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Keyword

driver mutations

Description: Driver mutations are genetic changes that give a cell or cellular clone a selective advantage, promoting its survival or reproduction, particularly in cancer.
Wikidata ID: wiki/Q16570960
OpenAlex ID: keywords/driver-mutations
Cancer Genome Landscapes
2013 · Bert Vogelstein, Nickolas Papadopoulos, et al. · Science · 7,818
The Immune Landscape of Cancer
2018 · Vésteinn Thorsson, Vésteinn Thorsson, et al. · Immunity · 5,739
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Mutational heterogeneity in cancer and the search for new cancer-associated genes
2013 · Michael S. Lawrence, Petar Stojanov, et al. · Nature · 5,458
Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia
2013 · The Cancer Genome Atlas Research Network · New England Journal of Medicine · 5,061
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Determining cell type abundance and expression from bulk tissues with digital cytometry
2019 · Aaron M. Newman, Chloé B. Steen, et al. · Nature Biotechnology · 4,481
Mutational landscape and significance across 12 major cancer types
2013 · Cyriac Kandoth, Michael D. McLellan, et al. · Nature · 4,408
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Genomic Classification and Prognosis in Acute Myeloid Leukemia
2016 · Elli Papaemmanuil, Moritz Gerstung, et al. · New England Journal of Medicine · 4,329
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Oncogenic Signaling Pathways in The Cancer Genome Atlas
2018 · Francisco Sanchez-Vega, Marco Mina, et al. · Cell · 3,175
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Patterns of somatic mutation in human cancer genomes
2007 · Christopher Greenman, Philip Stephens, et al. · Nature · 3,081
Integrated Genomic Characterization of Papillary Thyroid Carcinoma
2014 · Nishant Agrawal, Rehan Akbani, et al. · Cell · 3,063
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A Landscape of Driver Mutations in Melanoma
2012 · Eran Hodis, Ian R. Watson, et al. · Cell · 2,604
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Hepatocellular carcinoma
2016 · Josep M. Llovet, Jessica Zucman-Rossi, et al. · Nature Reviews Disease Primers · 2,528
Tracking the Evolution of Non–Small-Cell Lung Cancer
2017 · Mariam Jamal-Hanjani, Gareth A. Wilson, et al. · New England Journal of Medicine · 2,338
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Comprehensive Characterization of Cancer Driver Genes and Mutations
2018 · Matthew H. Bailey, Collin Tokheim, et al. · Cell · 2,298
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Landscape of somatic mutations in 560 breast cancer whole-genome sequences
2016 · Serena Nik-Zainal, Helen Davies, et al. · Nature · 2,211
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Predicting the functional impact of protein mutations: application to cancer genomics
2011 · Boris Reva, Yevgeniy Antipin, et al. · Nucleic Acids Research · 2,002
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Clinical and biological implications of driver mutations in myelodysplastic syndromes
2013 · Elli Papaemmanuil, Moritz Gerstung, et al. · Blood · 1,832
The landscape of cancer genes and mutational processes in breast cancer
2012 · Philip J. Stephens, Patrick S. Tarpey, et al. · Nature · 1,698
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A comprehensive catalogue of somatic mutations from a human cancer genome
2009 · Erin D. Pleasance, R. Keira Cheetham, et al. · Nature · 1,695
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Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma
2011 · Ryan D. Morin, Maria Mendez-Lago, et al. · Nature · 1,609
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Universal Patterns of Selection in Cancer and Somatic Tissues
2017 · Iñigo Martincorena, Keiran M. Raine, et al. · Cell · 1,515
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High-throughput screening using patient-derived tumor xenografts to predict clinical trial drug response
2015 · Hui Gao, Joshua M Korn, et al. · Nature Medicine · 1,386
Evolution and Impact of Subclonal Mutations in Chronic Lymphocytic Leukemia
2013 · Dan A. Landau, Scott L. Carter, et al. · Cell · 1,380
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Mutational Analysis Reveals the Origin and Therapy-Driven Evolution of Recurrent Glioma
2013 · Brett E. Johnson, Tali Mazor, et al. · Science · 1,356
Epigenetic plasticity and the hallmarks of cancer
2017 · William A. Flavahan, Elizabeth Gaskell, et al. · Science · 1,329
Works count: 9,821
Citation count: 276,600
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