Keyword

CD47

Description: CD47 is a cell-surface protein involved in immune regulation, including signaling that can inhibit macrophage engulfment of cells.

Primary topic: Phagocytosis and Immune Regulation (36%)

OpenAlex ID: keywords/cd47

Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer

2017 · Sushrut Kamerkar, Valerie S. LeBleu, et al. · Nature · 2,624

Role of CD47 as a Marker of Self on Red Blood Cells

2000 · Per-Arne Oldenborg, Alex Zheleznyak, et al. · Science · 1,972

CD47 Is an Adverse Prognostic Factor and Therapeutic Antibody Target on Human Acute Myeloid Leukemia Stem Cells

2009 · Ravindra Majeti, Mark P. Chao, et al. · Cell · 1,749

The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors

2012 · Stephen B. Willingham, Jens-Peter Volkmer, et al. · Proceedings of the National Academy of Sciences · 1,667

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CD47 Is Upregulated on Circulating Hematopoietic Stem Cells and Leukemia Cells to Avoid Phagocytosis

2009 · Siddhartha Jaiswal, Catriona H.M. Jamieson, et al. · Cell · 1,583

Cell-Surface Calreticulin Initiates Clearance of Viable or Apoptotic Cells through trans-Activation of LRP on the Phagocyte

2005 · Shyra J. Gardai, Kathleen A. McPhillips, et al. · Cell · 1,473

MYC regulates the antitumor immune response through CD47 and PD-L1

2016 · Stephanie C. Casey, Ling Tong, et al. · Science · 1,397

In vivo CRISPR screening identifies Ptpn2 as a cancer immunotherapy target

2017 · Robert T. Manguso, Hans W. Pope, et al. · Nature · 1,140

Identification of a population of blood circulating tumor cells from breast cancer patients that initiates metastasis in a xenograft assay

2013 · Irène Baccelli, Andreas Schneeweiss, et al. · Nature Biotechnology · 1,048

Minimal "Self" Peptides That Inhibit Phagocytic Clearance and Enhance Delivery of Nanoparticles

2013 · Pia L. Rodriguez, Takamasa Harada, et al. · Science · 986

Integrin-associated protein (CD47) and its ligands

2001 · E Brown · Trends in Cell Biology · 878

The Interaction Between Signal Regulatory Protein Alpha (SIRPα) and CD47: Structure, Function, and Therapeutic Target

2013 · A. Neil Barclay, Timo K. van den Berg · Annual Review of Immunology · 838

Calreticulin Is the Dominant Pro-Phagocytic Signal on Multiple Human Cancers and Is Counterbalanced by CD47

2010 · Mark P. Chao, Siddhartha Jaiswal, et al. · Science Translational Medicine · 774

The CD47-SIRPα Immune Checkpoint

2020 · Meike E.W. Logtenberg, Ferenc A. Scheeren, et al. · Immunity · 740

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CD47-blocking antibodies restore phagocytosis and prevent atherosclerosis

2016 · Yoko Kojima, Jens-Peter Volkmer, et al. · Nature · 680

Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cells

2009 · Keith Syson Chan, Inigo Espinosa, et al. · Proceedings of the National Academy of Sciences · 661

The CD47–SIRPα pathway in cancer immune evasion and potential therapeutic implications

2012 · Mark P Chao, Irving L Weissman, et al. · Current Opinion in Immunology · 650

Decreased Resistance to Bacterial Infection and Granulocyte Defects in IAP-Deficient Mice

1996 · Frederik P. Lindberg, Daniel C. Bullard, et al. · Science · 607

First-in-Human, First-in-Class Phase I Trial of the Anti-CD47 Antibody Hu5F9-G4 in Patients With Advanced Cancers

2019 · Branimir I. Sikic, Nehal Lakhani, et al. · Journal of Clinical Oncology · 600

MicroRNA profiling of multiple sclerosis lesions identifies modulators of the regulatory protein CD47

2009 · Andreas Junker, Markus Krumbholz, et al. · Brain · 595

The CD47‐SIRPα signaling axis as an innate immune checkpoint in cancer

2017 · Hanke L. Matlung, Katka Szilagyi, et al. · Immunological Reviews · 561

Engagement of MHC class I by the inhibitory receptor LILRB1 suppresses macrophages and is a target of cancer immunotherapy

2017 · Amira A. Barkal, Kipp Weiskopf, et al. · Nature Immunology · 558

Molecular Basis for the Regulation of Angiogenesis by Thrombospondin-1 and -2

2012 · P. R. Lawler, J. Lawler · Cold Spring Harbor Perspectives in Medicine · 531

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A cell surface receptor complex for fibrillar beta-amyloid mediates microglial activation.

2003 · Maria E Bamberger, Meera E Harris, et al. · PubMed · 525

Factors that Control the Circulation Time of Nanoparticles in Blood: Challenges, Solutions and Future Prospects

2010 · Jin-Wook Yoo, Elizabeth Chambers, et al. · Current Pharmaceutical Design · 521

Works count: 5,478

Citation count: 147,100