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Keyword

ebselen

Description: Ebselen is a synthetic organoselenium compound studied for antioxidant, anti-inflammatory, and pharmacological effects in biomedical research.
Wikidata ID: wiki/Q5332073
OpenAlex ID: keywords/ebselen
Free Radicals in Biology and Medicine
2015 · Barry Halliwell, John M. C. Gutteridge · Oxford University Press eBooks · 8,979
Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors
2020 · Zhenming Jin, Xiaoyu Du, et al. · Nature · 4,365
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Mitochondrial reactive oxygen species trigger hypoxia-induced transcription
1998 · N. S. Chandel, E. Maltepe, et al. · Proceedings of the National Academy of Sciences · 1,925
Oxidative chemistry of nitric oxide: the roles of superoxide, peroxynitrite, and carbon dioxide
1998 · Giuseppe L. Squadrito, William A. Pryor · Free Radical Biology and Medicine · 795
Ebselen in Acute Ischemic Stroke
1998 · Takenori Yamaguchi, Keiji Sano, et al. · Stroke · 615
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Functional Mimics of Glutathione Peroxidase: Bioinspired Synthetic Antioxidants
2010 · Krishna P. Bhabak, Govindasamy Mugesh · Accounts of Chemical Research · 543
Antioxidant Function of Thioredoxin and Glutaredoxin Systems
2000 · Arne Holmgren · Antioxidants and Redox Signaling · 503
Glutathione Peroxidase Protects against Peroxynitrite-mediated Oxidations
1997 · Helmut Sies, Victor S. Sharov, et al. · Journal of Biological Chemistry · 488
Ebselen, a selenoorganic compound as glutathione peroxidase mimic
1993 · Helmut Sies · Free Radical Biology and Medicine · 432
Transcriptional and Posttranscriptional Regulation of Endothelial Nitric Oxide Synthase Expression by Hydrogen Peroxide
2000 · Grant R. Drummond, Hua Cai, et al. · Circulation Research · 430
Molecular actions of Ebselen—an antiinflammatory antioxidant
1995 · Tankred Schewe · General Pharmacology The Vascular System · 429
Current and Emerging Topical Antibacterials and Antiseptics: Agents, Action, and Resistance Patterns
2017 · Deborah A. Williamson, Glen P. Carter, et al. · Clinical Microbiology Reviews · 375
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Doxorubicin-induced Apoptosis in Endothelial Cells and Cardiomyocytes Is Ameliorated by Nitrone Spin Traps and Ebselen
2000 · Srigiridhar Kotamraju, Eugene A. Konorev, et al. · Journal of Biological Chemistry · 372
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Oxidative and nitrosative stress in acute renal ischemia
2001 · Eisei Noiri, Akihide Nakao, et al. · American Journal of Physiology-Renal Physiology · 366
Drug Antioxidant Effects
1991 · Barry Halliwell · Drugs · 354
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Ebselen, a promising antioxidant drug: mechanisms of action and targets of biological pathways
2014 · Gajendra Kumar Azad, Raghuvir S. Tomar · Molecular Biology Reports · 343
Bile acid-induced rat hepatocyte apoptosis is inhibited by antioxidants and blockers of the mitochondrial permeability transition
2001 · B Yerushalmi · Hepatology · 339
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Selenoproteins: Antioxidant selenoenzymes and beyond
2016 · Holger Steinbrenner, Bodo Speckmann, et al. · Archives of Biochemistry and Biophysics · 327
Peroxynitrite Scavenging by Flavonoids
1997 · Guido R.M.M. Haenen, Jos B.G. Paquay, et al. · Biochemical and Biophysical Research Communications · 322
Sirt3 Impairment and SOD2 Hyperacetylation in Vascular Oxidative Stress and Hypertension
2017 · Anna E. Dikalova, Hana A. Itani, et al. · Circulation Research · 316
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The biochemistry of selenium and the glutathione system
2001 · Gavin E. Arteel, Helmut Sies · Environmental Toxicology and Pharmacology · 314
Protection against peroxynitrite
1999 · Gavin E. Arteel, Karlis Briviba, et al. · FEBS Letters · 305
Glutathione Peroxidase-Catalase Cooperativity Is Required for Resistance to Hydrogen Peroxide by Mature Rat Oligodendrocytes
2004 · Olivier Baud, Amanda E. Greene, et al. · Journal of Neuroscience · 292
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Glutathione Peroxidase (GPx)-like Antioxidant Activity of the Organoselenium Drug Ebselen: Unexpected Complications with Thiol Exchange Reactions
2005 · Bani Kanta Sarma, G. Mugesh · Journal of the American Chemical Society · 291
Antioxidants in disease mechanisms and therapy
1997 · Helmut Sies · 289
Works count: 2,067
Citation count: 85,070
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