Keyword

combinatorial libraries

Description: Collections of systematically varied molecules or biological sequences assembled for screening and analysis in fields such as chemistry and bioinformatics.

Primary topic: Chemical Synthesis and Analysis (29%)

OpenAlex ID: keywords/combinatorial-libraries

Click Chemistry: Diverse Chemical Function from a Few Good Reactions

2001 · Hartmuth C. Kolb, M. G. Finn, et al. · Angewandte Chemie International Edition · 13,765

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A Knowledge-Based Approach in Designing Combinatorial or Medicinal Chemistry Libraries for Drug Discovery. 1. A Qualitative and Quantitative Characterization of Known Drug Databases

1998 · Arup K. Ghose, Vellarkad N. Viswanadhan, et al. · Journal of Combinatorial Chemistry · 3,073

Click-Chemie: diverse chemische Funktionalität mit einer Handvoll guter Reaktionen

2001 · Hartmuth C. Kolb, M. G. Finn, et al. · Angewandte Chemie · 1,624

Recent advances in dynamic covalent chemistry

2013 · Yinghua Jin, Chao Yu, et al. · Chemical Society Reviews · 1,487

Selection of peptides with semiconductor binding specificity for directed nanocrystal assembly

2000 · Sandra R. Whaley, D. S. English, et al. · Nature · 1,291

A combinatorial library of lipid-like materials for delivery of RNAi therapeutics

2008 · Akin Akinc, Andreas Zumbuehl, et al. · Nature Biotechnology · 1,228

Phage-encoded combinatorial chemical libraries based on bicyclic peptides

2009 · Christian Heinis, Trevor Rutherford, et al. · Nature Chemical Biology · 743

Natural Product-like Combinatorial Libraries Based on Privileged Structures. 1. General Principles and Solid-Phase Synthesis of Benzopyrans

2000 · K. C. Nicolaou, J. A. Pfefferkorn, et al. · Journal of the American Chemical Society · 678

Advances in Drug Research

1964 · Bernard, Meyer Testa, et al. · Academic Press eBooks · 609

Diversity-oriented synthesis: exploring the intersections between chemistry and biology

2005 · Derek S Tan · Nature Chemical Biology · 605

Designing Repeat Proteins: Well-expressed, Soluble and Stable Proteins from Combinatorial Libraries of Consensus Ankyrin Repeat Proteins

2003 · H.Kaspar Binz, Michael T Stumpp, et al. · Journal of Molecular Biology · 589

The Current Status of Heterocyclic Combinatorial Libraries

1997 · Adel Nefzi, John M. Ostresh, et al. · Chemical Reviews · 586

Combinatorial hydrogel library enables identification of materials that mitigate the foreign body response in primates

2016 · Arturo J Vegas, Omid Veiseh, et al. · Nature Biotechnology · 551

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Drug Design Strategies for Targeting G-Protein-Coupled Receptors

2002 · Thomas Klabunde, Gerhard Hessler · ChemBioChem · 500

Molecular Shape Diversity of Combinatorial Libraries: A Prerequisite for Broad Bioactivity

2003 · Wolfgang H. B. Sauer, Matthias K. Schwarz · Journal of Chemical Information and Computer Sciences · 498

In situ click chemistry: probing the binding landscapes of biological molecules

2010 · Sreeman K. Mamidyala, M. G. Finn · Chemical Society Reviews · 489

Protein Purification

2011 · Methods of biochemical analysis · 482

Multicomponent Reactions Are Accelerated in Water

2003 · Michael C. Pirrung, Koushik Das Sarma · Journal of the American Chemical Society · 437

Ionic-Liquid-Supported Synthesis: A Novel Liquid-Phase Strategy for Organic Synthesis

2006 · Weishi Miao, Tak Hang Chan · Accounts of Chemical Research · 433

Computational Methods in Developing Quantitative Structure-Activity Relationships (QSAR): A Review

2006 · Arkadiusz Dudek, Tomasz Arodz, et al. · Combinatorial Chemistry & High Throughput Screening · 429

From Molecular Diversity to Catalysis: Lessons from the Immune System

1995 · Peter G. Schultz, Richard A. Lerner · Science · 420

Selection criteria for drug‐like compounds

2003 · Ingo Muegge · Medicinal Research Reviews · 415

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Small-molecule antagonists of apoptosis suppressor XIAP exhibit broad antitumor activity

2004 · Aaron D. Schimmer, Kate Welsh, et al. · Cancer Cell · 412

Stimulating Concepts in Chemistry

2000 · Wiley eBooks · 412

Synthesis of epothilones A and B in solid and solution phase

1997 · K. C. Nicolaou, N. Winssinger, et al. · Nature · 401

Works count: 3,195

Citation count: 107,700