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Keyword

DNMT1

Description: DNMT1 is a DNA methyltransferase enzyme that maintains DNA methylation patterns and is encoded by a gene in humans and other organisms.
Wikidata ID: wiki/Q14907998
OpenAlex ID: keywords/dnmt1
Epigenetic Reprogramming in Mammalian Development
2001 · Wolf Reik, Wendy Dean, et al. · Science · 3,074
The DNA methyltransferases of mammals
2000 · T. H. Bestor · Human Molecular Genetics · 2,043
Methylation-Induced Repression— Belts, Braces, and Chromatin
1999 · Adrian P Bird, Alan P Wolffe · Cell · 1,827
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CDK4/6 inhibition triggers anti-tumour immunity
2017 · Shom Goel, Molly J. DeCristo, et al. · Nature · 1,506
Induction of Tumors in Mice by Genomic Hypomethylation
2003 · François Gaudet, J. Graeme Hodgson, et al. · Science · 1,499
The DNA methyltransferase family: a versatile toolkit for epigenetic regulation
2017 · Frank Lyko · Nature Reviews Genetics · 1,473
UHRF1 Plays a Role in Maintaining DNA Methylation in Mammalian Cells
2007 · Magnolia Bostick, Jong Kyong Kim, et al. · Science · 1,456
The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA
2007 · Jafar Sharif, Masahiro Muto, et al. · Nature · 1,305
A Critical Role for Dnmt1 and DNA Methylation in T Cell Development, Function, and Survival
2001 · Peggy P. Lee, David R. Fitzpatrick, et al. · Immunity · 1,275
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DNMT1 and DNMT3b cooperate to silence genes in human cancer cells
2002 · Ina Rhee, Kurtis E. Bachman, et al. · Nature · 1,243
Reduced representation bisulfite sequencing for comparative high-resolution DNA methylation analysis
2005 · A. Meissner · Nucleic Acids Research · 1,217
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Epigenetic silencing of TH1-type chemokines shapes tumour immunity and immunotherapy
2015 · Dongjun Peng, Ilona Kryczek, et al. · Nature · 1,197
DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci
2000 · Michael R. Rountree, Kurtis E. Bachman, et al. · Nature Genetics · 1,054
Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons
2010 · Jian Feng, Yu Zhou, et al. · Nature Neuroscience · 1,016
DNA methyltransferase Dnmt1 associates with histone deacetylase activity
2000 · François Fuks, Wendy A. Burgers, et al. · Nature Genetics · 994
Epigenetic Reprogramming and Small RNA Silencing of Transposable Elements in Pollen
2009 · R. Keith Slotkin, Matthew Vaughn, et al. · Cell · 993
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DNA hypomethylation leads to elevated mutation rates
1998 · Richard Z. Chen, Ulf Pettersson, et al. · Nature · 954
DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters
2000 · Keith D. Robertson, Slimane Ait-Si-Ali, et al. · Nature Genetics · 943
Doxorubicin-induced cardiotoxicity: An update on the molecular mechanism and novel therapeutic strategies for effective management
2021 · Pushkar Singh Rawat, Aiswarya Jaiswal, et al. · Biomedicine & Pharmacotherapy · 902
The human DNA methyltransferases (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors
1999 · K. D. Robertson, E. Uzvolgyi, et al. · Nucleic Acids Research · 853
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De novo DNA cytosine methyltransferase activities in mouse embryonic stem cells
1996 · Hong Lei, Suk P. Oh, et al. · Development · 816
The lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylation
2008 · Jing Wang, Sarah Hevi, et al. · Nature Genetics · 815
Loss of FBP1 by Snail-Mediated Repression Provides Metabolic Advantages in Basal-like Breast Cancer
2013 · Chenfang Dong, Tingting Yuan, et al. · Cancer Cell · 804
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MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1
2009 · Ramiro Garzon, Shujun Liu, et al. · Blood · 781
In vivo interrogation of gene function in the mammalian brain using CRISPR-Cas9
2014 · Lukasz Swiech, Matthias Heidenreich, et al. · Nature Biotechnology · 773
Works count: 9,280
Citation count: 295,600
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