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Keyword

CAIX

Description: A shorthand designation used for carbonic anhydrase IX in biomedical research and for calcium ion in spectroscopic notation; its meaning depends on context.
OpenAlex ID: keywords/caix
Hypoxia in cancer: significance and impact on clinical outcome
2007 · Peter Vaupel, Arnulf Mayer · Cancer and Metastasis Reviews · 2,231
Treatment of Metastatic Renal Cell Carcinoma With CAIX CAR-engineered T cells: Clinical Evaluation and Management of On-target Toxicity
2013 · Cor HJ Lamers, Stefan Sleijfer, et al. · Molecular Therapy · 704
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Structure-based drug discovery of carbonic anhydrase inhibitors
2012 · Claudiu T. Supuran · Journal of Enzyme Inhibition and Medicinal Chemistry · 614
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Activity of the Monocarboxylate Transporter 1 Inhibitor AZD3965 in Small Cell Lung Cancer
2013 · Radosław Polański, Cassandra L. Hodgkinson, et al. · Clinical Cancer Research · 373
Diagnostic, prognostic and therapeutic implications of carbonic anhydrases in cancer
2003 · C P S Potter, A L Harris · British Journal of Cancer · 300
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Carbonic Anhydrases: Role in pH Control and Cancer
2018 · Mam Mboge, Brian Mahon, et al. · Metabolites · 281
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Darwinian Dynamics of Intratumoral Heterogeneity: Not Solely Random Mutations but Also Variable Environmental Selection Forces
2016 · Mark C. Lloyd, Jessica J. Cunningham, et al. · Cancer Research · 249
The role of carbonic anhydrases in renal physiology
2006 · J.M. Purkerson, G.J. Schwartz · Kidney International · 248
Sulfocoumarins (1,2-Benzoxathiine-2,2-dioxides): A Class of Potent and Isoform-Selective Inhibitors of Tumor-Associated Carbonic Anhydrases
2012 · Kaspars Tars, Daniela Vullo, et al. · Journal of Medicinal Chemistry · 221
Xp11 Translocation Renal Cell Carcinoma (RCC): Extended Immunohistochemical Profile Emphasizing Novel RCC Markers
2010 · Pedram Argani, Jessica Hicks, et al. · The American Journal of Surgical Pathology · 214
Carbonic anhydrase inhibitors. Inhibition of the transmembrane isozyme XII with sulfonamides—a new target for the design of antitumor and antiglaucoma drugs?
2005 · Daniela Vullo, Alessio Innocenti, et al. · Bioorganic & Medicinal Chemistry Letters · 214
Metabolic markers in relation to hypoxia; staining patterns and colocalization of pimonidazole, HIF-1α, CAIX, LDH-5, GLUT-1, MCT1 and MCT4
2011 · Saskia E Rademakers, Jasper Lok, et al. · BMC Cancer · 210
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Sulfamates and their therapeutic potential
2004 · Jean‐Yves Winum, Andrea Scozzafava, et al. · Medicinal Research Reviews · 206
Synthesis and Carbonic Anhydrase Isoenzymes I, II, IX, and XII Inhibitory Effects of Dimethoxybromophenol Derivatives Incorporating Cyclopropane Moieties
2014 · Murat Boztaş, Yasin Çetinkaya, et al. · Journal of Medicinal Chemistry · 200
Carbonic Anhydrases and Metabolism
2018 · Claudiu Supuran · Metabolites · 198
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Cytogenetic and Molecular Tumor Profiling for Type 1 and Type 2 Papillary Renal Cell Carcinoma
2009 · Tobias Klatte, Allan J. Pantuck, et al. · Clinical Cancer Research · 186
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Carbonic Anhydrase Inhibitors Targeting Metabolism and Tumor Microenvironment
2020 · Andrea Angeli, Fabrizio Carta, et al. · Metabolites · 178
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Treatment of metastatic renal cell carcinoma (mRCC) with CAIX CAR-engineered T-cells–a completed study overview
2016 · Cor H.J. Lamers, Yarne Klaver, et al. · Biochemical Society Transactions · 168
Tumor‐associated Carbonic Anhydrases and Their Clinical Significance
2006 · Silvia Pastorekova, Seppo Parkkila, et al. · Advances in clinical chemistry · 162
Dynamics of Tumor Hypoxia Measured with Bioreductive Hypoxic Cell Markers
2007 · Anna S. E. Ljungkvist, Johan Bussink, et al. · Radiation Research · 160
MN/CA IX/G250 as a potential target for immunotherapy of renal cell carcinomas
1999 · H Uemura, Y Nakagawa, et al. · British Journal of Cancer · 158
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The renal cell carcinoma-associated antigen G250 encodes a human leukocyte antigen (HLA)-A2.1-restricted epitope recognized by cytotoxic T lymphocytes.
1999 · J L Vissers, I J De Vries, et al. · PubMed · 135
Hypoxia-inducible factor-1α mRNA: a new target for destabilization by tristetraprolin in endothelial cells
2011 · Sandrine Chamboredon, Delphine Ciais, et al. · Molecular Biology of the Cell · 126
The cellular physiology of carbonic anhydrases.
2001 · S Breton · PubMed · 124
Carbonic anhydrase inhibitors. Inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, IX, and XII with Schiff’s bases incorporating chromone and aromatic sulfonamide moieties, and their zinc complexes
2005 · Luca Puccetti, Giuseppe Fasolis, et al. · Bioorganic & Medicinal Chemistry Letters · 121
Works count: 1,022
Citation count: 19,800
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