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Keyword

CagA

Description: A virulence protein produced by Helicobacter pylori that contributes to bacterial pathogenicity and host-cell effects.
OpenAlex ID: keywords/caga
Pathogenesis of Helicobacter pylori Infection
2006 · Johannes G. Kusters, Arnoud H. M. van Vliet, et al. · Clinical Microbiology Reviews · 2,526
cag , a pathogenicity island of Helicobacter pylori, encodes type I-specific and disease-associated virulence factors
1996 · Stefano Censini, Christina Lange, et al. · Proceedings of the National Academy of Sciences · 1,872
Infection with Helicobacter pylori strains possessing cagA is associated with an increased risk of developing adenocarcinoma of the stomach.
1995 · M J Blaser, G I Perez-Perez, et al. · PubMed · 1,609
Mosaicism in Vacuolating Cytotoxin Alleles of Helicobacter pylori
1995 · John C. Atherton, Ping Cao, et al. · Journal of Biological Chemistry · 1,567
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Translocation of Helicobacter pylori CagA into Gastric Epithelial Cells by Type IV Secretion
2000 · Stefan Odenbreit, Jürgen Püls, et al. · Science · 1,286
Molecular characterization of the 128-kDa immunodominant antigen of Helicobacter pylori associated with cytotoxicity and duodenal ulcer.
1993 · A Covacci, S Censini, et al. · Proceedings of the National Academy of Sciences · 1,248
SHP-2 Tyrosine Phosphatase as an Intracellular Target of Helicobacter pylori CagA Protein
2002 · Hideaki Higashi, Ryouhei Tsutsumi, et al. · Science · 1,030
Modelling human development and disease in pluripotent stem-cell-derived gastric organoids
2014 · Kyle W. McCracken, Emily M. Catá, et al. · Nature · 977
Risk for gastric cancer in people with CagA positive or CagA negative Helicobacter pylori infection.
1997 · J Parsonnet, G D Friedman, et al. · Gut · 959
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A standardized mouse model of Helicobacter pylori infection: Introducing the Sydney strain
1997 · A Lee, J O'Rourke, et al. · Gastroenterology · 937
Altered states: Involvement of phosphorylated CagA in the induction of host cellular growth changes by Helicobacter pylori
1999 · E. D. Segal, J. Cha, et al. · Proceedings of the National Academy of Sciences · 770
Oncogenic mechanisms of the Helicobacter pylori CagA protein
2004 · Masanori Hatakeyama · Nature reviews. Cancer · 753
Disruption of the Epithelial Apical-Junctional Complex by Helicobacter pylori CagA
2003 · Manuel R. Amieva, Roger Vogelmann, et al. · Science · 741
Analyses of the cag pathogenicity island of Helicobacter pylori
1998 · Natalia S. Akopyants, Sandra W. Clifton, et al. · Molecular Microbiology · 725
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Mechanisms of disease: Helicobacter pylori virulence factors
2010 · Yoshio Yamaoka · Nature Reviews Gastroenterology & Hepatology · 668
Life in the human stomach: persistence strategies of the bacterial pathogen Helicobacter pylori
2013 · Nina R. Salama, Mara L. Hartung, et al. · Nature Reviews Microbiology · 666
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Helicobacter pylori and Interleukin 1 Genotyping: An Opportunity to Identify High-Risk Individuals for Gastric Carcinoma
2002 · C. Figueiredo · JNCI Journal of the National Cancer Institute · 625
Helicobacter exploits integrin for type IV secretion and kinase activation
2007 · Terry Kwok, Dana Zabler, et al. · Nature · 619
Clinical relevance of the cagA, vacA, and iceA status of Helicobacter pylori
1998 · Leen–Jan van Doorn, Céu Figueiredo, et al. · Gastroenterology · 612
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Clinical relevance of the Helicobacter pylori gene for blood-group antigen-binding adhesin
1999 · Markus Gerhard, Norbert Lehn, et al. · Proceedings of the National Academy of Sciences · 610
Helicobacter pylori and Atrophic Gastritis: Importance of the cagA Status
1995 · E. J. Kuipers, G. I. Perez-Perez, et al. · JNCI Journal of the National Cancer Institute · 596
Transgenic expression of Helicobacter pylori CagA induces gastrointestinal and hematopoietic neoplasms in mouse
2008 · Naomi Ohnishi, Hitomi Yuasa, et al. · Proceedings of the National Academy of Sciences · 594
Analysis of expression of CagA and VacA virulence factors in 43 strains of Helicobacter pylori reveals that clinical isolates can be divided into two major types and that CagA is not necessary for expression of the vacuolating cytotoxin
1995 · Z Xiang, S Censini, et al. · Infection and Immunity · 586
Tyrosine phosphorylation of the Helicobacter pylori CagA antigen after cag -driven host cell translocation
2000 · Markus Stein, Rino Rappuoli, et al. · Proceedings of the National Academy of Sciences · 581
Biological activity of the Helicobacter pylori virulence factor CagA is determined by variation in the tyrosine phosphorylation sites
2002 · Hideaki Higashi, Ryouhei Tsutsumi, et al. · Proceedings of the National Academy of Sciences · 579
Works count: 6,158
Citation count: 154,300
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