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BD1047
Description:
BD1047 is a chemical compound used in neuroscience research as an antagonist of the sigma-1 receptor.
Primary topic:
Pharmacological Receptor Mechanisms and Effects (65%)
Related topics:
Pharmacological Receptor Mechanisms and Effects (65%),
Pain Mechanisms and Treatments (12%)
Wikidata ID:
wiki/Q4835353
OpenAlex ID:
keywords/bd1047
The anti‐amnesic and neuroprotective effects of donepezil against amyloid β25‐35peptide‐induced toxicity in mice involve an interaction with theσ1receptor
2006
·
J Meunier
, J Ieni
, et al.
·
British Journal of Pharmacology
·
288
PDF
Characterization of two novel σ receptor ligands: antidystonic effects in rats suggest σ receptor antagonism
1995
·
Rae R. Matsumoto
, Wayne D. Bowen
, et al.
·
European Journal of Pharmacology
·
268
The antidepressant-like effect induced by sigma(1)-receptor agonists and neuroactive steroids in mice submitted to the forced swimming test.
2001
·
A Urani
, F J Roman
, et al.
·
PubMed
·
181
Involvement of sigma (σ) receptors in the acute actions of methamphetamine: Receptor binding and behavioral studies
2005
·
Emily C. Nguyen
, Kari A. McCracken
, et al.
·
Neuropharmacology
·
146
Sigma-1 Receptor Regulation of Voltage-Gated Calcium Channels Involves a Direct Interaction
2008
·
Kissaou T. Tchedre
, Ren-Qi Huang
, et al.
·
Investigative Ophthalmology & Visual Science
·
139
Anti-amnesic and neuroprotective potentials of the mixed muscarinic receptor/sigma 1 (σ 1 ) ligand ANAVEX2-73, a novel aminotetrahydrofuran derivative
2010
·
Vanessa Villard
, Julie Espallergues
, et al.
·
Journal of Psychopharmacology
·
138
Intrathecal Injection of the ς1Receptor Antagonist BD1047 Blocks Both Mechanical Allodynia and Increases in Spinal NR1 Expression during the Induction Phase of Rodent Neuropathic Pain
2008
·
Dae-Hyun Roh
, Hyun-Woo Kim
, et al.
·
Anesthesiology
·
127
PDF
Chronic Antidepressants Potentiate via Sigma-1 Receptors the Brain-derived Neurotrophic Factor-induced Signaling for Glutamate Release
2006
·
Yuki Yagasaki
, Tadahiro Numakawa
, et al.
·
Journal of Biological Chemistry
·
122
PDF
Involvement of the Sigma1 Receptor in Cocaine-induced Conditioned Place Preference Possible Dependence on Dopamine Uptake Blockade
2002
·
P Romieu
·
Neuropsychopharmacology
·
119
Two novel σ receptor ligands, BD1047 and LR172, attenuate cocaine-induced toxicity and locomotor activity
1999
·
Kari A. McCracken
, Wayne D. Bowen
, et al.
·
European Journal of Pharmacology
·
111
Involvement of the σ1 receptor in the cocaine-induced conditioned place preference
2000
·
Pascal Romieu
, Rémi Martin-Fardon
, et al.
·
Neuroreport
·
107
Antiamnesic and Neuroprotective Effects of the Aminotetrahydrofuran Derivative ANAVEX1-41 Against Amyloid β25–35-Induced Toxicity in Mice
2008
·
Vanessa Villard
, Julie Espallergues
, et al.
·
Neuropsychopharmacology
·
105
Involvement of Sigma-1 Receptors in the Antidepressant-like Effects of Dextromethorphan
2014
·
Linda Nguyen
, Matthew J. Robson
, et al.
·
PLoS ONE
·
99
PDF
σ-1 Receptors Protect RGC-5 Cells from Apoptosis by Regulating Intracellular Calcium, Bax Levels, and Caspase-3 Activation
2008
·
Kissaou T. Tchedre
, Thomas Yorio
·
Investigative Ophthalmology & Visual Science
·
94
Evaluation of sigma (σ) receptors in the antidepressant-like effects of ketamine in vitro and in vivo
2011
·
Matthew J. Robson
, Meenal Elliott
, et al.
·
European Neuropsychopharmacology
·
93
New Positron Emission Tomography (PET) Radioligand for Imaging σ-1 Receptors in Living Subjects
2012
·
Michelle L. James
, Bin Shen
, et al.
·
Journal of Medicinal Chemistry
·
92
Rubiscolin-6, a δ opioid peptide derived from spinach Rubisco, has anxiolytic effect via activating σ1 and dopamine D1 receptors
2007
·
Hajime Hirata
, Soushi Sonoda
, et al.
·
Peptides
·
89
Interaction with σ1 Protein, but Not N-Methyl-d-aspartate Receptor, Is Involved in the Pharmacological Activity of Donepezil
2006
·
Tangui Maurice
, Johann Meunier
, et al.
·
Journal of Pharmacology and Experimental Therapeutics
·
80
The sigma1 (?1) receptor activation is a key step for the reactivation of cocaine conditioned place preference by drug priming
2004
·
Pascal Romieu
, Johann Meunier
, et al.
·
Psychopharmacology
·
79
Cocaine and σ-1 receptors modulate HIV infection, chemokine receptors, and the HPA axis in the huPBL-SCID model
2005
·
Michael D Roth
, Katherine M Whittaker
, et al.
·
Journal of Leukocyte Biology
·
78
Involvement of sigma-1 receptor in astrocyte activation induced by methamphetamine via up-regulation of its own expression
2015
·
Yuan Zhang
, Xuan Lv
, et al.
·
Journal of Neuroinflammation
·
76
PDF
Sigma 1 receptor activation regulates brain-derived neurotrophic factor through NR2A-CaMKIV-TORC1 pathway to rescue the impairment of learning and memory induced by brain ischaemia/reperfusion
2014
·
Qian Xu
, Xue-Fei Ji
, et al.
·
Psychopharmacology
·
75
Differential Effects of σ1 Receptor Blockade on Self-Administration and Conditioned Reinstatement Motivated by Cocaine vs Natural Reward
2007
·
Rémi Martin-Fardon
, Tangui Maurice
, et al.
·
Neuropsychopharmacology
·
70
Sigma-1 receptor stimulation attenuates calcium influx through activated L-type Voltage Gated Calcium Channels in purified retinal ganglion cells
2012
·
Brett H. Mueller
, Yong Park
, et al.
·
Experimental Eye Research
·
62
PDF
SA4503, a sigma-1 receptor agonist, prevents cultured cortical neurons from oxidative stress-induced cell death via suppression of MAPK pathway activation and glutamate receptor expression
2009
·
Tuerhong Tuerxun
, Tadahiro Numakawa
, et al.
·
Neuroscience Letters
·
62
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Works count:
155
Citation count:
4,852
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