Keyword

botulinum neurotoxin A

Description: Botulinum neurotoxin A is a bacterial protein toxin that blocks neurotransmitter release by cleaving neuronal SNARE proteins.

Primary topic: Botulinum Toxin and Related Neurological Disorders (70%)

OpenAlex ID: keywords/botulinum-neurotoxin-a

Botulinum neurotoxin A selectively cleaves the synaptic protein SNAP-25

1993 · Juan Blasi, Edwin R. Chapman, et al. · Nature · 1,221

SV2 Is the Protein Receptor for Botulinum Neurotoxin A

2006 · Min Dong, Felix Yeh, et al. · Science · 770

Long-Distance Retrograde Effects of Botulinum Neurotoxin A

2008 · Flavia Antonucci, Chiara Rossi, et al. · Journal of Neuroscience · 450

PDF

Botulinum neurotoxins serotypes A and E cleave SNAP‐25 at distinct COOH‐terminal peptide bonds

1993 · Giampietro Schiavo, Annalisa Santucci, et al. · FEBS Letters · 438

Blocking Neuronal Signaling to Immune Cells Treats Streptococcal Invasive Infection

2018 · Felipe A. Pinho-Ribeiro, Buket Baddal, et al. · Cell · 436

PDF

Proteolysis of SNAP-25 by types E and A botulinal neurotoxins.

1994 · T. Binz, J. Blasi, et al. · Journal of Biological Chemistry · 434

Regulated Exocytosis Contributes to Protein Kinase C Potentiation of Vanilloid Receptor Activity

2004 · Cruz Morenilla-Palao, Rosa Planells-Cases, et al. · Journal of Biological Chemistry · 425

PDF

Protein kinase C modulates NMDA receptor trafficking and gating

2001 · Jian-yu Lan, Vytenis A. Skeberdis, et al. · Nature Neuroscience · 421

Reconstitution of Ca 2+ -Regulated Membrane Fusion by Synaptotagmin and SNAREs

2004 · Ward C. Tucker, Thomas Weber, et al. · Science · 374

Substrate recognition strategy for botulinum neurotoxin serotype A

2004 · Mark A. Breidenbach, Axel T. Brunger · Nature · 330

The synaptic vesicle protein 2C mediates the uptake of botulinum neurotoxin A into phrenic nerves

2006 · Stefan Mahrhold, Andreas Rummel, et al. · FEBS Letters · 315

Sequence homology and structural analysis of the clostridial neurotoxins

1999 · D.Borden Lacy, Raymond C Stevens · Journal of Molecular Biology · 311

Insulin promotes rapid delivery of N -methyl- d - aspartate receptors to the cell surface by exocytosis

2001 · Vytenis A. Skeberdis, Jian-yu Lan, et al. · Proceedings of the National Academy of Sciences · 306

PDF

SNAP-25, a t-SNARE which binds to both syntaxin and synaptobrevin via domains that may form coiled coils.

1994 · E R Chapman, S An, et al. · Journal of Biological Chemistry · 295

SNAP-25 is expressed in islets of Langerhans and is involved in insulin release.

1995 · K Sadoul, J Lang, et al. · The Journal of Cell Biology · 247

The C Terminus of SNAP25 Is Essential for Ca2+-dependent Binding of Synaptotagmin to SNARE Complexes

2000 · Roy R.L. Gerona, Eric C. Larsen, et al. · Journal of Biological Chemistry · 243

PDF

Activation of Store-Operated Ca2+ Current in Xenopus Oocytes Requires SNAP-25 but Not a Diffusible Messenger

1999 · Yong Yao, Antonio V Ferrer-Montiel, et al. · Cell · 242

PDF

Capsaicin-stimulated release of substance P from cultured dorsal root ganglion neurons: involvement of two distinct mechanisms

2000 · John Purkiss, Mary Welch, et al. · Biochemical Pharmacology · 239

ModelingPichia pastoris growth on methanol and optimizing the production of a recombinant protein, the heavy-chain fragment C of botulinum neurotoxin, serotype A

2000 · Wenhui Zhang, Mark A. Bevins, et al. · Biotechnology and Bioengineering · 234

Glycosylated SV2A and SV2B Mediate the Entry of Botulinum Neurotoxin E into Neurons

2008 · Min Dong, Huisheng Liu, et al. · Molecular Biology of the Cell · 230

Botulinum neurotoxins: from paralysis to recovery of functional neuromuscular transmission

2002 · Frédéric A Meunier, Giampietro Schiavo, et al. · Journal of Physiology-Paris · 226

The HCC‐domain of botulinum neurotoxins A and B exhibits a singular ganglioside binding site displaying serotype specific carbohydrate interaction

2003 · Andreas Rummel, Stefan Mahrhold, et al. · Molecular Microbiology · 217

PDF

Botulinum Neurotoxins A and E Undergo Retrograde Axonal Transport in Primary Motor Neurons

2012 · Laura Restani, Francesco Giribaldi, et al. · PLoS Pathogens · 194

PDF

Clostridial Neurotoxins and Substrate Proteolysis in Intact Neurons

1996 · Lura C. Williamson, Jane L. Halpern, et al. · Journal of Biological Chemistry · 193

PDF

Persistence of botulinum neurotoxin action in cultured spinal cord cells 1,2

1999 · James E Keller, Elaine A Neale, et al. · FEBS Letters · 172

Works count: 1,212

Citation count: 28,670