Keyword

CA125

Description: CA125, also known as MUC16, is a cell-surface mucin protein used as a tumor marker in cancer diagnosis and monitoring.

Primary topic: Ovarian cancer diagnosis and treatment (43%)

Wikidata ID: wiki/Q1032902

OpenAlex ID: keywords/ca125

A Radioimmunoassay Using a Monoclonal Antibody to Monitor the Course of Epithelial Ovarian Cancer

1983 · Robert C. Bast, Thomas L. Klug, et al. · New England Journal of Medicine · 2,136

Novel Molecular Subtypes of Serous and Endometrioid Ovarian Cancer Linked to Clinical Outcome

2008 · Richard W. Tothill, Anna V. Tinker, et al. · Clinical Cancer Research · 1,468

Diagnosis of pancreatic cystic neoplasms: a report of the cooperative pancreatic cyst study

2004 · William R. Brugge, Kent Lewandrowski, et al. · Gastroenterology · 1,386

Site-specific conjugation of a cytotoxic drug to an antibody improves the therapeutic index

2008 · Jagath R Junutula, Helga Raab, et al. · Nature Biotechnology · 1,383

Effect of Screening on Ovarian Cancer Mortality

2011 · Saundra S. Buys · JAMA · 1,326

Mucins in the mucosal barrier to infection

2008 · S K Linden, P Sutton, et al. · Mucosal Immunology · 1,236

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Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer

2017 · Australian Pancreatic Cancer Genome Initiative, Vinod P. Balachandran, et al. · Nature · 1,187

National Academy of Clinical Biochemistry Laboratory Medicine Practice Guidelines for Use of Tumor Markers in Testicular, Prostate, Colorectal, Breast, and Ovarian Cancers

2008 · Catharine M Sturgeon, Michael J Duffy, et al. · Clinical Chemistry · 1,130

Ovarian cancer screening and mortality in the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS): a randomised controlled trial

2015 · Ian J Jacobs, Usha Menon, et al. · The Lancet · 1,045

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Design of the prostate, lung, colorectal and ovarian (PLCO) cancer screening trial

2000 · Philip C. Prorok, Gerald L. Andriole, et al. · Controlled Clinical Trials · 1,037

Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients

2003 · F. Stephen Hodi, Martin C. Mihm, et al. · Proceedings of the National Academy of Sciences · 1,007

Implementing an online tool for genome-wide validation of survival-associated biomarkers in ovarian-cancer using microarray data from 1287 patients

2012 · Balázs Győrffy, András Lánczky, et al. · Endocrine Related Cancer · 970

A risk of malignancy index incorporating CA 125, ultrasound and menopausal status for the accurate preoperative diagnosis of ovarian cancer

1990 · I. JACOBS, D. ORAM, et al. · BJOG An International Journal of Obstetrics & Gynaecology · 962

The CA 125 tumour-associated antigen: a review of the literature

1989 · Ian Jacobs, Robert C. Bast · Human Reproduction · 956

Three Biomarkers Identified from Serum Proteomic Analysis for the Detection of Early Stage Ovarian Cancer

2004 · Zhen Zhang, Robert C. Bast, et al. · Cancer Research · 934

A novel multiple marker bioassay utilizing HE4 and CA125 for the prediction of ovarian cancer in patients with a pelvic mass

2008 · Richard G. Moore, D. Scott McMeekin, et al. · Gynecologic Oncology · 875

Sensitivity and specificity of multimodal and ultrasound screening for ovarian cancer, and stage distribution of detected cancers: results of the prevalence screen of the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS)

2009 · Usha Menon, Aleksandra Gentry-Maharaj, et al. · The Lancet Oncology · 829

Ovarian Carcinoma Subtypes Are Different Diseases: Implications for Biomarker Studies

2008 · Martin Köbel, Steve E Kalloger, et al. · PLoS Medicine · 814

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Structure and Function of the Cell Surface (Tethered) Mucins

2007 · Christine L. Hattrup, Sandra J. Gendler · Annual Review of Physiology · 779

Recent progress in the diagnosis and treatment of ovarian cancer

2011 · Danijela Jelovac, Deborah K. Armstrong · CA A Cancer Journal for Clinicians · 765

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Overexpression of HER-2/neu is associated with poor survival in advanced epithelial ovarian cancer.

1990 · A Berchuck, A Kamel, et al. · PubMed · 760

The use of multiple novel tumor biomarkers for the detection of ovarian carcinoma in patients with a pelvic mass

2007 · Richard G. Moore, Amy K. Brown, et al. · Gynecologic Oncology · 695

A microfluidic ExoSearch chip for multiplexed exosome detection towards blood-based ovarian cancer diagnosis

2015 · Zheng Zhao, Yang Yang, et al. · Lab on a Chip · 684

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The detection of differentially expressed microRNAs from the serum of ovarian cancer patients using a novel real-time PCR platform

2008 · Kimberly E. Resnick, Hansjuerg Alder, et al. · Gynecologic Oncology · 647

Lysophosphatidic Acid as a Potential Biomarker for Ovarian and Other Gynecologic Cancers

1998 · Yan Xu · JAMA · 637

Works count: 28,740

Citation count: 372,900