubna Patrawala, Tammy Calhoun, et al. · Cancer Research · 904

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Quantitative targeted absolute proteomics of human blood–brain barrier transporters and receptors

2011 · Yasuo Uchida, Sumio Ohtsuki, et al. · Journal of Neurochemistry · 881

Blood-brain barrier active efflux transporters: ATP-binding cassette gene family

2004 · Wolfgang Löscher, Heidrun Potschka · NeuroRx · 872

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The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria

2002 · Johan W. Jonker, Marije Buitelaar, et al. · Proceedings of the National Academy of Sciences · 821

The Role of ABC Transporters in Clinical Practice

2003 · Gregory D. Leonard, Tito Fojo, et al. · The Oncologist · 818

PTEN/PI3K/Akt Pathway Regulates the Side Population Phenotype and ABCG2 Activity in Glioma Tumor Stem-like Cells

2009 · Anne-Marie Bleau, Dolores Hambardzumyan, et al. · Cell stem cell · 808

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A fast and high-quality charge model for the next generation general AMBER force field

2020 · Xibing He, Viet H. Man, et al. · The Journal of Chemical Physics · 789

The ABCG2 transporter is an efficient Hoechst 33342 efflux pump and is preferentially expressed by immature human hematopoietic progenitors

2002 · Christian W. Scharenberg, Michael A. Harkey, et al. · Blood · 770

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Highly tumorigenic lung cancer CD133 + cells display stem-like features and are spared by cisplatin treatment

2009 · Giulia Bertolini, Luca Roz, et al. · Proceedings of the National Academy of Sciences · 767

Mammalian drug efflux transporters of the ATP binding cassette (ABC) family in multidrug resistance: A review of the past decade

2015 · Zhaolin Chen, Tianlu Shi, et al. · Cancer Letters · 730

Human Multidrug Resistance ABCB and ABCG Transporters: Participation in a Chemoimmunity Defense System

2006 · Balázs Sarkadi, László Homolya, et al. · Physiological Reviews · 728

Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study

2008 · Abbas Dehghan, Anna Köttgen, et al. · The Lancet · 718

Works count: 13,090

Citation count: 364,100