Keyword

EF24

Description: EF24 is a synthetic curcumin analog studied as a bioactive compound in cancer and other biomedical research.

Primary topic: Curcumin's Biomedical Applications (46%)

OpenAlex ID: keywords/ef24

Hypoxia-mediated sorafenib resistance can be overcome by EF24 through Von Hippel-Lindau tumor suppressor-dependent HIF-1α inhibition in hepatocellular carcinoma

2013 · Yingjian Liang, Tongsen Zheng, et al. · Hepatology · 289

Inhibition of the NF-κB signaling pathway by the curcumin analog, 3,5-Bis(2-pyridinylmethylidene)-4-piperidone (EF31): Anti-inflammatory and anti-cancer properties

2011 · Anlys Olivera, Terry W. Moore, et al. · International Immunopharmacology · 229

EF24, a novel synthetic curcumin analog, induces apoptosis in cancer cells via a redox-dependent mechanism

2005 · Brian K. Adams, Jiyang Cai, et al. · Anti-Cancer Drugs · 202

EF24 induces ferroptosis in osteosarcoma cells through HMOX1

2021 · Haiyingjie Lin, Xiaoting Chen, et al. · Biomedicine & Pharmacotherapy · 176

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The curcumin analog EF24 is a novel senolytic agent

2019 · Wen Li, Yonghan He, et al. · Aging · 164

Inhibition of IκB Kinase-Nuclear Factor-κB Signaling Pathway by 3,5-Bis(2-flurobenzylidene)piperidin-4-one (EF24), a Novel Monoketone Analog of Curcumin

2008 · Andrea L. Kasinski, Yuhong Du, et al. · Molecular Pharmacology · 159

Diphenyl Difluoroketone: A Curcumin Derivative with Potent In vivo Anticancer Activity

2008 · Dharmalingam Subramaniam, Randal May, et al. · Cancer Research · 149

The Curcumin Analog EF24 Targets NF-κB and miRNA-21, and Has Potent Anticancer Activity In Vitro and In Vivo

2013 · Chuan He Yang, Junming Yue, et al. · PLoS ONE · 144

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EF24 Induces G2/M Arrest and Apoptosis in Cisplatin-resistant Human Ovarian Cancer Cells by Increasing PTEN Expression

2007 · Karuppaiyah Selvendiran, Liyue Tong, et al. · Journal of Biological Chemistry · 136

EF24, a novel curcumin analog, disrupts the microtubule cytoskeleton and inhibits HIF-1

2008 · Shala L. Thomas, Diansheng Zhong, et al. · Cell Cycle · 114

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Bioactivities of EF24, a Novel Curcumin Analog: A Review

2018 · Yonghan He, Wen Li, et al. · Frontiers in Oncology · 91

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MicroRNA-33b, upregulated by EF24, a curcumin analog, suppresses the epithelial-to-mesenchymal transition (EMT) and migratory potential of melanoma cells by targeting HMGA2

2015 · Pu Zhang, Huiyuan Bai, et al. · Toxicology Letters · 89

Synergistic antitumor activity of rapamycin and EF24 via increasing ROS for the treatment of gastric cancer

2016 · Weiqian Chen, Peng Zou, et al. · Redox Biology · 85

Synthesis of EF24−Tripeptide Chloromethyl Ketone: A Novel Curcumin-Related Anticancer Drug Delivery System

2006 · Aiming Sun, Mamoru Shoji, et al. · Journal of Medicinal Chemistry · 80

Curcumin analog EF24 induces apoptosis via ROS-dependent mitochondrial dysfunction in human colorectal cancer cells

2016 · Guodong He, Chen Feng, et al. · Cancer Chemotherapy and Pharmacology · 75

Curcumin and treatment of melanoma: The potential role of microRNAs

2017 · Diana Lelli, Claudio Pedone, et al. · Biomedicine & Pharmacotherapy · 66

In Vivo and In Vitro Suppression of Hepatocellular Carcinoma by EF24, a Curcumin Analog

2012 · Haitao Liu, Yingjian Liang, et al. · PLoS ONE · 57

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EF24 inhibits tumor growth and metastasis via suppressing NF-kappaB dependent pathways in human cholangiocarcinoma

2016 · Da-long Yin, Ying-jian Liang, et al. · Scientific Reports · 54

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A liposomal formulation of the synthetic curcumin analog EF24 (Lipo-EF24) inhibits pancreatic cancer progression: towards future combination therapies

2016 · Savita Bisht, Martin Schlesinger, et al. · Journal of Nanobiotechnology · 52

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EF24 induces ROS-mediated apoptosis via targeting thioredoxin reductase 1 in gastric cancer cells

2016 · Peng Zou, Yiqun Xia, et al. · Oncotarget · 52

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Multiple Anticancer Activities of EF24, a Novel Curcumin Analog, on Human Ovarian Carcinoma Cells

2010 · Xin Tan, Neil Sidell, et al. · Reproductive Sciences · 51

Activation of the p38 pathway by a novel monoketone curcumin analog, EF24, suggests a potential combination strategy

2010 · Shala L. Thomas, Jing Zhao, et al. · Biochemical Pharmacology · 46

Targeting tissue factor-expressing tumor angiogenesis and tumors with EF24 conjugated to factor VIIa

2008 · Mamoru Shoji, Aiming Sun, et al. · Journal of drug targeting · 44

Curcumin analogue EF24 prevents alveolar epithelial cell senescence to ameliorate idiopathic pulmonary fibrosis via activation of PTEN

2024 · Yanghuan Zhang, Jiahua Liu, et al. · Phytomedicine · 38

Therapeutic role of EF 24 targeting glucose transporter 1‐mediated metabolism and metastasis in ovarian cancer cells

2013 · Dandan Zhang, Yan Wang, et al. · Cancer Science · 38

Works count: 121

Citation count: 3,467