Get started
Keyword

β-lapachone

Description: β-Lapachone is a naturally occurring naphthoquinone compound studied for its chemical properties and potential biological and medicinal effects.
OpenAlex ID: keywords/beta-lapachone
NAD(P)H:Quinone Oxidoreductase Activity Is the Principal Determinant of β-Lapachone Cytotoxicity
2000 · John J. Pink, Sarah M. Planchon, et al. · Journal of Biological Chemistry · 376
PDF
An NQO1- and PARP-1-mediated cell death pathway induced in non-small-cell lung cancer cells by β-lapachone
2007 · Erik A. Bey, Melissa S. Bentle, et al. · Proceedings of the National Academy of Sciences · 354
A Tumor‐Specific Cascade Amplification Drug Release Nanoparticle for Overcoming Multidrug Resistance in Cancers
2017 · Mingzhou Ye, Yuxin Han, et al. · Advanced Materials · 338
Superparamagnetic Iron Oxide Nanoparticles: Amplifying ROS Stress to Improve Anticancer Drug Efficacy
2013 · Gang Huang, Huabing Chen, et al. · Theranostics · 318
PDF
Antimalarial activity of phenazines from lapachol, β-lapachone and its derivatives against Plasmodium falciparum in vitro and Plasmodium berghei in vivo
2004 · Valter F de Andrade-Neto, Marı́lia O.F Goulart, et al. · Bioorganic & Medicinal Chemistry Letters · 314
Tumor‐Specific Drug Release and Reactive Oxygen Species Generation for Cancer Chemo/Chemodynamic Combination Therapy
2019 · Sheng Wang, Zhantong Wang, et al. · Advanced Science · 292
PDF
NAD(P)H:quinone oxidoreductase 1 (NQO1) in the sensitivity and resistance to antitumor quinones
2011 · David Siegel, Chao Yan, et al. · Biochemical Pharmacology · 272
Enhanced Antitumor Efficacy by a Cascade of Reactive Oxygen Species Generation and Drug Release
2019 · Sheng Wang, Guocan Yu, et al. · Angewandte Chemie International Edition · 271
Topoisomerase I Poisons and Suppressors as Anticancer Drugs
2000 · Christian Bailly · Current Medicinal Chemistry · 265
Selective killing of cancer cells by β-lapachone: Direct checkpoint activation as a strategy against cancer
2003 · Youzhi Li, Xiangao Sun, et al. · Proceedings of the National Academy of Sciences · 231
Three inhibitors of type 1 human immunodeficiency virus long terminal repeat-directed gene expression and virus replication.
1993 · C J Li, L J Zhang, et al. · Proceedings of the National Academy of Sciences · 230
A protein-based cGAS-STING nanoagonist enhances T cell-mediated anti-tumor immune responses
2022 · Xuan Wang, Yingqi Liu, et al. · Nature Communications · 222
PDF
The Trypanocidal Activity of Naphthoquinones: A Review
2009 · Antônio Ventura Pinto, Solange Lisboa de Castro · Molecules · 219
PDF
beta-Lapachone, a novel DNA topoisomerase I inhibitor with a mode of action different from camptothecin.
1993 · C.J. Li, L Averboukh, et al. · Journal of Biological Chemistry · 219
Cancer Therapy with ß-Lapachone
2002 · Arthur Pardee, You Li, et al. · Current Cancer Drug Targets · 215
Integrated block copolymer prodrug nanoparticles for combination of tumor oxidative stress amplification and ROS-responsive drug release
2018 · Wei Yin, Wendong Ke, et al. · Biomaterials · 202
Cyclodextrin-covered gold nanoparticles for targeted delivery of an anti-cancer drug
2009 · Chiyoung Park, Hyewon Youn, et al. · Journal of Materials Chemistry · 200
Cyr61 Expression Confers Resistance to Apoptosis in Breast Cancer MCF-7 Cells by a Mechanism of NF-κB-dependent XIAP Up-Regulation
2004 · Ming-Tsan Lin, Cheng-Chi Chang, et al. · Journal of Biological Chemistry · 193
PDF
Target to apoptosis: A hopeful weapon for prostate cancer
1997 · Dean G. Tang, Arthur T. Porter · The Prostate · 190
Red Lapacho (Tabebuia impetiginosa)—A global ethnopharmacological commodity?
2008 · J. Rubén Gómez Castellanos, José M. Prieto, et al. · Journal of Ethnopharmacology · 182
Anti-inflammatory effects of β-lapachone in lipopolysaccharide-stimulated BV2 microglia
2007 · Dong-Oh Moon, Yung Hyun Choi, et al. · International Immunopharmacology · 179
Predicting chemoresistance in human malignant glioma cells: The role of molecular genetic analyses
1998 · Michael Weller, Johannes Rieger, et al. · International Journal of Cancer · 179
PDF
NIR‐Actuated Remote Activation of Ferroptosis in Target Tumor Cells through a Photothermally Responsive Iron‐Chelated Biopolymer Nanoplatform
2021 · Chencheng Xue, Menghuan Li, et al. · Angewandte Chemie International Edition · 173
Efficacy of beta-lapachone in pancreatic cancer treatment: Exploiting the novel, therapeutic target NQO1
2005 · Matthew Ough, Anne Lewis, et al. · Cancer Biology & Therapy · 173
PDF
Implications of NQO1 in cancer therapy
2015 · Eun-Taex Oh, Heon Joo Park · BMB Reports · 170
PDF
Works count: 1,161
Citation count: 27,840
Year
Topic
Type