Keyword

axotomy

Description: The experimental or pathological severing of a neuron's axon, studied for its effects on neural function, regeneration, and cell survival.

Primary topic: Nerve injury and regeneration (57%)

Wikidata ID: wiki/Q792615

OpenAlex ID: keywords/axotomy

Neurotoxic reactive astrocytes are induced by activated microglia

2017 · Shane A. Liddelow, Kevin A. Guttenplan, et al. · Nature · 7,931

Functions of the neurotrophins during nervous system development: What the knockouts are teaching us

1994 · William D. Snider · Cell · 1,428

Inducible and constitutive transcription factors in the mammalian nervous system: control of gene expression by Jun, Fos and Krox, and CREB/ATF proteins

1998 · T. Herdegen, J.D. Leah · Brain Research Reviews · 1,351

GDNF: a Potent Survival Factor for Motoneurons Present in Peripheral Nerve and Muscle

1994 · Christopher E. Henderson, Heidi S. Phillips, et al. · Science · 1,273

The cellular and molecular basis of peripheral nerve regeneration

1997 · Susan Y. Fu, Tessa Gordon · Molecular Neurobiology · 1,202

Neuronal Cell Death

2018 · Michael Fricker, Aviva M. Tolkovsky, et al. · Physiological Reviews · 1,127

The Axon Reaction: A Review of the Principal Features of Perikaryal Responses to Axon Injury

1971 · A.R. Lieberman · International review of neurobiology · 1,115

Peripheral nerve injury triggers central sprouting of myelinated afferents

1992 · Clifford J. Woolf, Peter Shortland, et al. · Nature · 1,078

Retinal ganglion cell death in experimental glaucoma and after axotomy occurs by apoptosis.

1995 · H A Quigley, R W Nickells, et al. · PubMed · 932

Nerve Growth Factor Treatment After Brain Injury Prevents Neuronal Death

1987 · Lawrence F. Kromer · Science · 932

Autoimmune T cells protect neurons from secondary degeneration after central nervous system axotomy

1999 · Gila Moalem, Raya Leibowitz–Amit, et al. · Nature Medicine · 889

Neural plasticity after peripheral nerve injury and regeneration

2007 · X. Navarro, Meritxell Vivó, et al. · Progress in Neurobiology · 883

Ciliary neurotrophic factor prevents the degeneration of motor neurons after axotomy

1990 · Michael Sendtner, Georg W. Kreutzberg, et al. · Nature · 833

Axotomy results in delayed death and apoptosis of retinal ganglion cells in adult rats

1994 · M Berkelaar, DB Clarke, et al. · Journal of Neuroscience · 815

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Activating Transcription Factor 3 (ATF3) Induction by Axotomy in Sensory and Motoneurons: A Novel Neuronal Marker of Nerve Injury

2000 · Hiroaki Tsujino, Eiji Kondo, et al. · Molecular and Cellular Neuroscience · 766

BAX Is Required for Neuronal Death after Trophic Factor Deprivation and during Development

1996 · Thomas L Deckwerth, Jeffrey L Elliott, et al. · Neuron · 749

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Messenger plasticity in primary sensory neurons following axotomy and its functional implications

1994 · T. Hökfelt, X. Zhang, et al. · Trends in Neurosciences · 740

Peripheral nerve injury triggers noradrenergic sprouting within dorsal root ganglia

1993 · Elspeth M. McLachlan, Wilfrid Jänig, et al. · Nature · 740

Experimental autoimmune encephalomyelitis repressed by microglial paralysis

2005 · Frank L Heppner, Melanie Greter, et al. · Nature Medicine · 731

Neurofilament gene expression: a major determinant of axonal caliber.

1987 · P N Hoffman, D W Cleveland, et al. · Proceedings of the National Academy of Sciences · 720

Brain-derived neurotrophic factor prevents the death of motoneurons in newborn rats after nerve section

1992 · M. Sendtner, B. Holtmann, et al. · Nature · 707

Neurodegeneration in Excitotoxicity, Global Cerebral Ischemia, and Target Deprivation: A Perspective on the Contributions of Apoptosis and Necrosis

1998 · Lee J. Martin, Nael A. Al-Abdulla, et al. · Brain Research Bulletin · 703

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Peripheral nerve regeneration and neurotrophic factors

1999 · GIORGIO TERENGHI · Journal of Anatomy · 696

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Differential expression of mRNAs for neurotrophins and their receptors after axotomy of the sciatic nerve.

1993 · H Funakoshi, J Frisén, et al. · The Journal of Cell Biology · 688

dSarm/Sarm1 Is Required for Activation of an Injury-Induced Axon Death Pathway

2012 · Jeannette M. Osterloh, Jing Yang, et al. · Science · 687

Works count: 5,882

Citation count: 266,200