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Keyword

CCN6

Description: A secreted signaling protein, also called WISP3, involved in regulating cell growth and tissue development and studied in cancer biology.
OpenAlex ID: keywords/ccn6
Quantitative proteomic landscape of metaplastic breast carcinoma pathological subtypes and their relationship to triple-negative tumors
2020 · Sabra I. Djomehri, Maria E. Gonzalez, et al. · Nature Communications · 144
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Matricellular Proteins: A Sticky Affair with Cancers
2012 · Han Chung Chong, Chek Kun Tan, et al. · Journal of Oncology · 139
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CCN Proteins - A New Family of Cell Growth and Differentiation Regulators
2005 · Perbal, Bernard V., Takigawa, Masaharu · IMPERIAL COLLEGE PRESS eBooks · 134
Pancreatic cancer: A comprehensive review and update
2013 · Thiruvengadam Muniraj, Priya A. Jamidar, et al. · Disease-a-Month · 130
Bone morphogenetic proteins (BMPs): From morphogens to metabologens
2009 · A. Hari Reddi, A. Hari Reddi, et al. · Cytokine & Growth Factor Reviews · 120
Emerging role of CCN family proteins in tumorigenesis and cancer metastasis (Review)
2015 · JUN LI, LIN YE, et al. · International Journal of Molecular Medicine · 119
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WISP3 (CCN6) Is a Secreted Tumor-Suppressor Protein that Modulates IGF Signaling in Inflammatory Breast Cancer
2004 · Celina G. Kleer, Yanhong Zhang, et al. · Neoplasia · 92
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Metaplastic Breast Carcinoma: Update on Histopathology and Molecular Alterations
2019 · Emily R. McMullen, Nicholas A. Zoumberos, et al. · Archives of Pathology & Laboratory Medicine · 90
The CCN proteins: important signaling mediators in stem cell differentiation and tumorigenesis.
2010 · Guo-Wei Zuo, Christopher D Kohls, et al. · PubMed · 87
A reproducible scaffold-free 3D organoid model to study neoplastic progression in breast cancer
2018 · Sabra I. Djomehri, Boris Burman, et al. · Journal of Cell Communication and Signaling · 78
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CCN6 Modulates BMP Signaling via the Smad-Independent TAK1/p38 Pathway, Acting to Suppress Metastasis of Breast Cancer
2012 · Anupama Pal, Wei Huang, et al. · Cancer Research · 70
The CCN family acting throughout the body: recent research developments
2013 · Satoshi Kubota, Masaharu Takigawa · BioMolecular Concepts · 69
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CCN6 (WISP3) decreases ZEB1-mediated EMT and invasion by attenuation of IGF-1 receptor signaling in breast cancer
2011 · Guadalupe Lorenzatti, Wei Huang, et al. · Journal of Cell Science · 66
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Inhibition of CCN6 (WISP3) expression promotes neoplastic progression and enhances the effects of insulin-like growth factor-1 on breast epithelial cells
2005 · Yanhong Zhang, Quintin Pan, et al. · Breast Cancer Research · 65
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Inhibition of CCN6 (Wnt-1-Induced Signaling Protein 3) Down-Regulates E-Cadherin in the Breast Epithelium through Induction of Snail and ZEB1
2008 · Wei Huang, Yanhong Zhang, et al. · American Journal Of Pathology · 63
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Targeting CCN Proteins in Rheumatoid Arthritis and Osteoarthritis
2021 · Iona J. MacDonald, Chien-Chung Huang, et al. · International Journal of Molecular Sciences · 49
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Spatial-temporal modulation of CCN proteins during wound healing in human skin in vivo
2011 · Laure Rittié, Bernard Perbal, et al. · Journal of Cell Communication and Signaling · 47
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Proteins on the catwalk: modelling the structural domains of the CCN family of proteins
2009 · Kenneth P. Holbourn, Bernard Perbal, et al. · Journal of Cell Communication and Signaling · 45
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Alternative splicing of CCN mRNAs …. it has been upon us
2009 · Bernard Perbal · Journal of Cell Communication and Signaling · 40
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WISP-3 inhibition of miR-452 promotes VEGF-A expression in chondrosarcoma cells and induces endothelial progenitor cells angiogenesis
2017 · Chih-Yang Lin, Huey-En Tzeng, et al. · Oncotarget · 39
CCN6-mediated MMP-9 activation enhances metastatic potential of human chondrosarcoma
2018 · Huey-En Tzeng, Chih-Hsin Tang, et al. · Cell Death and Disease · 38
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CCN6 enhances ICAM‐1 expression and cell motility in human chondrosarcoma cells
2011 · Yi‐Chin Fong, Chih‐Yang Lin, et al. · Journal of Cellular Physiology · 37
Expression profles of human CCN genes in patients with osteoarthritis or rheumatoid arthritis
2015 · Masatoshi Komatsu, Yukio Nakamura, et al. · Journal of Orthopaedic Science · 35
CCN6 (WISP3) as a New Regulator of the Epithelial Phenotype in Breast Cancer
2007 · Celina G. Kleer, Yanhong Zhang, et al. · Cells Tissues Organs · 34
Expression of CCN family of genes in human skin in vivo and alterations by solar-simulated ultraviolet irradiation
2009 · Taihao Quan, Sharon Shin, et al. · Journal of Cell Communication and Signaling · 32
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Works count: 158
Citation count: 2,462
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