Keyword

cyclins

Description: Cyclins are regulatory proteins that control progression through the cell cycle and are studied in cell biology and cancer research.

Primary topic: Cancer-related Molecular Pathways (25%)

Wikidata ID: wiki/Q59250999

OpenAlex ID: keywords/cyclins

Universal control mechanism regulating onset of M-phase

1990 · Paul Nurse · Nature · 2,831

G1 phase progression: Cycling on cue

1994 · Charles J. Sherr · Cell · 2,674

Cyclins and cancer II: Cyclin D and CDK inhibitors come of age

1994 · Tony Hunter, Jonathan Pines · Cell · 2,091

Mammalian G1 cyclins

1993 · Charles J. Sherr · Cell · 1,960

Molecular evidence for an ancient duplication of the entire yeast genome

1997 · Kenneth H. Wolfe, Denis C. Shields · Nature · 1,785

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The cell cycle: a review of regulation, deregulation and therapeutic targets in cancer

2003 · Katrien Vermeulen, Dirk R. Van Bockstaele, et al. · Cell Proliferation · 1,774

Cyclin/PCNA is the auxiliary protein of DNA polymerase-δ

1987 · Rodrigo Bravo, Rainer Frank, et al. · Nature · 1,740

Cyclin-dependent kinases

2014 · Marcos Malumbres · Genome biology · 1,662

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Cyclin: A protein specified by maternal mRNA in sea urchin eggs that is destroyed at each cleavage division

1983 · Tom Evans, Eric T. Rosenthal, et al. · Cell · 1,516

The Proteasome: Paradigm of a Self-Compartmentalizing Protease

1998 · Wolfgang Baumeister, Jochen Walz, et al. · Cell · 1,495

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Cdks, cyclins and CKIs: roles beyond cell cycle regulation

2013 · Shuhui Lim, Philipp Kaldis · Development · 1,487

Ubiquitin ligases: cell-cycle control and cancer

2006 · Keiichi I. Nakayama, Keiichi I. Nakayama, et al. · Nature reviews. Cancer · 1,437

A novel cyclin encoded by a bcl1-linked candidate oncogene

1991 · Toru Motokura, Theodora Bloom, et al. · Nature · 1,265

The proteasome: a suitable antineoplastic target

2004 · Julian Adams · Nature reviews. Cancer · 1,202

Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: a target for cancer chemotherapy

2003 · F Chang, J T Lee, et al. · Leukemia · 1,180

Colony-stimulating factor 1 regulates novel cyclins during the G1 phase of the cell cycle

1991 · Hitoshl Matsushime, Martine F. Roussel, et al. · Cell · 1,167

Cell cycle control in mammalian cells: role of cyclins, cyclin dependent kinases (CDKs), growth suppressor genes and cyclin-dependent kinase inhibitors (CKIs).

1995 · X Graña, E P Reddy · PubMed · 1,123

The role of cyclin synthesis and degradation in the control of maturation promoting factor activity

1989 · Andrew W. Murray, Mark J. Solomon, et al. · Nature · 1,096

Living with or without cyclins and cyclin-dependent kinases

2004 · Charles J. Sherr, James M. Roberts · Genes & Development · 1,089

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Functional identity of proliferating cell nuclear antigen and a DNA polymerase-δ auxiliary protein

1987 · Gregory Prelich, Cheng-Keat Tan, et al. · Nature · 1,059

Recycling the Cell Cycle

2004 · Andrew W Murray · Cell · 1,053

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Chapter 30 Cell Cycle Extracts

1991 · Andrew W. Murray · Methods in cell biology · 953

A family of human cdc2‐related protein kinases.

1992 · M. Meyerson, G.H. Enders, et al. · The EMBO Journal · 923

Existence of two populations of cyclin/proliferating cell nuclear antigen during the cell cycle: association with DNA replication sites.

1987 · R Bravo, H Macdonald-Bravo · The Journal of Cell Biology · 917

The Anaphase-Promoting Complex

2002 · Jan-Michael Peters · Molecular Cell · 909

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Works count: 4,424

Citation count: 191,400