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Keyword

DRG1

Description: A human protein-coding gene encoding a GTPase involved in cellular processes including translation and ribosome biogenesis.
Wikidata ID: wiki/Q18030003
OpenAlex ID: keywords/drg1
A novel gene which is up-regulated during colon epithelial cell differentiation and down-regulated in colorectal neoplasms.
1997 · N van Belzen, W N Dinjens, et al. · PubMed · 254
Identification of New Genes Ndr2 and Ndr3 Which Are Related to Ndr1/RTP/Drg1 but Show Distinct Tissue Specificity and Response to N-myc
1999 · Tomohiko Okuda, Hisato Kondoh · Biochemical and Biophysical Research Communications · 125
Cytoplasmic Recycling of 60S Preribosomal Factors Depends on the AAA Protein Drg1
2007 · Brigitte Pertschy, Cosmin Saveanu, et al. · Molecular and Cellular Biology · 109
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A Phase I Clinical Trial of the Sequential Combination of Irinotecan Followed by Flavopiridol
2005 · Manish A. Shah, Jeremy Kortmansky, et al. · Clinical Cancer Research · 101
The differentiation‐related gene 1, Drg1, is markedly upregulated by androgens in LNCaP prostatic adenocarcinoma cells
1999 · William Ulrix, Johannes V. Swinnen, et al. · FEBS Letters · 92
The power of AAA-ATPases on the road of pre-60S ribosome maturation — Molecular machines that strip pre-ribosomal particles
2011 · Dieter Kressler, Ed Hurt, et al. · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · 87
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Rlp24 activates the AAA-ATPase Drg1 to initiate cytoplasmic pre-60S maturation
2012 · Lisa Kappel, Mathias Loibl, et al. · The Journal of Cell Biology · 79
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Discovery and characterization of nutritionally regulated genes associated with muscle growth in Atlantic salmon
2010 · Neil I. Bower, Ian A. Johnston · Physiological Genomics · 67
DRG represents a family of two closely related GTP-binding proteins
2000 · Bo Li, Beat Trueb · Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression · 66
Drg1 Expression in 131 Colorectal Liver Metastases: Correlation with Clinical Variables and Patient Outcomes
2005 · Manish A. Shah, Nancy Kemeny, et al. · Clinical Cancer Research · 64
The Drug Diazaborine Blocks Ribosome Biogenesis by Inhibiting the AAA-ATPase Drg1
2013 · Mathias Loibl, Isabella Klein, et al. · Journal of Biological Chemistry · 61
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Expression of differentiation-related genes in colorectal cancer: possible implications for prognosis.
1998 · N van Belzen, W N Dinjens, et al. · PubMed · 60
Identification of DRG family regulatory proteins (DFRPs): specific regulation of DRG1 and DRG2
2005 · Kosuke Ishikawa, Sakura Azuma, et al. · Genes to Cells · 59
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m6A-dependent up-regulation of DRG1 by METTL3 and ELAVL1 promotes growth, migration, and colony formation in osteosarcoma
2020 · Zhian Ling, Liangjun Chen, et al. · Bioscience Reports · 58
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Seven genes that are differentially transcribed in colorectal tumor cell lines
2000 · Inko Nimmrich, Silke Erdmann, et al. · Cancer Letters · 58
Function of Drg1/Rit42 in p53-dependent Mitotic Spindle Checkpoint
2004 · Kyung-tae Kim, Pat P. Ongusaha, et al. · Journal of Biological Chemistry · 57
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Drg1, a novel target for modulating sensitivity to CPT-11 in colon cancer cells.
2002 · Monica Motwani, Francis M Sirotnak, et al. · PubMed · 57
The Jumonji-C oxygenase JMJD7 catalyzes (3S)-lysyl hydroxylation of TRAFAC GTPases
2018 · Suzana Markolovic, Qinqin Zhuang, et al. · Nature Chemical Biology · 43
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Shaping the Nascent Ribosome: AAA-ATPases in Eukaryotic Ribosome Biogenesis
2019 · Michael Prattes, Yu-Hua Lo, et al. · Biomolecules · 42
Structure of the Human Protein Kinase MPSK1 Reveals an Atypical Activation Loop Architecture
2008 · Jeyanthy Eswaran, Antonio Bernad, et al. · Structure · 35
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Male infertility‐associated Ccdc108 regulates multiciliogenesis via the intraflagellar transport machinery
2022 · Huijie Zhao, Jian Sun, et al. · EMBO Reports · 34
Developmentally Regulated GTP binding protein 1 (DRG1) controls microtubule dynamics
2017 · Anna Katharina Schellhaus, Daniel Moreno-Andrés, et al. · Scientific Reports · 32
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Ubc9 fusion-directed SUMOylation identifies constitutive and inducible SUMOylation
2007 · A. Jakobs, F. Himstedt, et al. · Nucleic Acids Research · 31
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Conserved heterodimeric GTPase Rbg1/Tma46 promotes efficient translation in eukaryotic cells
2021 · Fuxing Zeng, Xin Li, et al. · Cell Reports · 30
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Independent stabilizations of polysomal Drg1/Dfrp1 complex and non-polysomal Drg2/Dfrp2 complex in mammalian cells
2009 · Kosuke Ishikawa, Taishin Akiyama, et al. · Biochemical and Biophysical Research Communications · 30
Works count: 149
Citation count: 2,117
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