Keyword

cell contractility

Description: The capacity of cells to generate contractile forces that alter their shape, move them, or remodel surrounding tissues.

Primary topic: Cellular Mechanics and Interactions (58%)

OpenAlex ID: keywords/cell-contractility

Tissue Cells Feel and Respond to the Stiffness of Their Substrate

2005 · Dennis E. Discher, Paul Janmey, et al. · Science · 6,381

Cells lying on a bed of microneedles: An approach to isolate mechanical force

2003 · John L. Tan, Joe Tien, et al. · Proceedings of the National Academy of Sciences · 1,967

Focal Adhesions, Contractility, and Signaling

1996 · Keith Burridge, Magdalena Chrzanowska-Wodnicka · Annual Review of Cell and Developmental Biology · 1,944

Rho-stimulated contractility drives the formation of stress fibers and focal adhesions.

1996 · M Chrzanowska-Wodnicka, K Burridge · The Journal of Cell Biology · 1,683

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Focal Contacts as Mechanosensors

2001 · Daniel Riveline, Eli Zamir, et al. · The Journal of Cell Biology · 1,420

Cell–matrix adhesion

2007 · Allison L. Berrier, Kenneth M. Yamada · Journal of Cellular Physiology · 969

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Assembly of Fibronectin Extracellular Matrix

2010 · Purva Singh, Cara Carraher, et al. · Annual Review of Cell and Developmental Biology · 964

Confinement and Low Adhesion Induce Fast Amoeboid Migration of Slow Mesenchymal Cells

2015 · Yan-Jun Liu, Maël Le Berre, et al. · Cell · 864

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Emergent patterns of growth controlled by multicellular form and mechanics

2005 · Celeste M. Nelson, Ronald P. Jean, et al. · Proceedings of the National Academy of Sciences · 854

The nucleus acts as a ruler tailoring cell responses to spatial constraints

2020 · A. J. Lomakin, C. J. Cattin, et al. · Science · 610

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Rho-mediated Contractility Exposes a Cryptic Site in Fibronectin and Induces Fibronectin Matrix Assembly

1998 · Cuiling Zhong, Magdalena Chrzanowska-Wodnicka, et al. · The Journal of Cell Biology · 605

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Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation

2011 · Jean-Cheng Kuo, Xuemei Han, et al. · Nature Cell Biology · 591

Connective tissue morphogenesis by fibroblast traction

1982 · David Stopak, Albert K. Harris · Developmental Biology · 586

Independent regulation of tumor cell migration by matrix stiffness and confinement

2012 · Amit Pathak, Sanjay Kumar · Proceedings of the National Academy of Sciences · 568

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Fibroblast polarization is a matrix-rigidity-dependent process controlled by focal adhesion mechanosensing

2011 · Masha Prager-Khoutorsky, Alexandra Lichtenstein, et al. · Nature Cell Biology · 564

E-cadherin junctions as active mechanical integrators in tissue dynamics

2015 · Thomas Lecuit, Alpha S. Yap · Nature Cell Biology · 548

Vimentin contributes to epithelial-mesenchymal transition cancer cell mechanics by mediating cytoskeletal organization and focal adhesion maturation

2015 · Ching-Yi Liu, Hsi-Hui Lin, et al. · Oncotarget · 536

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Myosin IIA regulates cell motility and actomyosin–microtubule crosstalk

2007 · Sharona Even-Ram, Andrew D. Doyle, et al. · Nature Cell Biology · 508

Mechanical signaling through the cytoskeleton regulates cell proliferation by coordinated focal adhesion and Rho GTPase signaling

2011 · Paolo P. Provenzano, Patricia J. Keely · Journal of Cell Science · 494

Contact Guidance Mediated Three-Dimensional Cell Migration is Regulated by Rho/ROCK-Dependent Matrix Reorganization

2008 · Paolo P. Provenzano, David R. Inman, et al. · Biophysical Journal · 493

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Directed cell invasion and migration during metastasis

2011 · Jose Javier Bravo-Cordero, Louis Hodgson, et al. · Current Opinion in Cell Biology · 462

Hemostatic, inflammatory, and fibroblast responses are blunted in mice lacking gelsolin

1995 · Walter Witke, Arlene H Sharpe, et al. · Cell · 431

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Cell tension, matrix mechanics, and cancer development

2005 · Sui Huang, Donald E. Ingber · Cancer Cell · 429

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Feeling Stress: The Mechanics of Cancer Progression and Aggression

2018 · Josette M. Northcott, Ivory S. Dean, et al. · Frontiers in Cell and Developmental Biology · 414

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Coaction of intercellular adhesion and cortical tension specifies tissue surface tension

2010 · M. Lisa Manning, Ramsey A. Foty, et al. · Proceedings of the National Academy of Sciences · 410

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Works count: 2,719

Citation count: 92,220