Get started
Keyword

acid-sensing ion channels

Description: Membrane proteins that open in response to extracellular acidity, allowing ions to cross cell membranes and influencing physiological signaling.
Wikidata ID: wiki/Q4222244
OpenAlex ID: keywords/acid-sensing-ion-channels
A proton-gated cation channel involved in acid-sensing
1997 · Rainer Waldmann, Guy Champigny, et al. · Nature · 1,347
Neuroprotection in Ischemia
2004 · Zhi-Gang Xiong, Xiao-Man Zhu, et al. · Cell · 1,025
PDF
The Acid-Activated Ion Channel ASIC Contributes to Synaptic Plasticity, Learning, and Memory
2002 · John A. Wemmie, Jianguo Chen, et al. · Neuron · 657
PDF
Acid-sensing ion channels in pain and disease
2013 · John A. Wemmie, Rebecca J. Taugher, et al. · Nature reviews. Neuroscience · 607
Diclofenac: an update on its mechanism of action and safety profile
2010 · Tong J. Gan · Current Medical Research and Opinion · 593
Acid-sensing ion channels: advances, questions and therapeutic opportunities
2006 · John A. Wemmie, Margaret P. Price, et al. · Trends in Neurosciences · 559
pH sensing and regulation in cancer
2013 · Mehdi Damaghi, Jonathan W. Wojtkowiak, et al. · Frontiers in Physiology · 536
PDF
Nonsteroid Anti-Inflammatory Drugs Inhibit Both the Activity and the Inflammation-Induced Expression of Acid-Sensing Ion Channels in Nociceptors
2001 · Nicolas Voilley, Jan de Weille, et al. · Journal of Neuroscience · 528
A Modulatory Subunit of Acid Sensing Ion Channels in Brain and Dorsal Root Ganglion Cells
1997 · Eric Lingueglia, Jan. R. de Weille, et al. · Journal of Biological Chemistry · 502
PDF
H+-gated cation channels: neuronal acid sensors in the NaC/DEG family of ion channels
1998 · Rainer Waldmann, Michel Lazdunski · Current Opinion in Neurobiology · 501
Isolation of a Tarantula Toxin Specific for a Class of Proton-gated Na+ Channels
2000 · Pierre Escoubas, Jan R. De Weille, et al. · Journal of Biological Chemistry · 475
PDF
Pore architecture and ion sites in acid-sensing ion channels and P2X receptors
2009 · Eric B. Gonzales, Toshimitsu Kawate, et al. · Nature · 456
A sensory neuron-specific, proton-gated ion channel
1998 · Chih-Cheng Chen, Steven England, et al. · Proceedings of the National Academy of Sciences · 446
The Amygdala Is a Chemosensor that Detects Carbon Dioxide and Acidosis to Elicit Fear Behavior
2009 · Adam E. Ziemann, Jason E. Allen, et al. · Cell · 434
PDF
Chronic hyperalgesia induced by repeated acid injections in muscle is abolished by the loss of ASIC3, but not ASIC1
2003 · Kathleen A Sluka, Margaret P Price, et al. · Pain · 433
The ASICs: Signaling molecules? Modulators?
2003 · Oleg Krishtal · Trends in Neurosciences · 418
ASIC3, a sensor of acidic and primary inflammatory pain
2008 · Emmanuel Deval, Jacques Noël, et al. · The EMBO Journal · 405
Black mamba venom peptides target acid-sensing ion channels to abolish pain
2012 · Sylvie Diochot, Anne Baron, et al. · Nature · 402
PDF
Lactate enhances the acid-sensing Na+ channel on ischemia-sensing neurons
2001 · D. C. Immke, E. W. McCleskey · Nature Neuroscience · 386
A new sea anemone peptide, APETx2, inhibits ASIC3, a major acid‐sensitive channel in sensory neurons
2004 · Sylvie Diochot, Anne Baron, et al. · The EMBO Journal · 374
Seizure termination by acidosis depends on ASIC1a
2008 · Adam E Ziemann, Mikael K Schnizler, et al. · Nature Neuroscience · 365
Extracellular pH Regulates Bone Cell Function , ,
2008 · Timothy R. Arnett · Journal of Nutrition · 347
PDF
A heteromeric Texas coral snake toxin targets acid-sensing ion channels to produce pain
2011 · Christopher J. Bohlen, Alexander T. Chesler, et al. · Nature · 336
ProInflammatory Mediators, Stimulators of Sensory Neuron Excitability via the Expression of Acid-Sensing Ion Channels
2002 · Julien Mamet, Anne Baron, et al. · Journal of Neuroscience · 336
PDF
Acid-Sensing Ion Channels (ASICs): Pharmacology and implication in pain
2010 · Emmanuel Deval, Xavier Gasull, et al. · Pharmacology & Therapeutics · 325
Works count: 2,326
Citation count: 65,350
Year
Topic
Type