Keyword

DNA binding

Description: A molecular interaction in which a protein or other molecule associates selectively and non-covalently with DNA, often affecting gene activity.

Primary topic: Metal complexes synthesis and properties (25%)

Wikidata ID: wiki/Q14633858

OpenAlex ID: keywords/dna-binding

Jak-STAT Pathways and Transcriptional Activation in Response to IFNs and Other Extracellular Signaling Proteins

1994 · James E. Darnell, lan M. Kerr, et al. · Science · 6,068

Relationships between the carbon-oxygen stretching frequencies of carboxylato complexes and the type of carboxylate coordination

1980 · G Deacon · Coordination Chemistry Reviews · 5,134

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

1995 · Miyashita Toshiyuki, John C Reed · Cell · 4,062

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Peroxisome Proliferator-Activated Receptors: Nuclear Control of Metabolism

1999 · Béatrice Desvergne, Walter Wahli · Endocrine Reviews · 3,091

Crystal Structure of a p53 Tumor Suppressor-DNA Complex: Understanding Tumorigenic Mutations

1994 · Yunje Cho, Svetlana Gorina, et al. · Science · 2,514

A fluorescent complex between ethidium bromide and nucleic acids

1967 · J.-B. Lepecq, C. Paoletti · Journal of Molecular Biology · 2,387

NeuN, a neuronal specific nuclear protein in vertebratesxs

1992 · Richard J. Mullen, Charles R. Buck, et al. · Development · 2,344

A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin

1999 · DavidA Gewirtz · Biochemical Pharmacology · 2,242

Stat3: a STAT Family Member Activated by Tyrosine Phosphorylation in Response to Epidermal Growth Factor and Interleukin-6

1994 · Zhong Zhong, Zilong Wen, et al. · Science · 2,068

A Simple Cipher Governs DNA Recognition by TAL Effectors

2009 · Matthew J. Moscou, Adam J. Bogdanove · Science · 1,992

X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy

2001 · Robert S. Wildin, Fred Ramsdell, et al. · Nature Genetics · 1,922

Recognition and Reaction of Metallointercalators with DNA

1999 · Kathryn E. Erkkila, Duncan T. Odom, et al. · Chemical Reviews · 1,872

Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence

1989 · Cornelis Murre, Patrick Schonleber McCaw, et al. · Cell · 1,815

Steroid Receptor Interactions with Heat Shock Protein and Immunophilin Chaperones

1997 · William B. Pratt, David O. Toft · Endocrine Reviews · 1,791

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DNA interrogation by the CRISPR RNA-guided endonuclease Cas9

2014 · Samuel H. Sternberg, Sy Redding, et al. · Nature · 1,760

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Thermodynamic Fluctuations in a Reacting System—Measurement by Fluorescence Correlation Spectroscopy

1972 · Douglas Magde, Elliot Elson, et al. · Physical Review Letters · 1,755

Liquid droplet formation by HP1α suggests a role for phase separation in heterochromatin

2017 · Adam G. Larson, Daniel Elnatan, et al. · Nature · 1,699

Voltammetric studies of the interaction of metal chelates with DNA. 2. Tris-chelated complexes of cobalt(III) and iron(II) with 1,10-phenanthroline and 2,2'-bipyridine

1989 · Michael T. Carter, Marisol Rodriguez, et al. · Journal of the American Chemical Society · 1,650

Modes of p53 Regulation

2009 · Jan-Philipp Kruse, Wei Gu · Cell · 1,608

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Zinc finger proteins: new insights into structural and functional diversity

2001 · John H Laity, Brian M Lee, et al. · Current Opinion in Structural Biology · 1,534

Complex formation between ethidium bromide and nucleic acids

1965 · M.J. Waring · Journal of Molecular Biology · 1,513

NAC transcription factors: structurally distinct, functionally diverse

2005 · Addie Nina Olsen, Heidi A. Ernst, et al. · Trends in Plant Science · 1,503

Mixed-ligand complexes of ruthenium(II): factors governing binding to DNA

1989 · A. M. Pyle, J. P. Rehmann, et al. · Journal of the American Chemical Society · 1,463

The promoter-specific transcription factor Sp1 binds to upstream sequences in the SV40 early promoter

1983 · William S. Dynan, Robert Tjian · Cell · 1,445

A molecular light switch for DNA: Ru(bpy)2(dppz)2+

1990 · Alan E. Friedman, Jean Claude Chambron, et al. · Journal of the American Chemical Society · 1,413

Works count: 39,620

Citation count: 1,135,000