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DMRT1
Description:
A protein-coding gene encoding a transcription factor involved in gonadal development and sex determination in vertebrates.
Primary topic:
Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities (48%)
Related topics:
Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities (48%),
Reproductive biology and impacts on aquatic species (29%)
Wikidata ID:
wiki/Q17914024
OpenAlex ID:
keywords/dmrt1
The avian Z-linked gene DMRT1 is required for male sex determination in the chicken
2009
·
Craig A. Smith
, Kelly N. Roeszler
, et al.
·
Nature
·
857
A duplicated copy of DMRT1 in the sex-determining region of the Y chromosome of the medaka, Oryzias latipes
2002
·
Indrajit Nanda
, Mariko Kondo
, et al.
·
Proceedings of the National Academy of Sciences
·
849
Whole-genome sequence of a flatfish provides insights into ZW sex chromosome evolution and adaptation to a benthic lifestyle
2014
·
Songlin Chen
, Guojie Zhang
, et al.
·
Nature Genetics
·
822
PDF
Ovarian aromatase and estrogens: A pivotal role for gonadal sex differentiation and sex change in fish
2009
·
Yann Guiguen
, Alexis Fostier
, et al.
·
General and Comparative Endocrinology
·
712
Dmrt1 , a gene related to worm and fly sexual regulators, is required for mammalian testis differentiation
2000
·
Christopher S. Raymond
, Mark W. Murphy
, et al.
·
Genes & Development
·
671
PDF
DMRT1 prevents female reprogramming in the postnatal mammalian testis
2011
·
Clinton K. Matson
, Mark W. Murphy
, et al.
·
Nature
·
635
A W-linked DM-domain gene, DM-W, participates in primary ovary development in Xenopus laevis
2008
·
Shin Yoshimoto
, Ema Okada
, et al.
·
Proceedings of the National Academy of Sciences
·
507
Expression of Dmrt1 in the Genital Ridge of Mouse and Chicken Embryos Suggests a Role in Vertebrate Sexual Development
1999
·
Christopher S. Raymond
, Jae R. Kettlewell
, et al.
·
Developmental Biology
·
491
PDF
Antagonists to the Wnt Cascade Exhibit Sex-Specific Expression in Gonads of Sexually Mature Shovelnose Sturgeon
2013
·
J.J. Amberg
, R.R. Goforth
, et al.
·
Sexual Development
·
477
PDF
Sexual Dimorphic Expression of Genes in Gonads During Early Differentiation of a Teleost Fish, the Nile Tilapia Oreochromis niloticus1
2007
·
Shigeho Ijiri
, Hiroyo Kaneko
, et al.
·
Biology of Reproduction
·
411
PDF
Sex and the singular DM domain: insights into sexual regulation, evolution and plasticity
2012
·
Clinton K. Matson
, David Zarkower
·
Nature Reviews Genetics
·
410
Conservation of a sex-determining gene
1999
·
Craig A. Smith
, Peter J. McClive
, et al.
·
Nature
·
396
The Mammalian Doublesex Homolog DMRT1 Is a Transcriptional Gatekeeper that Controls the Mitosis versus Meiosis Decision in Male Germ Cells
2010
·
Clinton K. Matson
, Mark W. Murphy
, et al.
·
Developmental Cell
·
368
PDF
Sex determination: insights from the chicken
2004
·
Craig A. Smith
, Andrew H. Sinclair
·
BioEssays
·
353
Variants near DMRT1, TERT and ATF7IP are associated with testicular germ cell cancer
2010
·
Clare Turnbull
, Elizabeth A Rapley
, et al.
·
Nature Genetics
·
350
Environmental Effects on Fish Sex Determination and Differentiation
2009
·
J.F. Baroiller
, H. D’Cotta
, et al.
·
Sexual Development
·
345
A region of human chromosome 9p required for testis development contains two genes related to known sexual regulators
1999
·
C. Raymond
·
Human Molecular Genetics
·
345
Two DM domain genes, DMY and DMRT1, involved in testicular differentiation and development in the medaka, Oryzias latipes
2004
·
Tohru Kobayashi
, Masaru Matsuda
, et al.
·
Developmental Dynamics
·
314
Bird-like sex chromosomes of platypus imply recent origin of mammal sex chromosomes
2008
·
Frédéric Veyrunes
, Paul D. Waters
, et al.
·
Genome Research
·
310
PDF
Complex evolutionary trajectories of sex chromosomes across bird taxa
2014
·
Qi Zhou
, Jilin Zhang
, et al.
·
Science
·
307
Dmrt1 is necessary for male sexual development in zebrafish
2016
·
Kaitlyn A. Webster
, Ursula Schach
, et al.
·
Developmental Biology
·
303
Chromatin and Single-Cell RNA-Seq Profiling Reveal Dynamic Signaling and Metabolic Transitions during Human Spermatogonial Stem Cell Development
2017
·
Jingtao Guo
, Edward J. Grow
, et al.
·
Cell stem cell
·
295
PDF
Efficient and Heritable Gene Targeting in Tilapia by CRISPR/Cas9
2014
·
Minghui Li
, Huihui Yang
, et al.
·
Genetics
·
268
PDF
DMRT1 expression during gonadal differentiation and spermatogenesis in the rainbow trout, Oncorhynchus mykiss
2000
·
Oriane Marchand
, Marina Govoroun
, et al.
·
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression
·
268
Novel sex‐determining genes in fish and sex chromosome evolution
2013
·
Kiyoshi Kikuchi
, Satoshi Hamaguchi
·
Developmental Dynamics
·
265
PDF
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Works count:
1,498
Citation count:
47,030
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