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Keyword

BRD9

Description: BRD9 is a human protein-coding gene whose protein product participates in chromatin regulation and gene expression.
Wikidata ID: wiki/Q18045886
OpenAlex ID: keywords/brd9
Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy
2013 · Cigall Kadoch, Diana C Hargreaves, et al. · Nature Genetics · 1,459
A non-canonical SWI/SNF complex is a synthetic lethal target in cancers driven by BAF complex perturbation
2018 · Brittany C. Michel, Andrew R. D’Avino, et al. · Nature Cell Biology · 423
The mutational landscape of cutaneous T cell lymphoma and Sézary syndrome
2015 · Ana Carolina da Silva Almeida, Francesco Abate, et al. · Nature Genetics · 379
Iterative Design and Optimization of Initially Inactive Proteolysis Targeting Chimeras (PROTACs) Identify VZ185 as a Potent, Fast, and Selective von Hippel–Lindau (VHL) Based Dual Degrader Probe of BRD9 and BRD7
2018 · Vittoria Zoppi, Scott J. Hughes, et al. · Journal of Medicinal Chemistry · 325
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Degradation of the BAF Complex Factor BRD9 by Heterobifunctional Ligands
2017 · David Remillard, Dennis L. Buckley, et al. · Angewandte Chemie International Edition · 290
Discovery of I-BRD9, a Selective Cell Active Chemical Probe for Bromodomain Containing Protein 9 Inhibition
2015 · Natalie H. Theodoulou, Paul Bamborough, et al. · Journal of Medicinal Chemistry · 235
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Spliceosomal disruption of the non-canonical BAF complex in cancer
2019 · Daichi Inoue, Guo-Liang Chew, et al. · Nature · 230
Glioma tumor suppressor candidate region gene 1 (GLTSCR1) and its paralog GLTSCR1-like form SWI/SNF chromatin remodeling subcomplexes
2018 · Aktan Alpsoy, Emily C. Dykhuizen · Journal of Biological Chemistry · 228
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Structure-Based Design of an in Vivo Active Selective BRD9 Inhibitor
2016 · Laetitia J. Martin, Manfred Koegl, et al. · Journal of Medicinal Chemistry · 224
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A Subset of Human Bromodomains Recognizes Butyryllysine and Crotonyllysine Histone Peptide Modifications
2015 · E. Megan Flynn, Oscar W. Huang, et al. · Structure · 220
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Targeted degradation of BRD9 reverses oncogenic gene expression in synovial sarcoma
2018 · Gerard L Brien, David Remillard, et al. · eLife · 215
A non-canonical BRD9-containing BAF chromatin remodeling complex regulates naive pluripotency in mouse embryonic stem cells
2018 · Jovylyn Gatchalian, Shivani Malik, et al. · Nature Communications · 214
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BRD9 defines a SWI/SNF sub-complex and constitutes a specific vulnerability in malignant rhabdoid tumors
2019 · Xiaofeng Wang, Su Wang, et al. · Nature Communications · 213
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Vitamin D Switches BAF Complexes to Protect β Cells
2018 · Zong Wei, Eiji Yoshihara, et al. · Cell · 207
Sensitivity and engineered resistance of myeloid leukemia cells to BRD9 inhibition
2016 · Anja F Hohmann, Laetitia J Martin, et al. · Nature Chemical Biology · 181
LP99: Discovery and Synthesis of the First Selective BRD7/9 Bromodomain Inhibitor
2015 · Peter G. K. Clark, Lucas C. C. Vieira, et al. · Angewandte Chemie International Edition · 164
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High-performance CRISPR-Cas12a genome editing for combinatorial genetic screening
2020 · Rodrigo A. Gier, Krista A. Budinich, et al. · Nature Communications · 133
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LP99: Discovery and Synthesis of the First Selective BRD7/9 Bromodomain Inhibitor
2015 · Peter G. K. Clark, Lucas C. C. Vieira, et al. · Angewandte Chemie · 122
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A Genome-wide CRISPR Screen Reveals a Role for the Non-canonical Nucleosome-Remodeling BAF Complex in Foxp3 Expression and Regulatory T Cell Function
2020 · Chin-San Loo, Jovylyn Gatchalian, et al. · Immunity · 121
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Diving into the Water: Inducible Binding Conformations for BRD4, TAF1(2), BRD9, and CECR2 Bromodomains
2016 · Terry D. Crawford, Vickie Tsui, et al. · Journal of Medicinal Chemistry · 112
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DCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic- and acquired-degrader resistance
2024 · Martin Schröder, Martin Renatus, et al. · Nature Communications · 98
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[1,2,4]Triazolo[4,3-a]phthalazines: Inhibitors of Diverse Bromodomains
2013 · Oleg Fedorov, Hannah Lingard, et al. · Journal of Medicinal Chemistry · 97
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Biological function and histone recognition of family IV bromodomain‐containing proteins
2017 · Jonathan T. Lloyd, Karen C. Glass · Journal of Cellular Physiology · 83
Merkel cell polyomavirus activates LSD1-mediated blockade of non-canonical BAF to regulate transformation and tumorigenesis
2020 · Donglim Esther Park, Jingwei Cheng, et al. · Nature Cell Biology · 79
miR-140-3p functions as a tumor suppressor in squamous cell lung cancer by regulating BRD9
2019 · Haitao Huang, Yuxuan Wang, et al. · Cancer Letters · 77
Works count: 578
Citation count: 9,278
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