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Keyword

ACSL5

Description: ACSL5 is a human protein-coding gene that encodes an enzyme involved in activating long-chain fatty acids for lipid metabolism.
Wikidata ID: wiki/Q18040521
OpenAlex ID: keywords/acsl5
ACSL family: The regulatory mechanisms and therapeutic implications in cancer
2021 · Jing Quan, Ann M. Bode, et al. · European Journal of Pharmacology · 306
Ceramide Is Metabolized to Acylceramide and Stored in Lipid Droplets
2017 · Can E. Senkal, Mohamed F. Salama, et al. · Cell Metabolism · 238
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Systematic Analysis of Gene Expression Alterations and Clinical Outcomes for Long-Chain Acyl-Coenzyme A Synthetase Family in Cancer
2016 · Wei-Ching Chen, Chih-Yang Wang, et al. · PLoS ONE · 169
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Revised nomenclature for the mammalian long-chain acyl-CoA synthetase gene family
2004 · Douglas G. Mashek, Karin E. Bornfeldt, et al. · Journal of Lipid Research · 165
Hepatic long-chain acyl-CoA synthetase 5 mediates fatty acid channeling between anabolic and catabolic pathways
2010 · So Young Bu, Douglas G. Mashek · Journal of Lipid Research · 136
Rat Long Chain Acyl-CoA Synthetase 5 Increases Fatty Acid Uptake and Partitioning to Cellular Triacylglycerol in McArdle-RH7777 Cells
2005 · Douglas G. Mashek, Michelle A. McKenzie, et al. · Journal of Biological Chemistry · 129
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Fatty acid metabolism pathway play an important role in carcinogenesis of human colorectal cancers by Microarray-Bioinformatics analysis
2005 · Ching-Sheng Yeh, Jaw-Yuan Wang, et al. · Cancer Letters · 128
p53-Defective Tumors With a Functional Apoptosome-Mediated Pathway: A New Therapeutic Target
2005 · Tetsuo Mashima, Tomoko Oh-hara, et al. · JNCI Journal of the National Cancer Institute · 114
Cytoplasmic SIRT6-mediated ACSL5 deacetylation impedes nonalcoholic fatty liver disease by facilitating hepatic fatty acid oxidation
2022 · Tianyun Hou, Yuan Tian, et al. · Molecular Cell · 103
Acyl CoA synthetase 5 (ACSL5) ablation in mice increases energy expenditure and insulin sensitivity and delays fat absorption
2016 · Thomas A. Bowman, Kayleigh R. O'Keeffe, et al. · Molecular Metabolism · 99
Hypoxia-responsive PPARGC1A/BAMBI/ACSL5 axis promotes progression and resistance to lenvatinib in hepatocellular carcinoma
2023 · Qiangnu Zhang, Lingfeng Xiong, et al. · Oncogene · 96
Genome-wide meta-analysis identifies novel loci associated with age-related macular degeneration
2020 · Xikun Han, Puya Gharahkhani, et al. · Journal of Human Genetics · 92
Acyl‐CoA synthetase as a cancer survival factor: its inhibition enhances the efficacy of etoposide
2009 · Tetsuo Mashima, Shigeo Sato, et al. · Cancer Science · 89
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The type 2 diabetes presumed causal variant within TCF7L2 resides in an element that controls the expression of ACSL5
2016 · Qianghua Xia, Alessandra Chesi, et al. · Diabetologia · 81
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Real-Time Tracking of BODIPY-C12 Long-Chain Fatty Acid in Human Term Placenta Reveals Unique Lipid Dynamics in Cytotrophoblast Cells
2016 · Kevin Kolahi, Samantha Louey, et al. · PLoS ONE · 80
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Fatty acid transport and activation and the expression patterns of genes involved in fatty acid trafficking
2008 · Angel Sandoval, Peter Fraisl, et al. · Archives of Biochemistry and Biophysics · 74
Dietary elaidic acid boosts tumoral antigen presentation and cancer immunity via ACSL5
2024 · Yongfeng Lai, Yuan Gao, et al. · Cell Metabolism · 72
TNF-α induces acyl-CoA synthetase 3 to promote lipid droplet formation in human endothelial cells
2019 · Hye Seung Jung, Masami Shimizu-Albergine, et al. · Journal of Lipid Research · 66
Role of ACSL5 in fatty acid metabolism
2023 · Qin Luo, Avash Das, et al. · Heliyon · 63
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Differential expression and prognostic role of selected genes in colorectal cancer patients.
2013 · Pavel Pitule, Ondrej Vycital, et al. · PubMed · 63
Sirtuin 6—A Key Regulator of Hepatic Lipid Metabolism and Liver Health
2023 · X. Charlie Dong · Cells · 61
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A multi-ethnic meta-analysis identifies novel genes, including ACSL5, associated with amyotrophic lateral sclerosis
2020 · Ryoichi Nakamura, Kazuharu Misawa, et al. · Communications Biology · 61
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Genome-wide Meta-analysis Finds the ACSL5-ZDHHC6 Locus Is Associated with ALS and Links Weight Loss to the Disease Genetics
2020 · Alfredo Iacoangeli, Tian Lin, et al. · Cell Reports · 59
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Transcriptional Activation of Hepatic ACSL3 and ACSL5 by Oncostatin M Reduces Hypertriglyceridemia Through Enhanced β-Oxidation
2007 · Yue Zhou, Parveen Abidi, et al. · Arteriosclerosis Thrombosis and Vascular Biology · 59
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Peroxisome Proliferator‐activated Receptor γ 2 and Acyl‐CoA Synthetase 5 Polymorphisms Influence Diet Response
2007 · Kristi B. Adamo, Robert Dent, et al. · Obesity · 58
Works count: 246
Citation count: 4,105
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