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Keyword

cyclin E

Description: A cell-cycle regulatory protein that promotes progression from the G1 phase into DNA synthesis in eukaryotic cells.
Wikidata ID: wiki/Q24724860
OpenAlex ID: keywords/cyclin-e
CDK inhibitors: positive and negative regulators of G1-phase progression
1999 · C. J. Sherr, J. M. Roberts · Genes & Development · 6,119
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The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
1993 · J Wade Harper · Cell · 5,652
American Society of Clinical Oncology 2007 Update of Recommendations for the Use of Tumor Markers in Breast Cancer
2007 · Lyndsay Harris, Herbert Fritsche, et al. · Journal of Clinical Oncology · 2,217
WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis.
1994 · W S el-Deiry, J W Harper, et al. · PubMed · 2,029
p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest
1994 · Vjekoslav Dulić, William K. Kaufmann, et al. · Cell · 1,466
The Pezcoller lecture: cancer cell cycles revisited.
2000 · C J Sherr · PubMed · 1,196
Human Cyclin E, a Nuclear Protein Essential for the G1-to-S Phase Transition
1995 · Motoaki Ohtsubo, Anne M. Theodoras, et al. · Molecular and Cellular Biology · 1,148
hippo Encodes a Ste-20 Family Protein Kinase that Restricts Cell Proliferation and Promotes Apoptosis in Conjunction with salvador and warts
2003 · Shian Wu, Jianbin Huang, et al. · Cell · 1,098
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Living with or without cyclins and cyclin-dependent kinases
2004 · Charles J. Sherr, James M. Roberts · Genes & Development · 1,089
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FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation
2007 · Markus Welcker, Bruce E. Clurman · Nature reviews. Cancer · 1,083
Cdk Phosphorylation Triggers Sequential Intramolecular Interactions that Progressively Block Rb Functions as Cells Move through G1
1999 · J.William Harbour, Robin X Luo, et al. · Cell · 1,055
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Recycling the Cell Cycle
2004 · Andrew W Murray · Cell · 1,053
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Formation and Activation of a Cyclin E-cdk2 Complex During the G 1 Phase of the Human Cell Cycle
1992 · Andrew Koff, Antonio Giordano, et al. · Science · 1,043
Regulation of retinoblastoma protein functions by ectopic expression of human cyclins
1992 · Philip W. Hinds, Sibylle Mittnacht, et al. · Cell · 995
The Drosophila Mst Ortholog, hippo, Restricts Growth and Cell Proliferation and Promotes Apoptosis
2003 · Kieran F. Harvey, Cathie M. Pfleger, et al. · Cell · 976
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Acceleration of the G 1 /S Phase Transition by Expression of Cyclins Dl and E with an Inducible System
1994 · Dalia Resnitzky, Manfred Gossen, et al. · Molecular and Cellular Biology · 965
The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation
2004 · Markus Welcker, Amir Orian, et al. · Proceedings of the National Academy of Sciences · 941
Cellular Targets for Activation by the E2F1 Transcription Factor Include DNA Synthesis- and G 1 /S-Regulatory Genes
1995 · James DeGregori, Timothy Kowalik, et al. · Molecular and Cellular Biology · 920
Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients
1997 · Peggy L. Porter, Kathleen E. Malone, et al. · Nature Medicine · 901
Association of human cyclin E with a periodic G1-S phase protein kinase
1992 · V Dulic, E Lees, et al. · Science · 881
salvador Promotes Both Cell Cycle Exit and Apoptosis in Drosophila and Is Mutated in Human Cancer Cell Lines
2002 · Nicolas Tapon, Kieran F. Harvey, et al. · Cell · 856
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Nucleotide Deficiency Promotes Genomic Instability in Early Stages of Cancer Development
2011 · Assaf C. Bester, Maayan Roniger, et al. · Cell · 854
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Isolation of three novel human cyclins by rescue of G1 cyclin (cln) function in yeast
1991 · Daniel J. Lew, Vjekoslav Dulić, et al. · Cell · 833
Coordination of Growth and Cell Division in the Drosophila Wing
1998 · Thomas P Neufeld, Aida Flor A de la Cruz, et al. · Cell · 769
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Phosphorylation-Dependent Ubiquitination of Cyclin E by the SCF Fbw7 Ubiquitin Ligase
2001 · Deanna M. Koepp, Laura K. Schaefer, et al. · Science · 762
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Works count: 7,059
Citation count: 276,700
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