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Keyword

CYR61

Description: A human protein-coding gene, also known as CCN1, that encodes a matricellular signaling protein involved in cell growth and tissue remodeling.
Wikidata ID: wiki/Q18027691
OpenAlex ID: keywords/ccn1
The matricellular protein CCN1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healing
2010 · Joon-Il Jun, Lester F. Lau · Nature Cell Biology · 996
Connective tissue growth factor: a mediator of TGF-β action on fibroblasts
1997 · Gary R. Grotendorst · Cytokine & Growth Factor Reviews · 761
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The modular architecture of a new family of growth regulators related to connective tissue growth factor
1993 · Peer Bork · FEBS Letters · 627
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The Connective Tissue Growth Factor/Cysteine- Rich 61/Nephroblastoma Overexpressed (CCN) Family
1999 · David R. Brigstock · Endocrine Reviews · 590
Functions and mechanisms of action of CCN matricellular proteins
2008 · Chih-Chiun Chen, Lester F. Lau · The International Journal of Biochemistry & Cell Biology · 549
Id Genes Are Direct Targets of Bone Morphogenetic Protein Induction in Embryonic Stem Cells
1999 · Angela Hollnagel, Verena Oehlmann, et al. · Journal of Biological Chemistry · 527
The CCN family: a new stimulus package
2003 · DR Brigstock · Journal of Endocrinology · 502
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CYR61, a product of a growth factor-inducible immediate early gene, promotes angiogenesis and tumor growth
1998 · Alexander M. Babic, Maria L. Kireeva, et al. · Proceedings of the National Academy of Sciences · 495
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Flow-dependent YAP/TAZ activities regulate endothelial phenotypes and atherosclerosis
2016 · Kuei-Chun Wang, Yi-Ting Yeh, et al. · Proceedings of the National Academy of Sciences · 467
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Fisp12/Mouse Connective Tissue Growth Factor Mediates Endothelial Cell Adhesion and Migration through Integrin α v β 3 , Promotes Endothelial Cell Survival, and Induces Angiogenesis In Vivo
1999 · Alexander M. Babic, Chih-Chiun Chen, et al. · Molecular and Cellular Biology · 450
Yes-associated protein (YAP) transcriptional coactivator functions in balancing growth and differentiation in skin
2011 · Haiying Zhang, H. Amalia Pasolli, et al. · Proceedings of the National Academy of Sciences · 419
CYR61 (CCN1) Is Essential for Placental Development and Vascular Integrity
2002 · Fan-E Mo, Andrew G. Muntean, et al. · Molecular and Cellular Biology · 417
Taxol Resistance in Breast Cancer Cells Is Mediated by the Hippo Pathway Component TAZ and Its Downstream Transcriptional TargetsCyr61andCTGF
2011 · Dulcie Lai, King Ching Ho, et al. · Cancer Research · 416
Identification of eukaryotic mRNAs that are translated at reduced cap binding complex eIF4F concentrations using a cDNA microarray
1999 · Gregg Johannes, Mark S. Carter, et al. · Proceedings of the National Academy of Sciences · 394
Hippo Pathway-independent Restriction of TAZ and YAP by Angiomotin
2011 · Siew Wee Chan, Chun Jye Lim, et al. · Journal of Biological Chemistry · 386
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NOV (nephroblastoma overexpressed) and the CCN family of genes: structural and functional issues
2001 · B Perbal · Molecular Pathology · 348
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Identification of a family of low-affinity insulin-like growth factor binding proteins (IGFBPs): Characterization of connective tissue growth factor as a member of the IGFBP superfamily
1997 · Ho-Seong Kim, Srinivasa R. Nagalla, et al. · Proceedings of the National Academy of Sciences · 347
Cyr61, a Product of a Growth Factor-Inducible Immediate-Early Gene, Promotes Cell Proliferation, Migration, and Adhesion
1996 · Maria L. Kireeva, Fan-E Mo, et al. · Molecular and Cellular Biology · 340
CCN1/CYR61: the very model of a modern matricellular protein
2011 · Lester F. Lau · Cellular and Molecular Life Sciences · 334
Comprehensive gene expression profiles reveal pathways related to the pathogenesis of chronic obstructive pulmonary disease
2004 · Wen Ning, Chao-Jun Li, et al. · Proceedings of the National Academy of Sciences · 329
Fructose stimulated de novo lipogenesis is promoted by inflammation
2020 · Jelena Todoric, Giuseppe Di Caro, et al. · Nature Metabolism · 328
Expression of cyr61, a Growth Factor-Inducible Immediate-Early Gene
1990 · T P O'Brien, G P Yang, et al. · Molecular and Cellular Biology · 312
The Angiogenic Factors Cyr61 and Connective Tissue Growth Factor Induce Adhesive Signaling in Primary Human Skin Fibroblasts
2001 · Chih-Chiun Chen, Ningyu Chen, et al. · Journal of Biological Chemistry · 305
The Angiogenic Factor Cyr61 Activates a Genetic Program for Wound Healing in Human Skin Fibroblasts
2001 · Chih-Chiun Chen, Fan-E Mo, et al. · Journal of Biological Chemistry · 300
Elevated levels of connective tissue growth factor, WISP-1, and CYR61 in primary breast cancers associated with more advanced features.
2001 · D Xie, K Nakachi, et al. · PubMed · 298
Works count: 2,649
Citation count: 57,150
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