Keyword

ADAR2

Description: An RNA-editing enzyme encoded by the human ADARB1 gene that converts adenosine to inosine in RNA molecules.

Primary topic: RNA regulation and disease (76%)

Related topic: RNA regulation and disease (76%)

Wikidata ID: wiki/Q17709587

OpenAlex ID: keywords/adar2

RNA editing with CRISPR-Cas13

2017 · David B. T. Cox, Jonathan S. Gootenberg, et al. · Science · 1,812

Point mutation in an AMPA receptor gene rescues lethality in mice deficient in the RNA-editing enzyme ADAR2

2000 · Miyoko Higuchi, Stefan Maas, et al. · Nature · 967

Modulation of microRNA processing and expression through RNA editing by ADAR deaminases

2005 · Weidong Yang, Thimmaiah P Chendrimada, et al. · Nature Structural & Molecular Biology · 788

Regulation of alternative splicing by RNA editing

1999 · Susan M. Rueter, T. Renee Dawson, et al. · Nature · 637

Dynamic landscape and regulation of RNA editing in mammals

2017 · Meng How Tan, Qin Li, et al. · Nature · 627

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A cytosine deaminase for programmable single-base RNA editing

2019 · Omar O. Abudayyeh, Jonathan S. Gootenberg, et al. · Science · 462

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Inositol Hexakisphosphate Is Bound in the ADAR2 Core and Required for RNA Editing

2005 · Mark R. Macbeth, Heidi L. Schubert, et al. · Science · 432

Underediting of glutamate receptor GluR-B mRNA in malignant gliomas

2001 · Stefan Maas, Stephan Patt, et al. · Proceedings of the National Academy of Sciences · 382

Predicting sites of ADAR editing in double-stranded RNA

2011 · Julie M. Eggington, Tom Greene, et al. · Nature Communications · 372

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Adenosine deaminases acting on RNA (ADARs) are both antiviral and proviral

2011 · Charles E. Samuel · Virology · 315

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Double-Stranded RNA Adenosine Deaminases ADAR1 and ADAR2 Have Overlapping Specificities

2000 · Katrina A. Lehmann, Brenda L. Bass · Biochemistry · 282

Programmable RNA editing by recruiting endogenous ADAR using engineered RNAs

2019 · Liang Qu, Zongyi Yi, et al. · Nature Biotechnology · 277

Dynamic association of RNA-editing enzymes with the nucleolus

2003 · Joana M. P. Desterro, Liam P. Keegan, et al. · Journal of Cell Science · 268

The Solution Structure of the ADAR2 dsRBM-RNA Complex Reveals a Sequence-Specific Readout of the Minor Groove

2010 · Richard Stefl, Florian C. Oberstrass, et al. · Cell · 240

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A disrupted RNA editing balance mediated by ADARs (Adenosine DeAminases that act on RNA) in human hepatocellular carcinoma

2013 · Tim Hon Man Chan, Chi Ho Lin, et al. · Gut · 237

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Substrate recognition by ADAR1 and ADAR2

2001 · SWEE KEE WONG, SHUJI SATO, et al. · RNA · 237

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ADAR2-mediated editing of RNA substrates in the nucleolus is inhibited by C/D small nucleolar RNAs

2005 · Patrice Vitali, Eugenia Basyuk, et al. · The Journal of Cell Biology · 235

Structures of human ADAR2 bound to dsRNA reveal base-flipping mechanism and basis for site selectivity

2016 · Melissa M Matthews, Justin M Thomas, et al. · Nature Structural & Molecular Biology · 232

ADAR2-Dependent RNA Editing of AMPA Receptor Subunit GluR2 Determines Vulnerability of Neurons in Forebrain Ischemia

2006 · Peter L. Peng, Xiafen Zhong, et al. · Neuron · 231

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The essential role of AMPA receptor GluR2 subunit RNA editing in the normal and diseased brain

2012 · Amanda Wright, Bryce Vissel · Frontiers in Molecular Neuroscience · 213

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Requirement of Dimerization for RNA Editing Activity of Adenosine Deaminases Acting on RNA

2003 · Dan-Sung C. Cho, Weidong Yang, et al. · Journal of Biological Chemistry · 195

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Editing modifies the GABAA receptor subunit 3

2007 · J. Ohlson, J. S. Pedersen, et al. · RNA · 194

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Replicating hepatitis delta virus RNA is edited in the nucleus by the small form of ADAR1

2002 · Swee Kee Wong, David W. Lazinski · Proceedings of the National Academy of Sciences · 193

dADAR, a Drosophila double-stranded RNA-specific adenosine deaminase is highly developmentally regulated and is itself a target for RNA editing

2000 · MICHAEL J. PALLADINO, LIAM P. KEEGAN, et al. · RNA · 192

Editing independent effects of ADARs on the miRNA/siRNA pathways

2009 · Bret S E Heale, Liam P Keegan, et al. · The EMBO Journal · 190

Works count: 796

Citation count: 26,710