Keyword

ATG5

Description: ATG5 is a human gene encoding a protein involved in autophagy, a cellular process that degrades and recycles intracellular components.

Primary topic: Autophagy in Disease and Therapy (43%)

Wikidata ID: wiki/Q18034312

OpenAlex ID: keywords/atg5

Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

2006 · Taichi Hara, Kenji Nakamura, et al. · Nature · 3,873

Autophagy promotes ferroptosis by degradation of ferritin

2016 · Wen Hou, Yangchun Xie, et al. · Autophagy · 2,319

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Autophagosomes form at ER–mitochondria contact sites

2013 · Maho Hamasaki, Nobumichi Furuta, et al. · Nature · 1,744

Inhibition of Macroautophagy Triggers Apoptosis

2005 · Patricia Boya, Rosa-Ana González-Polo, et al. · Molecular and Cellular Biology · 1,628

Mitochondrial Autophagy Is an HIF-1-dependent Adaptive Metabolic Response to Hypoxia

2008 · Huafeng Zhang, Marta Bosch-Marce, et al. · Journal of Biological Chemistry · 1,601

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A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells

2008 · Ken Cadwell, John Y. Liu, et al. · Nature · 1,538

The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress

2007 · Atsuko Nakai, Osamu Yamaguchi, et al. · Nature Medicine · 1,519

A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy

2008 · In Hye Lee, Liu Cao, et al. · Proceedings of the National Academy of Sciences · 1,477

Mitochondria Supply Membranes for Autophagosome Biogenesis during Starvation

2010 · Dale W. Hailey, Angelika S. Rambold, et al. · Cell · 1,429

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Toll-like receptor signalling in macrophages links the autophagy pathway to phagocytosis

2007 · Miguel A. Sanjuan, Christopher P. Dillon, et al. · Nature · 1,345

Autophagy-deficient mice develop multiple liver tumors

2011 · Akito Takamura, Masaaki Komatsu, et al. · Genes & Development · 1,341

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Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis

2006 · Shida Yousefi, Remo Perozzo, et al. · Nature Cell Biology · 1,297

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Defective Hepatic Autophagy in Obesity Promotes ER Stress and Causes Insulin Resistance

2010 · Ling Yang, Ping Li, et al. · Cell Metabolism · 1,271

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Autophagy induction via STING trafficking is a primordial function of the cGAS pathway

2019 · Xiang Gui, Hui Yang, et al. · Nature · 1,260

Cardioprotection and lifespan extension by the natural polyamine spermidine

2016 · Tobias Eisenberg, Mahmoud Abdellatif, et al. · Nature Medicine · 1,166

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Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma

2007 · Ravi K. Amaravadi, Duonan Yu, et al. · Journal of Clinical Investigation · 1,137

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Discovery of Atg5/Atg7-independent alternative macroautophagy

2009 · Yuya Nishida, Satoko Arakawa, et al. · Nature · 1,102

Autophagy Defends Cells Against Invading Group A Streptococcus

2004 · Ichiro Nakagawa, Atsuo Amano, et al. · Science · 1,090

NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation

2009 · Rachel Cooney, John Baker, et al. · Nature Medicine · 1,047

Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1–phosphatidylinositol-3-kinase complex

2009 · Yun Zhong, Qing Jun Wang, et al. · Nature Cell Biology · 1,004

Interactions between Autophagy Receptors and Ubiquitin-like Proteins Form the Molecular Basis for Selective Autophagy

2014 · Vladimir Rogov, Volker Dötsch, et al. · Molecular Cell · 992

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Autophagy‐based unconventional secretory pathway for extracellular delivery of IL‐1β

2011 · Nicolas Dupont, Shanya Jiang, et al. · The EMBO Journal · 965

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Role and Regulation of Starvation-Induced Autophagy in the Drosophila Fat Body

2004 · Ryan C. Scott, Oren Schuldiner, et al. · Developmental Cell · 963

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Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis

2007 · Yoshinori Takahashi, Domenico Coppola, et al. · Nature Cell Biology · 927

Escape of Intracellular Shigella from Autophagy

2004 · Michinaga Ogawa, Tamotsu Yoshimori, et al. · Science · 828

Works count: 5,935

Citation count: 238,000