Keyword

dynamic binding capacity

Description: A measure of how much target protein a chromatography medium can capture under specified flow conditions before breakthrough occurs.

Primary topic: Protein purification and stability (80%)

OpenAlex ID: keywords/dynamic-binding-capacity

Comparison of protein A affinity sorbents

2003 · Rainer Hahn, Robert Schlegel, et al. · Journal of Chromatography B · 246

Construction of Large-Volume Monolithic Columns

2000 · Aleš Podgornik, Miloš Barut, et al. · Analytical Chemistry · 168

Pore size distributions of ion exchangers and relation to protein binding capacity

2006 · Yan Yao, Abraham M. Lenhoff · Journal of Chromatography A · 159

Development of operating conditions for protein purification using expanded bed techniques: The effect of the degree of bed expansion on adsorption performance

2000 · Y. K. Chang, H. A. Chase · Biotechnology and Bioengineering · 156

Binding capacity differences for antibodies and Fc‐fusion proteins on protein A chromatographic materials

2006 · Sanchayita Ghose, Brian Hubbard, et al. · Biotechnology and Bioengineering · 151

Evaluation of an ion‐exchange membrane for the purification of plasmid DNA

2003 · Heather N. Endres, Julie A. C. Johnson, et al. · Biotechnology and Applied Biochemistry · 129

Protein adsorption and transport in polymer-functionalized ion-exchangers

2011 · Abraham M. Lenhoff · Journal of Chromatography A · 126

High‐Throughput Process Development: Determination of Dynamic Binding Capacity Using Microtiter Filter Plates Filled with Chromatography Resin

2008 · Tryggve Bergander, Kristina Nilsson‐Välimaa, et al. · Biotechnology Progress · 116

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Chitosan–cellulose composite membrane for affinity purification of biopolymers and immunoadsorption

2002 · L. Yang, W.W. Hsiao, et al. · Journal of Membrane Science · 116

Evaluation of recent Protein A stationary phase innovations for capture of biotherapeutics

2018 · Timothy M. Pabst, Johnny Thai, et al. · Journal of Chromatography A · 111

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Performance of hexamer peptide ligands for affinity purification of immunoglobulin G from commercial cell culture media

2010 · Amith D. Naik, Stefano Menegatti, et al. · Journal of Chromatography A · 101

Fabrication of high-permeability and high-capacity monolith for protein chromatography

2007 · Kai-Feng Du, Dong Yang, et al. · Journal of Chromatography A · 93

Properties and Characterization of High Capacity Resins for Biochromatography

2005 · E. Müller · Chemical Engineering & Technology · 92

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Characterization of methacrylate monoliths for purification of DNA molecules

2004 · Mojca Benčina, Aleš Podgornik, et al. · Journal of Separation Science · 92

Industrial case study: Evaluation of a mixed-mode resin for selective capture of a human growth factor recombinantly expressed in E. coli

2009 · Kimberly A. Kaleas, Charles H. Schmelzer, et al. · Journal of Chromatography A · 90

Some preparative and analytical applications of triazine dyes

1981 · C.R. Lowe, D.A.P. Small, et al. · International Journal of Biochemistry · 89

IgG adsorption on a new protein A adsorbent based on macroporous hydrophilic polymers. I. Adsorption equilibrium and kinetics

2009 · Ernie X. Perez-Almodovar, Giorgio Carta · Journal of Chromatography A · 86

Efficient Polymer Monolith for Strong Cation-Exchange Capillary Liquid Chromatography of Peptides

2006 · Binghe Gu, Zhaoyuan Chen, et al. · Analytical Chemistry · 86

Preparation and characterization of novel macroporous cellulose beads regenerated from ionic liquid for fast chromatography

2009 · Kai-Feng Du, Min Yan, et al. · Journal of Chromatography A · 84

A rapid method for determining dynamic binding capacity of resins for the purification of proteins

2008 · Tri Do, Frank Ho, et al. · Protein Expression and Purification · 83

Dynamic Capacity Studies of CIM (Convective Interaction Media)® Monolithic Columns

2000 · Igor Mihelič, Tine Koloini, et al. · Journal of High Resolution Chromatography · 77

Development of operating conditions for protein purification using expanded bed techniques: The effect of the degree of bed expansion on adsorption performance

1996 · Y. K. Chang, H. A. Chase · Biotechnology and Bioengineering · 77

Development of high-productivity, strong cation-exchange adsorbers for protein capture by graft polymerization from membranes with different pore sizes

2012 · Heather C.S. Chenette, Julie R. Robinson, et al. · Journal of Membrane Science · 76

Protein adsorption and transport in dextran-modified ion-exchange media. II. Intraparticle uptake and column breakthrough

2011 · Brian D. Bowes, Abraham M. Lenhoff · Journal of Chromatography A · 75

Ion exchange chromatography of monoclonal antibodies: Effect of resin ligand density on dynamic binding capacity

2008 · Ann Marie Hardin, Chithkala Harinarayan, et al. · Journal of Chromatography A · 74

Works count: 445

Citation count: 9,794