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Keyword

APOBEC

Description: A family of cytidine deaminase enzymes that modify nucleic acids, including through RNA editing and DNA mutation.
Wikidata ID: wiki/Q4653351
OpenAlex ID: keywords/apobec
Restricting retrotransposons: a review
2016 · John L. Goodier · Mobile DNA · 434
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APOBEC-mediated viral restriction: not simply editing?
2007 · Rebecca K. Holmes, Michael H. Malim, et al. · Trends in Biochemical Sciences · 280
APOBEC-Mediated Editing of Viral RNA
2004 · Kate N. Bishop, Rebecca K. Holmes, et al. · Science · 248
APOBEC: A molecular driver in cervical cancer pathogenesis
2020 · Sundaramoorthy Revathidevi, Avaniyapuram Kannan Murugan, et al. · Cancer Letters · 196
Programmable C:G to G:C genome editing with CRISPR-Cas9-directed base excision repair proteins
2021 · Liwei Chen, Jung Eun Park, et al. · Nature Communications · 195
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Evolution of the deaminase fold and multiple origins of eukaryotic editing and mutagenic nucleic acid deaminases from bacterial toxin systems
2011 · Lakshminarayan M. Iyer, Dapeng Zhang, et al. · Nucleic Acids Research · 188
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High‐efficient and precise base editing of C•G to T•A in the allotetraploid cotton (Gossypium hirsutum) genome using a modified CRISPR /Cas9 system
2019 · Lei Qin, Jianying Li, et al. · Plant Biotechnology Journal · 178
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Increased Atherosclerosis in Mice Lacking Apolipoprotein A-I Attributable to Both Impaired Reverse Cholesterol Transport and Increased Inflammation
2005 · Ryan E. Moore, Mohamad Navab, et al. · Circulation Research · 173
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DNA Deamination in Immunity: AID in the Context of Its APOBEC Relatives
2007 · Silvestro G. Conticello, Marc‐Andre Langlois, et al. · Advances in immunology · 159
Cytosine Methylation and DNA Repair
2006 · C. P. Walsh, G. L. Xu · Springer eBooks · 139
DNA-uracil and human pathology
2007 · Mirta M.L. Sousa, Hans E. Krokan, et al. · Molecular Aspects of Medicine · 133
Distinct Subtypes of Gastric Cancer Defined by Molecular Characterization Include Novel Mutational Signatures with Prognostic Capability
2016 · Xiangchun Li, William K.K. Wu, et al. · Cancer Research · 120
AID/APOBEC cytosine deaminase induces genome-wide kataegis
2012 · Artem G Lada, Alok Dhar, et al. · Biology Direct · 103
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Potential APOBEC-mediated RNA editing of the genomes of SARS-CoV-2 and other coronaviruses and its impact on their longer term evolution
2021 · Jeremy Ratcliff, Peter Simmonds · Virology · 102
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Host-directed editing of the SARS-CoV-2 genome
2020 · Tobias Mourier, Mukhtar Sadykov, et al. · Biochemical and Biophysical Research Communications · 97
Increased RNA Editing May Provide a Source for Autoantigens in Systemic Lupus Erythematosus
2018 · Shalom Hillel Roth, Miri Danan-Gotthold, et al. · Cell Reports · 92
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Phage defence by deaminase-mediated depletion of deoxynucleotides in bacteria
2022 · Brian Y. Hsueh, Geoffrey B. Severin, et al. · Nature Microbiology · 90
DNA Editing by APOBECs: A Genomic Preserver and Transformer
2015 · Binyamin A. Knisbacher, Doron Gerber, et al. · Trends in Genetics · 78
Point mutation bias in SARS-CoV-2 variants results in increased ability to stimulate inflammatory responses
2020 · Masato Kosuge, Emi Furusawa-Nishii, et al. · Scientific Reports · 77
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Restricting HIV the SAMHD1 way: through nucleotide starvation
2012 · Diana Ayinde, Nicoletta Casartelli, et al. · Nature Reviews Microbiology · 73
APOBEC: From mutator to editor
2017 · Bei Yang, Xiaosa Li, et al. · Journal of genetics and genomics/Journal of Genetics and Genomics · 69
RNA as the substrate for epigenome‐environment interactions
2010 · John S. Mattick · BioEssays · 68
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Substrate and cofactor requirements for RNA editing of chloroplast transcripts in Arabidopsis in vitro
2005 · Carla E. Hegeman, Michael L. Hayes, et al. · The Plant Journal · 63
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Host Factors and HIV-1 Replication: Clinical Evidence and Potential Therapeutic Approaches
2013 · Mariana Santa-Marta, Paula Matos de Brito, et al. · Frontiers in Immunology · 62
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Proteolytic degradation of the nuclear isoform of uracil-DNA glycosylase occurs during the S phase of the cell cycle
2004 · Jennifer A. Fischer, Susan Muller-Weeks, et al. · DNA repair · 62
Works count: 245
Citation count: 5,193
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