Keyword

CAPNS1

Description: CAPNS1 is a human protein-coding gene that encodes the small regulatory subunit of calpain proteases, studied in cancer and cellular processes.

Primary topic: Calpain Protease Function and Regulation (35%)

Wikidata ID: wiki/Q17855822

OpenAlex ID: keywords/capns1

Calpain is required for macroautophagy in mammalian cells

2006 · Francesca Demarchi, Cosetta Bertoli, et al. · The Journal of Cell Biology · 156

Inhibition of microvesiculation sensitizes prostate cancer cells to chemotherapy and reduces docetaxel dose required to limit tumor growth in vivo

2015 · Samireh Jorfi, Ephraim A. Ansa-Addo, et al. · Scientific Reports · 96

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Differential profiling of human red blood cells during storage for 52 selected microRNAs

2010 · Meganathan Kannan, Chintamani Atreya · Transfusion · 79

The Calpain System as a Modulator of Stress/Damage Response

2007 · Claudio Schneider, Francesca Demarchi · Cell Cycle · 78

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MiR-99a and MiR-491 Regulate Cisplatin Resistance in Human Gastric Cancer Cells by Targeting CAPNS1

2016 · Yajie Zhang, Wenxia Xu, et al. · International Journal of Biological Sciences · 73

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Calcium-dependent plasma membrane repair requires m- or μ-calpain, but not calpain-3, the proteasome, or caspases

2009 · Ronald L. Mellgren, Katsuya Miyake, et al. · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · 69

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Accelerated protein evolution analysis reveals genes and pathways associated with the evolution of mammalian longevity

2011 · Yang Li, João Pedro de Magalhães · AGE · 61

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Calpain small-1 modulates Akt/FoxO3A signaling and apoptosis through PP2A

2008 · C Bertoli, T Copetti, et al. · Oncogene · 61

Proteomics study of serum exosomes from papillary thyroid cancer patients

2018 · Dan Luo, Shaohua Zhan, et al. · Endocrine Related Cancer · 59

Endoplasmic reticulum stress-induced complex I defect: Central role of calcium overload

2020 · Ahmed A. Mohsin, Jeremy Thompson, et al. · Archives of Biochemistry and Biophysics · 52

Selective deletion of endothelial cell calpain in mice reduces diabetic cardiomyopathy by improving angiogenesis

2019 · Xiaomei Teng, Chen Ji, et al. · Diabetologia · 49

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Receptor-Interacting Protein 140 Orchestrates the Dynamics of Macrophage M1/M2 Polarization

2015 · Yi-Wei Lin, Bomi Lee, et al. · Journal of Innate Immunity · 43

Whole Genome Expression Analyses of miRNAs and mRNAs Suggest the Involvement of miR-320a and miR-155-3p and their Targeted Genes in Lithium Response in Bipolar Disorder

2019 · Claudia Pisanu, Eleni Merkouri Papadima, et al. · International Journal of Molecular Sciences · 42

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Targeted inhibition of endothelial calpain delays wound healing by reducing inflammation and angiogenesis

2020 · Chenlong Yi, Weihua Wu, et al. · Cell Death and Disease · 40

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Calpain as a Novel Regulator of Autophagosome Formation

2007 · Francesca Demarchi, Cosetta Bertoli, et al. · Autophagy · 40

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Characterization and comparative expression of zebrafish calpain system genes during early development

2008 · Stephanie E. Lepage, Ashley E.E. Bruce · Developmental Dynamics · 39

Fetuin A Stabilizes m-Calpain and Facilitates Plasma Membrane Repair

2007 · Ronald L. Mellgren, Xinhua Huang · Journal of Biological Chemistry · 33

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Calpain activation mediates microgravity-induced myocardial abnormalities in mice via p38 and ERK1/2 MAPK pathways

2020 · Liwen Liang, Huili Li, et al. · Journal of Biological Chemistry · 32

Tamoxifen increases nuclear respiratory factor 1 transcription by activating estrogen receptor β and AP‐1 recruitment to adjacent promoter binding sites

2011 · Margarita M. Ivanova, Kristen H. Luken, et al. · The FASEB Journal · 32

CAPNS1 Regulates USP1 Stability and Maintenance of Genome Integrity

2013 · Francesca Cataldo, Leticia Y. Peche, et al. · Molecular and Cellular Biology · 30

miR‐203 inhibits augmented proliferation and metastasis of hepatocellular carcinoma residual in the promoted regenerating liver

2017 · Xiao‐Bo Zheng, Xiao‐Bo Chen, et al. · Cancer Science · 29

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Loss of calpains-1 and -2 prevents repair of plasma membrane scrape injuries, but not small pores, and induces a severe muscular dystrophy

2020 · Ann-Katrin Piper, Reece A. Sophocleous, et al. · American Journal of Physiology-Cell Physiology · 28

Association of PPARGC1A and CAPNS1 gene polymorphisms and expression with meat quality traits in pigs

2011 · G. Gandolfi, M.U. Cinar, et al. · Meat Science · 28

NRF-1, and AP-1 regulate the promoter of the human calpain small subunit 1 (CAPNS1) gene

2007 · Irfan A. Asangani, Suhail A.K. Rasheed, et al. · Gene · 27

2022 · Wen Ye, Zhehao Shi, et al. · Frontiers in Oncology · 26

Works count: 116

Citation count: 1,710