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CCR5
Description:
A chemokine receptor on immune cells that functions as a coreceptor for HIV entry and is studied in immunology and infectious disease.
Primary topic:
HIV Research and Treatment (29%)
Related topics:
HIV Research and Treatment (29%),
Chemokine receptors and signaling (19%)
OpenAlex ID:
keywords/ccr5
Mesenchymal stem cells within tumour stroma promote breast cancer metastasis
2007
·
Antoine E. Karnoub
, Ajeeta B. Dash
, et al.
·
Nature
·
3,205
HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5
1996
·
Tatjana Dragic
, Virginia Litwin
, et al.
·
Nature
·
3,174
Homozygous Defect in HIV-1 Coreceptor Accounts for Resistance of Some Multiply-Exposed Individuals to HIV-1 Infection
1996
·
Rong Liu
, William A Paxton
, et al.
·
Cell
·
3,099
PDF
Resistance to HIV-1 infection in Caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene
1996
·
Michel Samson
, Frédérick Libert
, et al.
·
Nature
·
2,886
The β-Chemokine Receptors CCR3 and CCR5 Facilitate Infection by Primary HIV-1 Isolates
1996
·
Hyeryun Choe
, Michael Farzan
, et al.
·
Cell
·
2,287
PDF
CHEMOKINE RECEPTORS AS HIV-1 CORECEPTORS: Roles in Viral Entry, Tropism, and Disease
1999
·
Edward A. Berger
, Philip M. Murphy
, et al.
·
Annual Review of Immunology
·
2,183
A TALE nuclease architecture for efficient genome editing
2010
·
Jeffrey C Miller
, Siyuan Tan
, et al.
·
Nature Biotechnology
·
2,097
Differential Expression of Chemokine Receptors and Chemotactic Responsiveness of Type 1 T Helper Cells (Th1s) and Th2s
1998
·
Raffaella Bonecchi
, Giancarlo Bianchi
, et al.
·
The Journal of Experimental Medicine
·
2,017
The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry
1996
·
Conrad C. Bleul
, Michael Farzan
, et al.
·
Nature
·
1,953
Long-Term Control of HIV by CCR5 Delta32/Delta32 Stem-Cell Transplantation
2009
·
Gero Hütter
, Daniel Nowak
, et al.
·
New England Journal of Medicine
·
1,838
PDF
International Union of Pharmacology. XXII. Nomenclature for Chemokine Receptors
2000
·
Philip M. Murphy
, Marco Baggiolini
, et al.
·
Pharmacological Reviews
·
1,817
Role of the T cell in the genesis of angiotensin II–induced hypertension and vascular dysfunction
2007
·
Tomasz J. Guzik
, Nyssa E. Hoch
, et al.
·
The Journal of Experimental Medicine
·
1,734
PDF
Flexible Programs of Chemokine Receptor Expression on Human Polarized T Helper 1 and 2 Lymphocytes
1998
·
Federica Sallusto
, Danielle Lenig
, et al.
·
The Journal of Experimental Medicine
·
1,543
PDF
The chemokine receptors CXCR3 and CCR5 mark subsets of T cells associated with certain inflammatory reactions.
1998
·
S Qin
, J B Rottman
, et al.
·
Journal of Clinical Investigation
·
1,359
Change in Coreceptor Use Correlates with Disease Progression in HIV-1–Infected Individuals
1997
·
Ruth I. Connor
, Kristine E. Sheridan
, et al.
·
The Journal of Experimental Medicine
·
1,354
PDF
Monocyte subsets differentially employ CCR2, CCR5, and CX3CR1 to accumulate within atherosclerotic plaques
2007
·
Frank Tacke
, David Alvarez
, et al.
·
Journal of Clinical Investigation
·
1,322
PDF
Effects of CCR5 and CD4 Cell Surface Concentrations on Infections by Macrophagetropic Isolates of Human Immunodeficiency Virus Type 1
1998
·
Emily J. Platt
, Kathy Wehrly
, et al.
·
Journal of Virology
·
1,221
PDF
Rapid and coordinated switch in chemokine receptor expression during dendritic cell maturation
1998
·
Federica Sallusto
, Patrick Schaerli
, et al.
·
European Journal of Immunology
·
1,183
CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5
1996
·
Lijun Wu
, Norma P. Gerard
, et al.
·
Nature
·
1,168
The HIV coreceptors CXCR4 and CCR5 are differentially expressed and regulated on human T lymphocytes
1997
·
Conrad C. Bleul
, Lijun Wu
, et al.
·
Proceedings of the National Academy of Sciences
·
1,135
The Influence of CCL3L1 Gene-Containing Segmental Duplications on HIV-1/AIDS Susceptibility
2005
·
Enrique Gonzalez
, Hemant Kulkarni
, et al.
·
Science
·
1,129
Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis
2017
·
Deepak A. Rao
, Michael F. Gurish
, et al.
·
Nature
·
1,119
COVID-19 severity correlates with airway epithelium–immune cell interactions identified by single-cell analysis
2020
·
Robert Lorenz Chua
, Soeren Lukassen
, et al.
·
Nature Biotechnology
·
1,035
PDF
CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5
1996
·
Alexandra Trkola
, Tatjana Dragic
, et al.
·
Nature
·
1,034
Shorter Survival in Advanced Human Immunodeficiency Virus Type 1 Infection Is More Closely Associated with T Lymphocyte Activation than with Plasma Virus Burden or Virus Chemokine Coreceptor Usage
1999
·
Janis V. Giorgi
, Lance E. Hultin
, et al.
·
The Journal of Infectious Diseases
·
1,033
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Works count:
11,420
Citation count:
417,000
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