Keyword

BRD1

Description: A human protein-coding gene whose product is a bromodomain-containing protein involved in chromatin regulation and gene expression.

Primary topic: Protein Degradation and Inhibitors (73%)

Wikidata ID: wiki/Q18037642

OpenAlex ID: keywords/brd1

Incidence and diversity of PAX5 fusion genes in childhood acute lymphoblastic leukemia

2008 · K Nebral, D Denk, et al. · Leukemia · 204

The Hbo1-Brd1/Brpf2 complex is responsible for global acetylation of H3K14 and required for fetal liver erythropoiesis

2011 · Yuta Mishima, Satoru Miyagi, et al. · Blood · 198

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Enhanced Efficacy of Simultaneous PD-1 and PD-L1 Immune Checkpoint Blockade in High-Grade Serous Ovarian Cancer

2020 · Changxin Wan, Matthew P. Keany, et al. · Cancer Research · 194

Gene-Network Analysis Identifies Susceptibility Genes Related to Glycobiology in Autism

2009 · Bert van der Zwaag, Lude Franke, et al. · PLoS ONE · 145

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RAV-Like1Maintains Brassinosteroid Homeostasis via the Coordinated Activation ofBRI1and Biosynthetic Genes in Rice

2010 · Byoung Il Je, Hai Long Piao, et al. · The Plant Cell · 126

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JQ1 suppresses tumor growth through downregulating LDHA in ovarian cancer*

2015 · Haifeng Qiu, Amanda L. Jackson, et al. · Oncotarget · 96

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Evidence implicating BRD1 with brain development and susceptibility to both schizophrenia and bipolar affective disorder

2006 · J E Severinsen, C R Bjarkam, et al. · Molecular Psychiatry · 80

Bivalent complexes of PRC1 with orthologs of BRD4 and MOZ/MORF target developmental genes in Drosophila

2017 · Hyuckjoon Kang, Youngsook L. Jung, et al. · Genes & Development · 67

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Bromodomain-containing proteins BRD1, BRD2, and BRD13 are core subunits of SWI/SNF complexes and vital for their genomic targeting in Arabidopsis

2021 · Yaoguang Yu, Wei Fu, et al. · Molecular Plant · 60

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Synthesis and Demonstration of the Biological Relevance of sp3‐rich Scaffolds Distantly Related to Natural Product Frameworks

2017 · Daniel J. Foley, Philip G. E. Craven, et al. · Chemistry - A European Journal · 60

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Expression of BrD1, a Plant Defensin from Brassica rapa, Confers Resistance against Brown Planthopper (Nilaparvata lugens) in Transgenic Rices

2009 · Man-Soo Choi, Yul-Ho Kim, et al. · Molecules and Cells · 55

Support of association between BRD1 and both schizophrenia and bipolar affective disorder

2009 · Mette Nyegaard, Jacob E. Severinsen, et al. · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · 54

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Histone acetylation mediated by Brd1 is crucial for Cd8 gene activation during early thymocyte development

2014 · Yuta Mishima, Changshan Wang, et al. · Nature Communications · 41

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Bromodomain-containing subunits BRD1, BRD2, and BRD13 are required for proper functioning of SWI/SNF complexes in Arabidopsis

2021 · Kamila Jarończyk, Katarzyna Sosnowska, et al. · Plant Communications · 38

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Biallelic germline and somatic mutations in malignant mesothelioma: Multiple mutations in transcription regulators including mSWI/SNF genes

2014 · Yoshie Yoshikawa, Ayuko Sato, et al. · International Journal of Cancer · 37

DNA methylation epi-signature is associated with two molecularly and phenotypically distinct clinical subtypes of Phelan-McDermid syndrome

2021 · L. C. Schenkel, E. Aref-Eshghi, et al. · Clinical Epigenetics · 35

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Identification of the BRD1 interaction network and its impact on mental disorder risk

2016 · Tue Fryland, Jane H. Christensen, et al. · Genome Medicine · 35

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Acquired mutations and transcriptional remodeling in long-term estrogen-deprived locoregional breast cancer recurrences

2021 · Nolan Priedigkeit, Kai Ding, et al. · Breast Cancer Research · 32

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Cocaine Administration and Its Withdrawal Enhance the Expression of Genes Encoding Histone-Modifying Enzymes and Histone Acetylation in the Rat Prefrontal Cortex

2017 · Anna Sadakierska-Chudy, Małgorzata Frankowska, et al. · Neurotoxicity Research · 31

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Gene Isoform Specificity through Enhancer-Associated Antisense Transcription

2012 · Courtney S. Onodera, Jason G. Underwood, et al. · PLoS ONE · 30

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The Schizophrenia-Associated BRD1 Gene Regulates Behavior, Neurotransmission, and Expression of Schizophrenia Risk Enriched Gene Sets in Mice

2016 · Per Qvist, Jane Hvarregaard Christensen, et al. · Biological Psychiatry · 27

NIT2 dampens BRD1 phase separation and restrains oxidative phosphorylation to enhance chemosensitivity in gastric cancer

2024 · Ziyang Wang, Yuqin Di, et al. · Science Translational Medicine · 26

The Schizophrenia and Bipolar Disorder associated BRD1 gene is regulated upon chronic restraint stress

2012 · Jane H. Christensen, Betina Elfving, et al. · European Neuropsychopharmacology · 26

In silico design and molecular basis for the selectivity of Olinone toward the first over the second bromodomain of BRD4

2019 · Yoel Rodríguez, Guillermo Gerona‐Navarro, et al. · Proteins Structure Function and Bioinformatics · 25

CD4+ tissue-resident memory Th17 cells are a major source of IL-17A in Spondyloarthritis synovial tissue

2025 · Feng Liu, Hui Shi, et al. · Annals of the Rheumatic Diseases · 23

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Works count: 484

Citation count: 2,154