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Keyword

DPP9

Description: Dipeptidyl peptidase 9 is an intracellular enzyme that cleaves amino-terminal dipeptides and is studied in enzymology and disease biology.
OpenAlex ID: keywords/dpp9
Genetic mechanisms of critical illness in COVID-19
2020 · The GenOMICC Investigators, Erola Pairo-Castineira, et al. · Nature · 1,367
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Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis
2013 · Tasha E Fingerlin, Elissa Murphy, et al. · Nature Genetics · 806
DPP8 and DPP9 inhibition induces pro-caspase-1-dependent monocyte and macrophage pyroptosis
2016 · Marian C Okondo, Darren C Johnson, et al. · Nature Chemical Biology · 290
Extended Structure–Activity Relationship and Pharmacokinetic Investigation of (4-Quinolinoyl)glycyl-2-cyanopyrrolidine Inhibitors of Fibroblast Activation Protein (FAP)
2014 · Koen Jansen, Leen Heirbaut, et al. · Journal of Medicinal Chemistry · 288
Prolyl peptidases: a serine protease subfamily with high potential for drug discovery
2003 · Jonathan S Rosenblum, John W Kozarich · Current Opinion in Chemical Biology · 284
Cloning, expression and chromosomal localization of a novel human dipeptidyl peptidase (DPP) IV homolog, DPP8
2000 · Catherine A. Abbott, Denise M. T. Yu, et al. · European Journal of Biochemistry · 271
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Human DPP9 represses NLRP1 inflammasome and protects against autoinflammatory diseases via both peptidase activity and FIIND domain binding
2018 · Franklin L. Zhong, Kim Robinson, et al. · Journal of Biological Chemistry · 242
Dipeptidyl peptidase inhibitors, an emerging drug class for inflammatory disease?
2009 · Roger Yazbeck, Gordon S. Howarth, et al. · Trends in Pharmacological Sciences · 241
Genetic mechanisms of critical illness in Covid-19
2020 · Erola Pairo-Castineira, Sara Clohisey, et al. · medRxiv · 236
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DPP9 sequesters the C terminus of NLRP1 to repress inflammasome activation
2021 · L. Robert Hollingsworth, Humayun Sharif, et al. · Nature · 203
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Genome-wide analysis provides genetic evidence that ACE2 influences COVID-19 risk and yields risk scores associated with severe disease
2022 · Julie E. Horowitz, Jack A. Kosmicki, et al. · Nature Genetics · 202
CD26/DPP4 - a potential biomarker and target for cancer therapy
2019 · Njanja Enz, Gwendolyn Vliegen, et al. · Pharmacology & Therapeutics · 194
The Dipeptidyl Peptidase Family, Prolyl Oligopeptidase, and Prolyl Carboxypeptidase in the Immune System and Inflammatory Disease, Including Atherosclerosis
2015 · Yannick Waumans, Lesley Baerts, et al. · Frontiers in Immunology · 194
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The NLRP1 and CARD8 inflammasomes
2020 · Cornelius Y. Taabazuing, Andrew R. Griswold, et al. · Immunological Reviews · 180
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CARD8 inflammasome activation triggers pyroptosis in human T cells
2020 · Andreas Linder, Stefan Bauernfried, et al. · The EMBO Journal · 178
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Cloning and characterization of dipeptidyl peptidase 10, a new member of an emerging subgroup of serine proteases
2003 · Shu Y. QI, Pierre J. RIVIERE, et al. · Biochemical Journal · 151
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Structural and biochemical mechanisms of NLRP1 inhibition by DPP9
2021 · Menghang Huang, Xiaoxiao Zhang, et al. · Nature · 143
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Identification and characterization of human DPP9 , a novel homologue of dipeptidyl peptidase IV
2002 · Christina Olsen, Nicolai Wagtmann · Gene · 140
Dipeptidyl peptidase 9 has two forms, a broad tissue distribution, cytoplasmic localization and DPIV-like peptidase activity
2004 · Katerina Ajami, Catherine A Abbott, et al. · Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression · 137
Dipeptidyl peptidases 8 and 9: specificity and molecular characterization compared with dipeptidyl peptidase IV
2006 · Jais R. Bjelke, Jesper Christensen, et al. · Biochemical Journal · 123
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The Cytoplasmic Peptidase DPP9 Is Rate-limiting for Degradation of Proline-containing Peptides
2009 · Ruth Geiss-Friedlander, Nicolas Parmentier, et al. · Journal of Biological Chemistry · 120
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P38 kinases mediate NLRP1 inflammasome activation after ribotoxic stress response and virus infection
2022 · Lea-Marie Jenster, Karl-Elmar Lange, et al. · The Journal of Experimental Medicine · 115
Unravelling the immunological roles of dipeptidyl peptidase 4 (DPP4) activity and/or structure homologue (DASH) proteins
2015 · L Wagner, C Klemann, et al. · Clinical & Experimental Immunology · 113
Adverse effects of dipeptidyl peptidases 8 and 9 inhibition in rodents revisited
2008 · B. F. Burkey, P. K. Hoffmann, et al. · Diabetes Obesity and Metabolism · 110
DPP9 Stabilizes NRF2 to Suppress Ferroptosis and Induce Sorafenib Resistance in Clear Cell Renal Cell Carcinoma
2023 · Kun Chang, Yingji Chen, et al. · Cancer Research · 106
Works count: 382
Citation count: 11,240
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