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Keyword

apolipoprotein E

Description: Apolipoprotein E is a mammalian protein involved in lipid transport and metabolism, with roles studied in neurology and other biomedical fields.
Wikidata ID: wiki/Q424728
OpenAlex ID: keywords/apolipoprotein-e
Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset Families
1993 · E. H. Corder, A. M. Saunders, et al. · Science · 9,425
Alzheimer's disease
2021 · Philip Scheltens, Bart De Strooper, et al. · The Lancet · 5,393
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Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium
1997 · L. A. Farrer · JAMA · 4,664
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease
2013 · European Alzheimer's Disease Initiative (EADI), Jean-Charles Lambert, et al. · Nature Genetics · 4,325
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Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease.
1993 · W J Strittmatter, A M Saunders, et al. · Proceedings of the National Academy of Sciences · 4,269
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Apolipoprotein E: Cholesterol Transport Protein with Expanding Role in Cell Biology
1988 · Robert W. Mahley · Science · 4,028
Association of apolipoprotein E allele ϵ4 with late‐onset familial and sporadic Alzheimer's disease
1993 · A. M. Saunders, W. J. Strittmatter, et al. · Neurology · 3,783
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Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy
2013 · Chia-Chen Liu, Takahisa Kanekiyo, et al. · Nature Reviews Neurology · 3,442
Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease
2009 · Denise Harold, Richard Abraham, et al. · Nature Genetics · 3,325
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Plasma Homocysteine as a Risk Factor for Dementia and Alzheimer's Disease
2002 · Sudha Seshadri, Alexa Beiser, et al. · New England Journal of Medicine · 3,234
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The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases
2017 · Susanne Krasemann, Charlotte Madore, et al. · Immunity · 2,939
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Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI.
1990 · JE Hixson, DT Vernier · Journal of Lipid Research · 2,933
Spontaneous Hypercholesterolemia and Arterial Lesions in Mice Lacking Apolipoprotein E
1992 · Sunny H. Zhang, Robert L. Reddick, et al. · Science · 2,235
Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease
2009 · the European Alzheimer's Disease Initiative Investigators, Jean-Charles Lambert, et al. · Nature Genetics · 2,231
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Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease
1994 · E. H. Corder, A. M. Saunders, et al. · Nature Genetics · 1,916
Apolipoprotein E: Far More Than a Lipid Transport Protein
2000 · Robert W. Mahley, Stanley C. Rall · Annual Review of Genomics and Human Genetics · 1,836
CNS Synaptogenesis Promoted by Glia-Derived Cholesterol
2001 · Daniela H. Mauch, Karl Nägler, et al. · Science · 1,706
Effect of oestrogen during menopause on risk and age at onset of Alzheimer's disease
1996 · Ming-Xin Tang, Diane Jacobs, et al. · The Lancet · 1,647
The Role of Apolipoprotein E in Alzheimer's Disease
2009 · Jungsu Kim, Jacob M. Basak, et al. · Neuron · 1,618
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Newly identified loci that influence lipid concentrations and risk of coronary artery disease
2008 · Cristen J Willer, Serena Sanna, et al. · Nature Genetics · 1,585
Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report
2019 · Peter T Nelson, Dennis W Dickson, et al. · Brain · 1,542
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Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease.
1993 · D E Schmechel, A M Saunders, et al. · Proceedings of the National Academy of Sciences · 1,524
Thematic review series: The Pathogenesis of Atherosclerosis. Effects of infection and inflammation on lipid and lipoprotein metabolism mechanisms and consequences to the host
2004 · Weerapan Khovidhunkit, Min-Sun Kim, et al. · Journal of Lipid Research · 1,481
Apolipoprotein E and Alzheimer disease: pathobiology and targeting strategies
2019 · Yu Yamazaki, Na Zhao, et al. · Nature Reviews Neurology · 1,415
Clearance of Alzheimer’s amyloid-β1-40 peptide from brain by LDL receptor–related protein-1 at the blood-brain barrier
2000 · Masayoshi Shibata, Shinya Yamada, et al. · Journal of Clinical Investigation · 1,412
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Works count: 27,610
Citation count: 918,400
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