Keyword

Ames test

Description: A microbiological assay used to assess whether a chemical can cause mutations, often as an indicator of potential genotoxicity.

Primary topic: Carcinogens and Genotoxicity Assessment (65%)

Wikidata ID: wiki/Q30912

OpenAlex ID: keywords/ames-test

Revised methods for the Salmonella mutagenicity test

1983 · Dorothy M. Maron, Bruce N. Ames · Mutation Research/Environmental Mutagenesis and Related Subjects · 7,446

The Ames Salmonella/microsome mutagenicity assay

2000 · Kristien Mortelmans, Errol Zeiger · Mutation research. Fundamental and molecular mechanisms of mutagenesis · 2,100

Salmonella mutagenicity test results for 250 chemicals

1983 · Steve Haworth, Timothy Lawlor, et al. · Environmental Mutagenesis · 898

Structure-activity relationship of mutagenic aromatic and heteroaromatic nitro compounds. Correlation with molecular orbital energies and hydrophobicity

1991 · Asim Kumar Debnath, Rosa L. Lopez de Compadre, et al. · Journal of Medicinal Chemistry · 870

Primary mutagenicity screening of food additives currently used in Japan

1984 · M. Ishidate, T. Sofuni, et al. · Food and Chemical Toxicology · 817

Prediction of Chemical Carcinogenicity in Rodents from in Vitro Genetic Toxicity Assays

1987 · Raymond W. Tennant, Barry H. Margolin, et al. · Science · 811

Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens

2005 · David Kirkland, Marilyn Aardema, et al. · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · 755

A new Salmonella tester strain (TA102) with A X T base pairs at the site of mutation detects oxidative mutagens.

1982 · D E Levin, M Hollstein, et al. · Proceedings of the National Academy of Sciences · 752

Toxic and genotoxic evaluation of six antibiotics on non-target organisms

2005 · Marina Isidori, Margherita Lavorgna, et al. · The Science of The Total Environment · 680

Derivation and Validation of Toxicophores for Mutagenicity Prediction

2004 · Jeroen Kazius, Ross McGuire, et al. · Journal of Medicinal Chemistry · 669

Screening of tabacco smoke constituents for mutagenicity using the Ames' test

1980 · Inger Florin, Lars Rutberg, et al. · Toxicology · 619

Mechanisms of genotoxicity. A review ofin vitroandin vivostudies with engineered nanoparticles

2013 · Zuzana Magdolenova, Andrew Collins, et al. · Nanotoxicology · 616

Mutagens in surface waters: a review

2004 · Takeshi Ohe, Tetsushi Watanabe, et al. · Mutation Research/Reviews in Mutation Research · 537

Antioxidant and antimutagenic activities of pomegranate peel extracts

2002 · P.S. Negi, G.K. Jayaprakasha, et al. · Food Chemistry · 530

Scientific opinion on genotoxicity testing strategies applicable to food and feed safety assessment

2011 · EFSA Scientific Committee · EFSA Journal · 480

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Mutagenicity and Carcinogenicity of Nitroarenes and Their Sources in the Environment

1986 · Hiroshi Tokiwa, Yoshinari Ohnishi, et al. · Critical Reviews in Toxicology · 474

An empirical approach to the statistical analysis of mutagenesis data from the Salmonella test

1982 · Leslie Bernstein, John Kaldor, et al. · Mutation Research/Environmental Mutagenesis and Related Subjects · 444

The BlueScreen HC assay to predict the genotoxic potential of fragrance materials

2022 · Yax Thakkar, Kaushal Joshi, et al. · Mutagenesis · 425

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3,3′,5,5′-Tetramethylbenzidine as an Ames Test Negative Chromogen for Horse-Radish Peroxidase in Enzyme-Immunoassay

1981 · E. S. Bos, A. A. van der Doelen, et al. · Journal of Immunoassay · 402

Revised Methods for the Salmonella Mutagenicity Test

1984 · Dorothy M. Maron, Bruce N. Ames · Elsevier eBooks · 400

Evaluation of the Tobacco Heating System 2.2. Part 2: Chemical composition, genotoxicity, cytotoxicity, and physical properties of the aerosol

2016 · Jean-Pierre Schaller, Daniela Keller, et al. · Regulatory Toxicology and Pharmacology · 374

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Genotoxicity investigations on nanomaterials: Methods, preparation and characterization of test material, potential artifacts and limitations—Many questions, some answers

2008 · Robert Landsiedel, Maike Diana Kapp, et al. · Mutation Research/Reviews in Mutation Research · 371

Origin and evolution of high throughput screening

2007 · D A Pereira, J A Williams · British Journal of Pharmacology · 364

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Chemically‐induced unscheduled DNA synthesis in primary rat hepatocyte cultures: A comparison with bacterial mutagenicity using 218 compounds

1981 · Gregory S. Probst, Robert E. McMahon, et al. · Environmental Mutagenesis · 360

Comparative use of bacterial, algal and protozoan tests to study toxicity of azo- and anthraquinone dyes

2005 · Čeněk Novotný, Nicolina Dias, et al. · Chemosphere · 352

Works count: 7,983

Citation count: 140,300