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cellular aging
Description:
The progressive decline in cellular function and capacity for survival associated with aging and biological senescence.
Primary topic:
Telomeres, Telomerase, and Senescence (25%)
Related topics:
Telomeres, Telomerase, and Senescence (25%),
Genetics, Aging, and Longevity in Model Organisms (13%)
OpenAlex ID:
keywords/cellular-aging
A biomarker that identifies senescent human cells in culture and in aging skin in vivo.
1995
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G P Dimri
, X Lee
, et al.
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Proceedings of the National Academy of Sciences
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7,473
Telomeres shorten during ageing of human fibroblasts
1990
·
Calvin B. Harley
, A. Bruce Futcher
, et al.
·
Nature
·
5,750
Evidence for Cardiomyocyte Renewal in Humans
2009
·
Olaf Bergmann
, Ratan D. Bhardwaj
, et al.
·
Science
·
3,130
Accelerated telomere shortening in response to life stress
2004
·
Elissa S. Epel
, Elizabeth H. Blackburn
, et al.
·
Proceedings of the National Academy of Sciences
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3,001
hSIR2SIRT1 Functions as an NAD-Dependent p53 Deacetylase
2001
·
Homayoun Vaziri
, Scott K. Dessain
, et al.
·
Cell
·
2,661
PDF
A theory of marginotomy
1973
·
A.M. Olovnikov
·
Journal of Theoretical Biology
·
1,847
Human DNA Repair Genes
2001
·
Richard D. Wood
, Michael Mitchell
, et al.
·
Science
·
1,488
Senescence‐associated β‐galactosidase is lysosomal β‐galactosidase
2006
·
Bo Yun Lee
, Jung A. Han
, et al.
·
Aging Cell
·
1,441
PDF
Telomerase activity in human germline and embryonic tissues and cells
1996
·
Woodring E. Wright
, Mieczyslaw A. Piatyszek
, et al.
·
Developmental Genetics
·
1,406
Telomere states and cell fates
2000
·
Elizabeth H. Blackburn
·
Nature
·
1,380
Extended Kalman filtering for battery management systems of LiPB-based HEV battery packs
2004
·
Gregory L. Plett
·
Journal of Power Sources
·
1,351
Age-related changes in oxidized proteins.
1987
·
C.N. Oliver
, B.W. Ahn
, et al.
·
Journal of Biological Chemistry
·
1,306
Achieving the Balance between ROS and Antioxidants: When to Use the Synthetic Antioxidants
2013
·
Borut Poljsak
, Dušan Šuput
, et al.
·
Oxidative Medicine and Cellular Longevity
·
1,300
PDF
Telomere end-replication problem and cell aging
1992
·
Michael Z. Levy
, Richard C. Allsopp
, et al.
·
Journal of Molecular Biology
·
1,068
Replicative life-span of cultivated human cells. Effects of donor's age, tissue, and genotype.
1970
·
G M Martin
, C A Sprague
, et al.
·
PubMed
·
1,003
Ageing and infection
2002
·
Gaëtan Gavazzi
, Karl-Heinz Krause
·
The Lancet Infectious Diseases
·
988
In Vivo Amelioration of Age-Associated Hallmarks by Partial Reprogramming
2016
·
Alejandro Ocampo
, Pradeep Reddy
, et al.
·
Cell
·
986
PDF
The telomere syndromes
2012
·
Mary Armanios
, Elizabeth H. Blackburn
·
Nature Reviews Genetics
·
983
Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT
1997
·
Scott L. Weinrich
, Ron Pruzan
, et al.
·
Nature Genetics
·
963
Mitochondrial role in cell aging
1980
·
J. Miquel
, A.C. Economos
, et al.
·
Experimental Gerontology
·
937
Human Telomerase and Its Regulation
2002
·
Yu-Sheng Cong
, Woodring E. Wright
, et al.
·
Microbiology and Molecular Biology Reviews
·
899
Autophagy maintains the metabolism and function of young and old stem cells
2017
·
Theodore T. Ho
, Matthew R. Warr
, et al.
·
Nature
·
895
Social Determinants of Cardiovascular Disease
2022
·
Tiffany M. Powell-Wiley
, Yvonne Baumer
, et al.
·
Circulation Research
·
880
PDF
Epigenetic clock for skin and blood cells applied to Hutchinson Gilford Progeria Syndrome and ex vivo studies
2018
·
Steve Horvath
, Junko Oshima
, et al.
·
Aging
·
810
Atomic force microscopy probing of cell elasticity
2007
·
Tatyana G. Kuznetsova
, Maria N. Starodubtseva
, et al.
·
Micron
·
796
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Works count:
9,282
Citation count:
237,700
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