Keyword

directing groups

Description: Molecular substituents that guide reagents toward particular sites in chemical reactions, especially transition-metal-catalyzed functionalization of organic molecules.

Primary topic: Catalytic C–H Functionalization Methods (63%)

Wikidata ID: wiki/Q65118350

OpenAlex ID: keywords/directing-groups

Weak Coordination as a Powerful Means for Developing Broadly Useful C–H Functionalization Reactions

2011 · Keary M. Engle, Tian-Sheng Mei, et al. · Accounts of Chemical Research · 2,717

Palladium-Catalyzed Transformations of Alkyl C–H Bonds

2016 · Jian He, Masayuki Wasa, et al. · Chemical Reviews · 2,039

Palladium- and Copper-Catalyzed Arylation of Carbon−Hydrogen Bonds

2009 · Olafs Daugulis, Hien-Quang Do, et al. · Accounts of Chemical Research · 1,986

A comprehensive overview of directing groups applied in metal-catalysed C–H functionalisation chemistry

2018 · Carlo Sambiagio, David Schönbauer, et al. · Chemical Society Reviews · 1,663

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Beyond Directing Groups: Transition‐Metal‐Catalyzed CH Activation of Simple Arenes

2012 · Nadine Kuhl, Matthew N. Hopkinson, et al. · Angewandte Chemie International Edition · 1,636

Transition metal-catalyzed C–H bond functionalizations by the use of diverse directing groups

2015 · Zhengkai Chen, Binjie Wang, et al. · Organic Chemistry Frontiers · 1,535

Controlling Site Selectivity in Palladium-Catalyzed C–H Bond Functionalization

2012 · Sharon R. Neufeldt, Melanie S. Sanford · Accounts of Chemical Research · 1,360

Catalytic C–C Bond Activations via Oxidative Addition to Transition Metals

2015 · Laetitia Souillart, Nicolai Cramer · Chemical Reviews · 1,113

Catalytic C−H/Olefin Coupling

2002 · Fumitoshi Kakiuchi, Shinji Murai · Accounts of Chemical Research · 1,090

A Highly Selective Catalytic Method for the Oxidative Functionalization of C−H Bonds

2004 · Allison R. Dick, Kami L. Hull, et al. · Journal of the American Chemical Society · 1,057

Substrate Activation Strategies in Rhodium(III)-Catalyzed Selective Functionalization of Arenes

2015 · Guoyong Song, Xingwei Li · Accounts of Chemical Research · 988

Rhodium(III)-Catalyzed Heterocycle Synthesis Using an Internal Oxidant: Improved Reactivity and Mechanistic Studies

2011 · Nicolas Guimond, Serge I. Gorelsky, et al. · Journal of the American Chemical Society · 941

Iron-Catalyzed C–H Bond Activation

2017 · Rui Shang, Laurean Ilies, et al. · Chemical Reviews · 924

C–H Activation: Toward Sustainability and Applications

2021 · Toryn Dalton, Teresa Faber, et al. · ACS Central Science · 834

Oxidative C−H Activation/C−C Bond Forming Reactions: Synthetic Scope and Mechanistic Insights

2005 · Dipannita Kalyani, Nicholas R. Deprez, et al. · Journal of the American Chemical Society · 796

Site-Selective C–H Functionalization via Synergistic Use of Electrochemistry and Transition Metal Catalysis

2020 · Ke-Jin Jiao, Yi-Kang Xing, et al. · Accounts of Chemical Research · 763

Rh(III)-Catalyzed Directed C−H Olefination Using an Oxidizing Directing Group: Mild, Efficient, and Versatile

2011 · Souvik Rakshit, Christoph Grohmann, et al. · Journal of the American Chemical Society · 763

Room-Temperature C–H Arylation: Merger of Pd-Catalyzed C–H Functionalization and Visible-Light Photocatalysis

2011 · Dipannita Kalyani, Kate B. McMurtrey, et al. · Journal of the American Chemical Society · 676

Complementary Strategies for Directed C(sp 3 )−H Functionalization: A Comparison of Transition‐Metal‐Catalyzed Activation, Hydrogen Atom Transfer, and Carbene/Nitrene Transfer

2017 · John C. K. Chu, Tomislav Rovis · Angewandte Chemie International Edition · 670

Arene C–H functionalisation using a removable/modifiable or a traceless directing group strategy

2014 · Fengzhi Zhang, David R. Spring · Chemical Society Reviews · 638

Computational Studies of Carboxylate-Assisted C–H Activation and Functionalization at Group 8–10 Transition Metal Centers

2017 · David L. Davies, Stuart A. Macgregor, et al. · Chemical Reviews · 586

Recent advances in directed C–H functionalizations using monodentate nitrogen-based directing groups

2014 · Min Zhang, Yuanfei Zhang, et al. · Organic Chemistry Frontiers · 568

Innate and Guided C–H Functionalization Logic

2011 · Tobias Brückl, Ryan D. Baxter, et al. · Accounts of Chemical Research · 551

sp2 C–H bond activation in water and catalytic cross-coupling reactions

2013 · Bin Li, Pierre H. Dixneuf · Chemical Society Reviews · 542

Transition-Metal-Catalyzed, Coordination-Assisted Functionalization of Nonactivated C(sp 3 )–H Bonds

2021 · Bin Liu, Andrew M. Romine, et al. · Chemical Reviews · 540

Works count: 2,055

Citation count: 99,410