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Keyword

AMPKα2

Description: The alpha-2 catalytic subunit of AMP-activated protein kinase, an enzyme involved in cellular energy regulation and encoded by the PRKAA2 gene.
Wikidata ID: wiki/Q18030757
OpenAlex ID: keywords/ampkalpha2
Metformin Increases AMP-Activated Protein Kinase Activity in Skeletal Muscle of Subjects With Type 2 Diabetes
2002 · Nicolas Musi, Michael F. Hirshman, et al. · Diabetes · 805
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AMP-Activated Protein Kinase–Deficient Mice Are Resistant to the Metabolic Effects of Resveratrol
2009 · Jee-Hyun Um, Sung-Jun Park, et al. · Diabetes · 646
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Deficiency of LKB1 in skeletal muscle prevents AMPK activation and glucose uptake during contraction
2005 · Kei Sakamoto, Afshan McCarthy, et al. · The EMBO Journal · 544
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AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons
2007 · Marc Claret, Mark A. Smith, et al. · Journal of Clinical Investigation · 510
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Short-Term Overexpression of a Constitutively Active Form of AMP-Activated Protein Kinase in the Liver Leads to Mild Hypoglycemia and Fatty Liver
2005 · Marc Foretz, Nicolas Ancellin, et al. · Diabetes · 388
AMP-Activated Protein Kinase (AMPK) Is Activated in Muscle of Subjects With Type 2 Diabetes During Exercise
2001 · Nicolas Musi, Nobuharu Fujii, et al. · Diabetes · 371
Exercise Induces Isoform-Specific Increase in 5′AMP-Activated Protein Kinase Activity in Human Skeletal Muscle
2000 · Nobuharu Fujii, Tatsuya Hayashi, et al. · Biochemical and Biophysical Research Communications · 350
AMPKα2 Protects Against the Development of Heart Failure by Enhancing Mitophagy via PINK1 Phosphorylation
2017 · Bei Wang, Jiali Nie, et al. · Circulation Research · 331
Skeletal Muscle Adaptation to Exercise Training
2007 · Katja S.C. Röckl, Michael F. Hirshman, et al. · Diabetes · 305
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Activity of LKB1 and AMPK-related kinases in skeletal muscle: effects of contraction, phenformin, and AICAR
2004 · Kei Sakamoto, Olga Göransson, et al. · American Journal of Physiology-Endocrinology and Metabolism · 299
AMPKα2 Deletion Causes Aberrant Expression and Activation of NAD(P)H Oxidase and Consequent Endothelial Dysfunction In Vivo
2010 · Shuangxi Wang, Miao Zhang, et al. · Circulation Research · 296
Nicotinamide phosphoribosyltransferase protects against ischemic stroke through SIRT1‐dependent adenosine monophosphate–activated kinase pathway
2011 · Pei Wang, Tian‐Ying Xu, et al. · Annals of Neurology · 288
Metformin activates AMP-activated protein kinase in primary human hepatocytes by decreasing cellular energy status
2011 · X. Stephenne, M. Foretz, et al. · Diabetologia · 282
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Shear stress, SIRT1, and vascular homeostasis
2010 · Zhen Chen, I-Chen Peng, et al. · Proceedings of the National Academy of Sciences · 281
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The Role of AMPK in the Regulation of Skeletal Muscle Size, Hypertrophy, and Regeneration
2018 · David M. Thomson · International Journal of Molecular Sciences · 266
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Reduction of AMP-Activated Protein Kinase α2 Increases Endoplasmic Reticulum Stress and Atherosclerosis In Vivo
2010 · Yunzhou Dong, Miao Zhang, et al. · Circulation · 263
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AMP-Activated Protein Kinase Functionally Phosphorylates Endothelial Nitric Oxide Synthase Ser633
2009 · Zhen Chen, I-Chen Peng, et al. · Circulation Research · 263
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Matrine attenuates oxidative stress and cardiomyocyte apoptosis in doxorubicin-induced cardiotoxicity via maintaining AMPKα/UCP2 pathway
2019 · Can Hu, Xin Zhang, et al. · Acta Pharmaceutica Sinica B · 261
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AMPK activation counteracts cardiac hypertrophy by reducing O-GlcNAcylation
2018 · Roselle Gélinas, Florence Mailleux, et al. · Nature Communications · 253
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Activation of AMP-activated protein kinase α2 by nicotine instigates formation of abdominal aortic aneurysms in mice in vivo
2012 · Shuangxi Wang, Cheng Zhang, et al. · Nature Medicine · 250
Activation of 5′-AMP-activated Kinase with Diabetes Drug Metformin Induces Casein Kinase Iɛ (CKIɛ)-dependent Degradation of Clock Protein mPer2
2007 · Jee Hyun Um, Shutong Yang, et al. · Journal of Biological Chemistry · 244
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Chemical Genetic Screen for AMPKα2 Substrates Uncovers a Network of Proteins Involved in Mitosis
2011 · Max R. Banko, Jasmina J. Allen, et al. · Molecular Cell · 243
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Liver Adenosine Monophosphate-Activated Kinase-α2 Catalytic Subunit Is a Key Target for the Control of Hepatic Glucose Production by Adiponectin and Leptin But Not Insulin
2006 · Fabrizio Andreelli, Marc Foretz, et al. · Endocrinology · 237
AMPK controls exercise endurance, mitochondrial oxidative capacity, and skeletal muscle integrity
2014 · Louise Lantier, Joachim Fentz, et al. · The FASEB Journal · 227
Deficiency of LKB1 in heart prevents ischemia-mediated activation of AMPKα2 but not AMPKα1
2005 · Kei Sakamoto, Elham Zarrinpashneh, et al. · American Journal of Physiology-Endocrinology and Metabolism · 220
Works count: 800
Citation count: 26,560
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