Keyword

ADAR3

Description: A gene encoding an RNA-editing enzyme in the adenosine deaminase acting on RNA family, studied in molecular biology and neuroscience.

Primary topic: RNA regulation and disease (77%)

Related topic: RNA regulation and disease (77%)

Wikidata ID: wiki/Q17709596

OpenAlex ID: keywords/adar3

Dynamic landscape and regulation of RNA editing in mammals

2017 · Meng How Tan, Qin Li, et al. · Nature · 627

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A third member of the RNA-specific adenosine deaminase gene family, ADAR3, contains both single- and double-stranded RNA binding domains

2000 · CHUN-XIA CHEN, DAN-SUNG C. CHO, et al. · RNA · 524

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Adenosine deaminases acting on RNA (ADARs) are both antiviral and proviral

2011 · Charles E. Samuel · Virology · 315

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Requirement of Dimerization for RNA Editing Activity of Adenosine Deaminases Acting on RNA

2003 · Dan-Sung C. Cho, Weidong Yang, et al. · Journal of Biological Chemistry · 195

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Down-regulation of RNA Editing in Pediatric Astrocytomas

2008 · Caterina Cenci, Rita Barzotti, et al. · Journal of Biological Chemistry · 190

Profound downregulation of the RNA editing enzyme ADAR2 in ALS spinal motor neurons

2011 · Takuto Hideyama, Takenari Yamashita, et al. · Neurobiology of Disease · 189

Adenosine Deaminase That Acts on RNA 3 (ADAR3) Binding to Glutamate Receptor Subunit B Pre-mRNA Inhibits RNA Editing in Glioblastoma

2017 · Eimile Oakes, Ashley Anderson, et al. · Journal of Biological Chemistry · 181

A-to-I RNA Editing: Recent News and Residual Mysteries

2003 · Stefan Maas, Alexander Rich, et al. · Journal of Biological Chemistry · 181

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ADAR1 RNA Deaminase Limits Short Interfering RNA Efficacy in Mammalian Cells

2004 · Weidong Yang, Qingde Wang, et al. · Journal of Biological Chemistry · 140

Origins and evolution of ADAR‐mediated RNA editing

2009 · Yongfeng Jin, Wenjing Zhang, et al. · IUBMB Life · 114

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Adenosine Deaminases Acting on RNA (ADARs) and Viral Infections

2021 · Christian K. Pfaller, Cyril X. George, et al. · Annual Review of Virology · 89

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RNA Editing, ADAR1, and the Innate Immune Response

2017 · Qingde Wang, Xiaoni Li, et al. · Genes · 84

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Adar3 Is Involved in Learning and Memory in Mice

2018 · Dessislava Mladenova, Guy Barry, et al. · Frontiers in Neuroscience · 82

Evidence for a Susceptibility Locus on Chromosome 10p15 in Early-Onset Obsessive-Compulsive Disorder

2007 · Gregory L. Hanna, Jeremy Veenstra-VanderWeele, et al. · Biological Psychiatry · 77

RNA binding by ADAR3 inhibits adenosine-to-inosine editing and promotes expression of immune response protein MAVS

2022 · Reshma Raghava Kurup, Eimile K. Oakes, et al. · Journal of Biological Chemistry · 75

Low editing efficiency of GluR2 mRNA is associated with a low relative abundance of ADAR2 mRNA in white matter of normal human brain

2003 · Yukio Kawahara, Kyoko Ito, et al. · European Journal of Neuroscience · 73

Identification of a selective nuclear import signal in adenosine deaminases acting on RNA

2009 · Stefan Maas, Willemijn M. Gommans · Nucleic Acids Research · 61

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Glutamate drugs and pharmacogenetics of OCD: a pathway-based exploratory approach

2013 · Marco A Grados, Matt W Specht, et al. · Expert Opinion on Drug Discovery · 49

ADAR3 expression is an independent prognostic factor in lower-grade diffuse gliomas and positively correlated with the editing level of GRIA2Q607R

2018 · Ying Zhang, Kuanyu Wang, et al. · Cancer Cell International · 46

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Patterns of developmental expression of the RNA editing enzyme rADAR2

1999 · M.-C. Paupard, M.A. O'Connell, et al. · Neuroscience · 42

RNA binding candidates for human ADAR3 from substrates of a gain of function mutant expressed in neuronal cells

2019 · Yuru Wang, Dong hee Chung, et al. · Nucleic Acids Research · 41

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Nuclear aggregates of NONO/SFPQ and A-to-I-edited RNA in Parkinson’s disease and dementia with Lewy bodies

2024 · Nandkishore R. Belur, Bernabe I. Bustos, et al. · Neuron · 28

ADAR Family Proteins: A Structural Review

2024 · Carolyn N. Ashley, Emmanuel Broni, et al. · Current Issues in Molecular Biology · 26

Folate metabolism negatively regulates OAS-mediated antiviral innate immunity via ADAR3/endogenous dsRNA pathway

2023 · Jing Wu, Qiao You, et al. · Metabolism · 26

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The role of ADAR1 through and beyond its editing activity in cancer

2024 · Yue Jiao, Yuqin Xu, et al. · Cell Communication and Signaling · 25

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Works count: 87

Citation count: 3,600