Keyword

eIF2α

Description: eIF2α is the alpha subunit of eukaryotic translation initiation factor 2, a protein involved in initiating protein synthesis and regulating cellular stress responses.

Primary topic: Endoplasmic Reticulum Stress and Disease (29%)

Wikidata ID: wiki/Q17916080

OpenAlex ID: keywords/eif2alpha

Endoplasmic reticulum stress in liver disease

2010 · Harmeet Malhi, Randal J. Kaufman · Journal of Hepatology · 1,177

Cell death induced by endoplasmic reticulum stress

2015 · Raffaella Iurlaro, Cristina Muñoz‐Pinedo · FEBS Journal · 1,065

Saturated fatty acids induce endoplasmic reticulum stress and apoptosis independently of ceramide in liver cells

2006 · Yuren Wei, Dong Wang, et al. · American Journal of Physiology-Endocrinology and Metabolism · 736

Inhibition of the Interferon- Inducible Protein Kinase PKR by HCV E2 Protein

1999 · Deborah R. Taylor, Stephanie T. Shi, et al. · Science · 733

ER stress‐regulated translation increases tolerance to extreme hypoxia and promotes tumor growth

2005 · Meixia Bi, Christine Naczki, et al. · The EMBO Journal · 730

The GCN2‐ATF4 pathway is critical for tumour cell survival and proliferation in response to nutrient deprivation

2010 · Jiangbin Ye, Monika Kumanova, et al. · The EMBO Journal · 703

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Hypoxia-Induced Energy Stress Regulates mRNA Translation and Cell Growth

2006 · Liping Liu, Timothy P. Cash, et al. · Molecular Cell · 605

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The Unfolded Protein Response Is Activated in Pretangle Neurons in Alzheimer's Disease Hippocampus

2009 · Jeroen J.M. Hoozemans, Elise S. van Haastert, et al. · American Journal Of Pathology · 600

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UPR Pathways Combine to Prevent Hepatic Steatosis Caused by ER Stress-Mediated Suppression of Transcriptional Master Regulators

2008 · D. Thomas Rutkowski, Jun Wu, et al. · Developmental Cell · 580

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Chronic Palmitate But Not Oleate Exposure Induces Endoplasmic Reticulum Stress, Which May Contribute to INS-1 Pancreatic β-Cell Apoptosis

2006 · Elizabeth Karaskov, Cameron Scott, et al. · Endocrinology · 573

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Oxytosis: A Novel Form of Programmed Cell Death

2001 · Bentham Science Publisher Shirlee Tan, Bentham Science Publisher David Schubert, et al. · Current Topics in Medicinal Chemistry · 522

Angiogenin-induced tRNA-derived Stress-induced RNAs Promote Stress-induced Stress Granule Assembly

2010 · Mohamed M. Emara, Pavel Ivanov, et al. · Journal of Biological Chemistry · 500

Endoplasmic Reticulum Stress Is Reduced in Tissues of Obese Subjects After Weight Loss

2008 · Margaret F. Gregor, Ling Yang, et al. · Diabetes · 488

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Orally Administered Leucine Stimulates Protein Synthesis in Skeletal Muscle of Postabsorptive Rats in Association with Increased eIF4F Formation

2000 · Joshua C. Anthony, Tracy Gautsch Anthony, et al. · Journal of Nutrition · 469

Translational control of C/EBPα and C/EBPβ isoform expression

2000 · Cor F. Calkhoven, Christine Müller, et al. · Genes & Development · 426

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Heme‐regulated eIF2α kinase (HRI) is required for translational regulation and survival of erythroid precursors in iron deficiency

2001 · An‐Ping Han, Channing Yu, et al. · The EMBO Journal · 398

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Translational control of C/EBP alpha and C/EBP beta isoform expression

2000 · Cornelis F. Calkhoven, Christopher G. Mueller, et al. · University of Groningen research database (University of Groningen / Centre for Information Technology) · 398

Higher-Order Substrate Recognition of eIF2α by the RNA-Dependent Protein Kinase PKR

2005 · Arvin C. Dar, Thomas E. Dever, et al. · Cell · 386

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Amino Acid Starvation Induced by Invasive Bacterial Pathogens Triggers an Innate Host Defense Program

2012 · Ivan Tattoli, Matthew T. Sorbara, et al. · Cell Host & Microbe · 367

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The PERK/eIF2α/ATF4 module of the UPR in hypoxia resistance and tumor growth

2006 · Diane R. Fels, Constantinos Koumenis · Cancer Biology & Therapy · 347

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ER and Nutrient Stress Promote Assembly of Respiratory Chain Supercomplexes through the PERK-eIF2α Axis

2019 · Eduardo Balsa, Meghan S. Soustek, et al. · Molecular Cell · 326

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