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ACE2
Description:
ACE2 may refer to angiotensin-converting enzyme 2, a protein involved in viral entry and physiology, or to an insect acetylcholinesterase gene.
Primary topic:
SARS-CoV-2 and COVID-19 Research (33%)
Related topics:
SARS-CoV-2 and COVID-19 Research (33%),
Renin-Angiotensin System Studies (16%),
COVID-19 Clinical Research Studies (11%)
OpenAlex ID:
keywords/ace2
SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
2020
·
Markus Hoffmann
, Hannah Kleine-Weber
, et al.
·
Cell
·
20,265
PDF
Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor
2020
·
Jun Lan
, Jiwan Ge
, et al.
·
Nature
·
6,109
PDF
Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2
2020
·
Renhong Yan
, Yuanyuan Zhang
, et al.
·
Science
·
5,043
Structural basis of receptor recognition by SARS-CoV-2
2020
·
Jian Shang
, Gang Ye
, et al.
·
Nature
·
3,655
PDF
A Novel Angiotensin-Converting Enzyme–Related Carboxypeptidase (ACE2) Converts Angiotensin I to Angiotensin 1-9
2000
·
Mary Donoghue
, Frank Hsieh
, et al.
·
Circulation Research
·
3,085
PDF
Structural and Functional Basis of SARS-CoV-2 Entry by Using Human ACE2
2020
·
Qihui Wang
, Yanfang Zhang
, et al.
·
Cell
·
2,867
PDF
Angiotensin-converting enzyme 2 (ACE2) as a SARS-CoV-2 receptor: molecular mechanisms and potential therapeutic target
2020
·
Haibo Zhang
, Josef M. Penninger
, et al.
·
Intensive Care Medicine
·
2,685
PDF
SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes
2020
·
HCA Lung Biological Network
, Waradon Sungnak
, et al.
·
Nature Medicine
·
2,490
PDF
SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues
2020
·
Carly G.K. Ziegler
, Samuel J. Allon
, et al.
·
Cell
·
2,284
Renin–Angiotensin–Aldosterone System Inhibitors in Patients with Covid-19
2020
·
Muthiah Vaduganathan
, Orly Vardeny
, et al.
·
New England Journal of Medicine
·
2,100
PDF
Structure of SARS Coronavirus Spike Receptor-Binding Domain Complexed with Receptor
2005
·
Fang Li
, Wenhui Li
, et al.
·
Science
·
2,030
Neuropilin-1 facilitates SARS-CoV-2 cell entry and infectivity
2020
·
Ludovico Cantuti-Castelvetri
, Ravi Ojha
, et al.
·
Science
·
1,920
PDF
Angiotensin-converting enzyme 2 is an essential regulator of heart function
2002
·
Michael A. Crackower
, Renu Sarao
, et al.
·
Nature
·
1,734
Human neutralizing antibodies elicited by SARS-CoV-2 infection
2020
·
Bin Ju
, Qi Zhang
, et al.
·
Nature
·
1,666
PDF
Expression of the SARS-CoV-2 cell receptor gene ACE2 in a wide variety of human tissues
2020
·
Meng-Yuan Li
, Lin Li
, et al.
·
Infectious Diseases of Poverty
·
1,589
PDF
Alterations in Gut Microbiota of Patients With COVID-19 During Time of Hospitalization
2020
·
Tao Zuo
, Fen Zhang
, et al.
·
Gastroenterology
·
1,536
COVID-19 and the cardiovascular system: implications for risk assessment, diagnosis, and treatment options
2020
·
Tomasz J Guzik
, Saidi A Mohiddin
, et al.
·
Cardiovascular Research
·
1,440
PDF
Hydrolysis of Biological Peptides by Human Angiotensin-converting Enzyme-related Carboxypeptidase
2002
·
Chad Vickers
, Paul Hales
, et al.
·
Journal of Biological Chemistry
·
1,407
PDF
A human neutralizing antibody targets the receptor-binding site of SARS-CoV-2
2020
·
Rui Shi
, Chao Shan
, et al.
·
Nature
·
1,286
PDF
ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation
2012
·
Tatsuo Hashimoto
, Thomas Perlot
, et al.
·
Nature
·
1,269
PDF
Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia
2020
·
David H. Brann
, Tatsuya Tsukahara
, et al.
·
Science Advances
·
1,197
PDF
The ACE2 expression in human heart indicates new potential mechanism of heart injury among patients infected with SARS-CoV-2
2020
·
Liang Chen
, Xiangjie Li
, et al.
·
Cardiovascular Research
·
1,165
PDF
Transplantation of ACE2- Mesenchymal Stem Cells Improves the Outcome of Patients with COVID-19 Pneumonia
2020
·
Zikuan Leng
, Rongjia Zhu
, et al.
·
Aging and Disease
·
1,147
PDF
The ACE2/Angiotensin-(1–7)/MAS Axis of the Renin-Angiotensin System: Focus on Angiotensin-(1–7)
2017
·
Robson Augusto Souza Santos
, Walkyria Oliveira Sampaio
, et al.
·
Physiological Reviews
·
1,141
SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2
2020
·
Thomas Mandel Clausen
, Daniel R. Sandoval
, et al.
·
Cell
·
1,137
PDF
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Works count:
12,160
Citation count:
371,700
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