Keyword

ceramide

Description: A family of sphingolipid molecules that serve as structural components of cell membranes and signaling molecules in cellular processes.

Primary topic: Sphingolipid Metabolism and Signaling (34%)

Wikidata ID: wiki/Q424213

OpenAlex ID: keywords/ceramide

Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes

2008 · Katarina Trajkovic, Chieh Hsu, et al. · Science · 3,631

Principles of bioactive lipid signalling: lessons from sphingolipids

2008 · Yusuf A. Hannun, Lina M. Obeid · Nature Reviews Molecular Cell Biology · 3,341

Mechanisms of Insulin Action and Insulin Resistance

2018 · Max C. Petersen, Gerald I. Shulman · Physiological Reviews · 3,008

The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance

2011 · Bolormaa Vandanmagsar, Yun-Hee Youm, et al. · Nature Medicine · 2,648

Therapy of CF-Patients with Amitriptyline and Placebo - a Randomised, Double-Blind, Placebo-Controlled Phase IIb Multicenter, Cohort-Study

2013 · Lutz Nährlich, Jochen G. Mainz, et al. · Cellular Physiology and Biochemistry · 2,525

Mechanisms for Insulin Resistance: Common Threads and Missing Links

2012 · Varman T. Samuel, Gerald I. Shulman · Cell · 2,289

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The skin: an indispensable barrier

2008 · Ehrhardt Proksch, Johanna M. Brandner, et al. · Experimental Dermatology · 2,047

Oxygen free radicals and iron in relation to biology and medicine: Some problems and concepts

1986 · Barry Halliwell, John M.C. Gutteridge · Archives of Biochemistry and Biophysics · 2,038

Secretory Mechanisms and Intercellular Transfer of MicroRNAs in Living Cells

2010 · Nobuyoshi Kosaka, Haruhisa Iguchi, et al. · Journal of Biological Chemistry · 1,950

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Programmed Cell Death Induced by Ceramide

1993 · Lina M. Obeid, Corinne M. Linardic, et al. · Science · 1,793

Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis

1996 · Marcel Verheij, Ron Bose, et al. · Nature · 1,767

Functions of Ceramide in Coordinating Cellular Responses to Stress

1996 · Yusuf A. Hannun · Science · 1,617

Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death.

1995 · N Zamzami, P Marchetti, et al. · The Journal of Experimental Medicine · 1,567

Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate

1996 · Olivier Cuvillier, Grisha Pirianov, et al. · Nature · 1,530

Thematic review series: The Pathogenesis of Atherosclerosis. Effects of infection and inflammation on lipid and lipoprotein metabolism mechanisms and consequences to the host

2004 · Weerapan Khovidhunkit, Min-Sun Kim, et al. · Journal of Lipid Research · 1,481

Lipid-Induced Insulin Resistance in Human Muscle Is Associated With Changes in Diacylglycerol, Protein Kinase C, and IκB-α

2002 · Samar I. Itani, Neil B. Ruderman, et al. · Diabetes · 1,390

BAX and BAK Regulation of Endoplasmic Reticulum Ca 2+ : A Control Point for Apoptosis

2003 · Luca Scorrano, Scott A. Oakes, et al. · Science · 1,386

Sphingolipid metabolites in inflammatory disease

2014 · Michael Maceyka, Sarah Spiegel · Nature · 1,277

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Lipotoxic heart disease in obese rats: Implications for human obesity

2000 · Yan-Ting Zhou, Paul Grayburn, et al. · Proceedings of the National Academy of Sciences · 1,264

The sphingomyelin cycle and the second messenger function of ceramide.

1994 · Y.A. Hannun · Journal of Biological Chemistry · 1,235

Biologically active sphingolipids in cancer pathogenesis and treatment

2004 · Besim Ogretmen, Yusuf A. Hannun · Nature reviews. Cancer · 1,215

Sphingolipid metabolism in cancer signalling and therapy

2017 · Besim Ogretmen · Nature reviews. Cancer · 1,202

Fatty acid-induced β cell apoptosis: A link between obesity and diabetes

1998 · Michio Shimabukuro, Yan-Ting Zhou, et al. · Proceedings of the National Academy of Sciences · 1,142

An Overview of Sphingolipid Metabolism: From Synthesis to Breakdown

2010 · Christopher R. Gault, Lina M. Obeid, et al. · Advances in experimental medicine and biology · 1,076

TNF activates NF-κB by phosphatidylcholine-specific phospholipase C-induced “Acidic” sphingomyelin breakdown

1992 · Stefan Schütze, Karin Potthoff, et al. · Cell · 1,046

Works count: 19,280

Citation count: 690,800