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dat-1
Description:
The gene encoding the dopamine transporter in the nematode Caenorhabditis elegans, which regulates dopamine signaling by reuptake.
Primary topic:
Genetics, Aging, and Longevity in Model Organisms (53%)
Related topics:
Genetics, Aging, and Longevity in Model Organisms (53%),
Neurobiology and Insect Physiology Research (33%)
OpenAlex ID:
keywords/dat-1
Dopamine transporters depolarize neurons by a channel mechanism
2004
·
Lucia Carvelli
, Paul W. McDonald
, et al.
·
Proceedings of the National Academy of Sciences
·
142
PDF
Chronic exposure to UV-aged microplastics induces neurotoxicity by affecting dopamine, glutamate, and serotonin neurotransmission in Caenorhabditis elegans
2021
·
Haibo Chen
, Xin Hua
, et al.
·
Journal of Hazardous Materials
·
129
Dopamine transporter/syntaxin 1A interactions regulate transporter channel activity and dopaminergic synaptic transmission
2008
·
Lucia Carvelli
, Randy D. Blakely
, et al.
·
Proceedings of the National Academy of Sciences
·
92
Transmissions of serotonin, dopamine, and glutamate are required for the formation of neurotoxicity from Al2O3-NPs in nematodeCaenorhabditis elegans
2012
·
Yinxia Li
, Shunhui Yu
, et al.
·
Nanotoxicology
·
84
A genetic screen inCaenorhabditis elegansfor dopamine neuron insensitivity to 6‐hydroxydopamine identifies dopamine transporter mutants impacting transporter biosynthesis and trafficking
2005
·
Richard Nass
, Maureen K. Hahn
, et al.
·
Journal of Neurochemistry
·
83
Coumarin-derived Fe 3+ -selective fluorescent turn-off chemosensors: synthesis, properties, and applications in living cells
2013
·
Da En
, Yuan Guo
, et al.
·
RSC Advances
·
80
Acrylamide induces locomotor defects and degeneration of dopamine neurons in Caenorhabditis elegans
2015
·
Jia Li
, Dan Li
, et al.
·
Journal of Applied Toxicology
·
70
Lead (Pb) exposure induces dopaminergic neurotoxicity in Caenorhabditis elegans: Involvement of the dopamine transporter
2019
·
Ayodele Jacob Akinyemi
, Mahfuzur R. Miah
, et al.
·
Toxicology Reports
·
69
PDF
Toxicity interactions between manganese (Mn) and lead (Pb) or cadmium (Cd) in a model organism the nematode C. elegans
2018
·
Cailing Lu
, Kurt R. Svoboda
, et al.
·
Environmental Science and Pollution Research
·
60
Forward Genetic Analysis to Identify Determinants of Dopamine Signaling inCaenorhabditis elegansUsing Swimming-Induced Paralysis
2012
·
J Andrew Hardaway
, Shannon L Hardie
, et al.
·
G3 Genes Genomes Genetics
·
40
PDF
A role for dopamine in C. elegans avoidance behavior induced by mitochondrial stress
2022
·
Shih-Hua Chou
, Yen-Ju Chen
, et al.
·
Neuroscience Research
·
35
PDF
Photoaged Nanopolystyrene Affects Neurotransmission to Induce Transgenerational Neurotoxicity in Caenorhabditis elegans
2024
·
Haibo Chen
, Yulun Gu
, et al.
·
Environmental Science & Technology
·
29
Gene Expression Changes of Caenorhabditis elegans Larvae during Molting and Sleep-Like Lethargus
2014
·
Michal Turek
, Henrik Bringmann
·
PLoS ONE
·
29
PDF
The dopamine membrane transporter plays an active modulatory role in synaptic dopamine homeostasis
2021
·
Rosaria Formisano
, Katarzyna D. Rosikon
, et al.
·
Journal of Neuroscience Research
·
28
Synaptic vesicle fusion is modulated through feedback inhibition by dopamine auto‐receptors
2019
·
Rosaria Formisano
, Mahlet D. Mersha
, et al.
·
Synapse
·
23
Blockade and reversal of swimming-induced paralysis in C. elegans by the antipsychotic and D2-type dopamine receptor antagonist azaperone
2018
·
Osama Refai
, Randy D. Blakely
·
Neurochemistry International
·
23
Extracellular dopamine and alterations on dopamine transporter are related to reserpine toxicity in Caenorhabditis elegans
2015
·
Patrícia Reckziegel
, Pan Chen
, et al.
·
Archives of Toxicology
·
23
Neurotoxicity induced by aged microplastics from plastic bowls: Abnormal neurotransmission in Caenorhabditis elegans
2024
·
Liangzhong Li
, Ruixue Ma
, et al.
·
The Science of The Total Environment
·
22
Quantifying Levels of Dopaminergic Neuron Morphological Alteration and Degeneration in Caenorhabditis elegans
2021
·
Shefali R. Bijwadia
, Katherine Morton
, et al.
·
Journal of Visualized Experiments
·
19
Dopaminergic modulation by quercetin: In silico and in vivo evidence using Caenorhabditis elegans as a model
2023
·
Willian Goulart Salgueiro
, Marcell Valandro Soares
, et al.
·
Chemico-Biological Interactions
·
18
Latent alterations in swimming behavior by developmental methylmercury exposure are modulated by the homolog of tyrosine hydroxylase in Caenorhabditis elegans
2021
·
Tao Ke
, Lisa M. Prince
, et al.
·
Neurotoxicology and Teratology
·
18
β-Phenylethylamine requires the dopamine transporter to increase extracellular dopamine in Caenorhabditis elegans dopaminergic neurons
2013
·
Murad Hossain
, Rochelle N. Wickramasekara
, et al.
·
Neurochemistry International
·
18
Sequence determinants of the Caenhorhabditis elegans dopamine transporter dictating in vivo axonal export and synaptic localization
2016
·
Sarah B. Robinson
, J. Andrew Hardaway
, et al.
·
Molecular and Cellular Neuroscience
·
17
6:2 Chlorinated Polyfluoroalkyl Ether Sulfonate (F-53B) Induces Aging and Parkinson’s Disease-like Disorders in C. elegans at Low Concentrations
2025
·
Hui Li
, Keqi Dong
, et al.
·
Environmental Science & Technology
·
16
Behavioral and molecular neurotoxicity of thermally degraded polystyrene in Caenorhabditis elegans
2025
·
Hui Li
, Jinyu Chen
, et al.
·
Journal of Hazardous Materials
·
15
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Works count:
941
Citation count:
1,299
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