Keyword

dosing interval

Description: The time between successive administrations of a medicine, studied in pharmacology and clinical treatment.

Primary topic: Antibiotics Pharmacokinetics and Efficacy (21%)

OpenAlex ID: keywords/dosing-interval

HAWK and HARRIER: Phase 3, Multicenter, Randomized, Double-Masked Trials of Brolucizumab for Neovascular Age-Related Macular Degeneration

2019 · Pravin U. Dugel, Adrian Koh, et al. · Ophthalmology · 925

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Induction and Maintenance Infliximab Therapy for the Treatment of Moderate-to-Severe Crohn’s Disease in Children

2006 · Jeffrey Hyams, Wallace Crandall, et al. · Gastroenterology · 878

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Comparison of ixekizumab with etanercept or placebo in moderate-to-severe psoriasis (UNCOVER-2 and UNCOVER-3): results from two phase 3 randomised trials

2015 · Christopher E M Griffiths, Kristian Reich, et al. · The Lancet · 835

Enhanced antibody half-life improves in vivo activity

2010 · Jonathan Zalevsky, Aaron K Chamberlain, et al. · Nature Biotechnology · 654

Experience with a once-daily aminoglycoside program administered to 2,184 adult patients

1995 · D P Nicolau, C D Freeman, et al. · Antimicrobial Agents and Chemotherapy · 641

Effect of a monoclonal antibody to PCSK9, REGN727/SAR236553, to reduce low-density lipoprotein cholesterol in patients with heterozygous familial hypercholesterolaemia on stable statin dose with or without ezetimibe therapy: a phase 2 randomised controlled trial

2012 · Evan A Stein, Dan Gipe, et al. · The Lancet · 588

Effect of Delta variant on viral burden and vaccine effectiveness against new SARS-CoV-2 infections in the UK

2021 · Koen B. Pouwels, Emma Pritchard, et al. · Nature Medicine · 543

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Withdrawal of Immunosuppression in Crohn's Disease Treated With Scheduled Infliximab Maintenance: A Randomized Trial

2008 · Gert Van Assche, Charlotte Magdelaine–Beuzelin, et al. · Gastroenterology · 495

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Factors Affecting the Immunogenicity of Oral Poliovirus Vaccine in Developing Countries: Review

1991 · P. A. Patriarca, P. F. Wright, et al. · Clinical Infectious Diseases · 454

The relationship of serum infliximab concentrations to clinical improvement in rheumatoid arthritis: Results from ATTRACT, a multicenter, randomized, double‐blind, placebo‐controlled trial

2002 · E. William St.Clair, Carrie L. Wagner, et al. · Arthritis & Rheumatism · 417

Ixekizumab for the treatment of patients with active psoriatic arthritis and an inadequate response to tumour necrosis factor inhibitors: results from the 24-week randomised, double-blind, placebo-controlled period of the SPIRIT-P2 phase 3 trial

2017 · Peter Nash, Bruce Kirkham, et al. · The Lancet · 405

Spike-antibody waning after second dose of BNT162b2 or ChAdOx1

2021 · Madhumita Shrotri, Annalan M D Navaratnam, et al. · The Lancet · 393

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Effect of Longer-Interval vs Standard Dosing of Zoledronic Acid on Skeletal Events in Patients With Bone Metastases

2017 · Andrew L. Himelstein, Jared C. Foster, et al. · JAMA · 355

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Comparative Antibiotic Dose-Effect Relations at Several Dosing Intervals in Murine Pneumonitis and Thigh-Infection Models

1989 · J. E. Leggett, B. Fantin, et al. · The Journal of Infectious Diseases · 354

Large-scale Field Trial of Ty21a Live Oral Typhoid Vaccine in Enteric-coated Capsule Formulation

1987 · MyronM Levine, RobertE Black, et al. · The Lancet · 352

Compliance with Topical Pilocarpine Treatment

1986 · Michael A. Kass, David W. Meltzer, et al. · American Journal of Ophthalmology · 342

Secukinumab in moderate-to-severe hidradenitis suppurativa (SUNSHINE and SUNRISE): week 16 and week 52 results of two identical, multicentre, randomised, placebo-controlled, double-blind phase 3 trials

2023 · Alexa B Kimball, Gregor B E Jemec, et al. · The Lancet · 340

Guselkumab in patients with active psoriatic arthritis who were biologic-naive or had previously received TNFα inhibitor treatment (DISCOVER-1): a double-blind, randomised, placebo-controlled phase 3 trial

2020 · Atul Deodhar, Philip S Helliwell, et al. · The Lancet · 331

Tralokinumab plus topical corticosteroids for the treatment of moderate‐to‐severe atopic dermatitis: results from the double‐blind, randomized, multicentre, placebo‐controlled phase III ECZTRA 3 trial*

2020 · J.I. Silverberg, D. Toth, et al. · British Journal of Dermatology · 327

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Once-daily aminoglycoside therapy

1991 · D N Gilbert · Antimicrobial Agents and Chemotherapy · 324

Predictors of enhanced response with benralizumab for patients with severe asthma: pooled analysis of the SIROCCO and CALIMA studies

2017 · J Mark FitzGerald, Eugene R Bleecker, et al. · The Lancet Respiratory Medicine · 319

Procainamide Dosage Schedules, Plasma Concentrations, and Clinical Effects

1971 · Jan Koch-Weser · JAMA · 319

Issues in Pharmacokinetics and Pharmacodynamics of Anti-Infective Agents: Kill Curves versus MIC

2004 · Markus Mueller, Amparo de la Peña, et al. · Antimicrobial Agents and Chemotherapy · 304

To err is human: Patient misinterpretations of prescription drug label instructions

2007 · Michael S. Wolf, Terry C. Davis, et al. · Patient Education and Counseling · 296

Differential Effects of Omeprazole and Pantoprazole on the Pharmacodynamics and Pharmacokinetics of Clopidogrel in Healthy Subjects: Randomized, Placebo-Controlled, Crossover Comparison Studies

2010 · D J Angiolillo, C M Gibson, et al. · Clinical Pharmacology & Therapeutics · 282

Works count: 3,675

Citation count: 63,120