Keyword

Drp1

Description: A mitochondrial fission protein, encoded by the DNM1L gene, that helps divide mitochondria and is studied in cellular and disease biology.

Primary topic: Mitochondrial Function and Pathology (40%)

Wikidata ID: wiki/Q18034992

OpenAlex ID: keywords/drp1

Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

2008 · Gilad Twig, Alvaro Elorza, et al. · The EMBO Journal · 3,079

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ER Tubules Mark Sites of Mitochondrial Division

2011 · Jonathan R. Friedman, Laura L. Lackner, et al. · Science · 2,070

Dynasore, a Cell-Permeable Inhibitor of Dynamin

2006 · Eric Macia, Marcelo Ehrlich, et al. · Developmental Cell · 2,037

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2001 · Elena Smirnova, Lorena Griparic, et al. · Molecular Biology of the Cell · 1,934

The Role of Dynamin-Related Protein 1, a Mediator of Mitochondrial Fission, in Apoptosis

2001 · Stephan Frank, Brigitte Gaume, et al. · Developmental Cell · 1,753

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During autophagy mitochondria elongate, are spared from degradation and sustain cell viability

2011 · Ligia C. Gomes, Giulietta Di Benedetto, et al. · Nature Cell Biology · 1,732

The Importance of Dendritic Mitochondria in the Morphogenesis and Plasticity of Spines and Synapses

2004 · Zheng Li, Ken-Ichi Okamoto, et al. · Cell · 1,497

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Mitochondrial dynamics: overview of molecular mechanisms

2018 · Lisa Tilokani, Shun Nagashima, et al. · Essays in Biochemistry · 1,394

Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin

2010 · Atsushi Tanaka, Megan M. Cleland, et al. · The Journal of Cell Biology · 1,366

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Mitochondrial energetics in the kidney

2017 · Pallavi Bhargava, Rick G. Schnellmann · Nature Reviews Nephrology · 1,343

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Mitotic Phosphorylation of Dynamin-related GTPase Drp1 Participates in Mitochondrial Fission

2007 · Naoko Taguchi, Naotada Ishihara, et al. · Journal of Biological Chemistry · 1,236

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Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fission

2013 · Oliver C. Losón, Zhiyin Song, et al. · Molecular Biology of the Cell · 1,232

Impaired Balance of Mitochondrial Fission and Fusion in Alzheimer's Disease

2009 · X. Wang, B. Su, et al. · Journal of Neuroscience · 1,225

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Chemical Inhibition of the Mitochondrial Division Dynamin Reveals Its Role in Bax/Bak-Dependent Mitochondrial Outer Membrane Permeabilization

2008 · Ann Cassidy-Stone, Jerry E. Chipuk, et al. · Developmental Cell · 1,196

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Tubular network formation protects mitochondria from autophagosomal degradation during nutrient starvation

2011 · Angelika S. Rambold, Brenda Kostelecky, et al. · Proceedings of the National Academy of Sciences · 1,157

Dephosphorylation by calcineurin regulates translocation of Drp1 to mitochondria

2008 · G. M. Cereghetti, A. Stangherlin, et al. · Proceedings of the National Academy of Sciences · 1,129

Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells

2010 · Hidenori Otera, Chunxin Wang, et al. · The Journal of Cell Biology · 1,106

S-Nitrosylation of Drp1 Mediates β-Amyloid-Related Mitochondrial Fission and Neuronal Injury

2009 · Dong-Hyung Cho, Tomohiro Nakamura, et al. · Science · 1,088

AMP-activated protein kinase mediates mitochondrial fission in response to energy stress

2016 · Erin Quan Toyama, Sébastien Herzig, et al. · Science · 1,079

Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice

2009 · Naotada Ishihara, Masatoshi Nomura, et al. · Nature Cell Biology · 1,066

Roles of the Mammalian Mitochondrial Fission and Fusion Mediators Fis1, Drp1, and Opa1 in Apoptosis

2004 · Yang-ja Lee, Seon-Yong Jeong, et al. · Molecular Biology of the Cell · 1,042

Reversible phosphorylation of Drp1 by cyclic AMP‐dependent protein kinase and calcineurin regulates mitochondrial fission and cell death

2007 · J Thomas Cribbs, Stefan Strack · EMBO Reports · 1,020

Control of mitochondrial morphology by a human mitofusin

2001 · Ansgar Santel, Margaret T. Fuller · Journal of Cell Science · 1,013

Inhibiting Mitochondrial Fission Protects the Heart Against Ischemia/Reperfusion Injury

2010 · Sang-Bing Ong, Sapna Subrayan, et al. · Circulation · 985

Loss of PINK1 Function Promotes Mitophagy through Effects on Oxidative Stress and Mitochondrial Fission

2009 · Ruben K. Dagda, Salvatore J. Cherra, et al. · Journal of Biological Chemistry · 953

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Works count: 7,410

Citation count: 272,200