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Keyword

CCN4

Description: A secreted signaling protein, also called WISP1, involved in processes including cell growth, migration, adhesion, and tissue development.
OpenAlex ID: keywords/ccn4
CCN Proteins - A New Family of Cell Growth and Differentiation Regulators
2005 · Perbal, Bernard V., Takigawa, Masaharu · IMPERIAL COLLEGE PRESS eBooks · 134
WISP1 Is a Novel Adipokine Linked to Inflammation in Obesity
2014 · Veronica Murahovschi, Olga Pivovarova, et al. · Diabetes · 130
Emerging role of CCN family proteins in tumorigenesis and cancer metastasis (Review)
2015 · JUN LI, LIN YE, et al. · International Journal of Molecular Medicine · 119
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CCN4/WISP1 (WNT1 inducible signaling pathway protein 1): A focus on its role in cancer
2015 · Irem Gurbuz, Ruth Chiquet-Ehrismann · The International Journal of Biochemistry & Cell Biology · 99
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WNT1-induced Secreted Protein-1 (WISP1), a Novel Regulator of Bone Turnover and Wnt Signaling
2015 · Azusa Maeda, Mitsuaki Ono, et al. · Journal of Biological Chemistry · 93
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The CCN proteins: important signaling mediators in stem cell differentiation and tumorigenesis.
2010 · Guo-Wei Zuo, Christopher D Kohls, et al. · PubMed · 87
Differential roles of CCN family proteins during osteoblast differentiation: Involvement of Smad and MAPK signaling pathways
2011 · Harumi Kawaki, Satoshi Kubota, et al. · Bone · 84
CCN4/WISP1 controls cutaneous wound healing by modulating proliferation, migration and ECM expression in dermal fibroblasts via α5β1 and TNFα
2018 · Mitsuaki Ono, Asuka Masaki, et al. · Matrix Biology · 78
Novel applications of trophic factors, Wnt and WISP for neuronal repair and regeneration in metabolic disease
2015 · Kenneth Maiese · Neural Regeneration Research · 77
CCN4 induces IL-6 production through αvβ5 receptor, PI3K, Akt, and NF-κB singling pathway in human synovial fibroblasts
2013 · Chun-Han Hou, Chih-Hsin Tang, et al. · Arthritis Research & Therapy · 73
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Picking a bone with WISP1 (CCN4): new strategies against degenerative joint disease
2016 · Kenneth Maiese · Journal of Translational Science · 71
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The CCN family acting throughout the body: recent research developments
2013 · Satoshi Kubota, Masaharu Takigawa · BioMolecular Concepts · 69
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Wnt1 Inducible Signaling Pathway Protein 1 (WISP1) Targets PRAS40 to Govern β-Amyloid Apoptotic Injury of Microglia
2012 · Yan Chen Shang, Zhao Zhong Chong, et al. · Current Neurovascular Research · 66
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WISP-1, a novel angiogenic regulator of the CCN family, promotes oral squamous cell carcinoma angiogenesis through VEGF-A expression
2015 · Jing-Yuan Chuang, Po-Chun Chen, et al. · Oncotarget · 62
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Tuberous Sclerosis Protein 2 (TSC2) Modulates CCN4 Cytoprotection During Apoptotic Amyloid Toxicity in Microglia
2013 · Yan Chen Shang, Zhao Zhong Chong, et al. · Current Neurovascular Research · 61
Wnt2 and WISP-1/CCN4 Induce Intimal Thickening via Promotion of Smooth Muscle Cell Migration
2016 · Helen Williams, Carina A.E. Mill, et al. · Arteriosclerosis Thrombosis and Vascular Biology · 58
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CCN4 Regulates Vascular Smooth Muscle Cell Migration and Proliferation
2013 · Hao Liu, Wenpeng Dong, et al. · Molecules and Cells · 57
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Wisp1 is a circulating factor that stimulates proliferation of adult mouse and human beta cells
2020 · Rebeca Fernandez-Ruiz, Ainhoa García-Alamán, et al. · Nature Communications · 56
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The tumor cell‐secreted matricellular protein WISP1 drives pro‐metastatic collagen linearization
2019 · Hong Jia, Jagadeesh Janjanam, et al. · The EMBO Journal · 51
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Expression and physiological role of CCN4/Wnt‐induced secreted protein 1 mRNA splicing variants in chondrocytes
2007 · Takeshi Yanagita, Satoshi Kubota, et al. · FEBS Journal · 49
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Engineering c-Met-CAR NK-92 cells as a promising therapeutic candidate for lung adenocarcinoma
2023 · Yan Peng, Wenqing Zhang, et al. · Pharmacological Research · 48
Spatial-temporal modulation of CCN proteins during wound healing in human skin in vivo
2011 · Laure Rittié, Bernard Perbal, et al. · Journal of Cell Communication and Signaling · 47
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WISP1/CCN4 aggravates cartilage degeneration in experimental osteoarthritis
2017 · M.H. van den Bosch, A.B. Blom, et al. · Osteoarthritis and Cartilage · 46
Anti-fibrotic effect of CCN3 accompanied by altered gene expression profile of the CCN family
2012 · Tarek Abd El Kader, Satoshi Kubota, et al. · Journal of Cell Communication and Signaling · 46
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Proteins on the catwalk: modelling the structural domains of the CCN family of proteins
2009 · Kenneth P. Holbourn, Bernard Perbal, et al. · Journal of Cell Communication and Signaling · 45
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Works count: 144
Citation count: 2,728
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