Keyword

EKLF

Description: EKLF, or erythroid Krüppel-like factor, is a transcription factor encoded by KLF1 that regulates globin gene expression and erythroid development.

Primary topic: Kruppel-like factors research (50%)

Wikidata ID: wiki/Q18035587

OpenAlex ID: keywords/eklf

A Novel, Erythroid Cell-Specific Murine Transcription Factor that Binds to the CACCC Element and is Related to the Krüppel Family of Nuclear Proteins†

1993 · I J Miller, J J Bieker · Molecular and Cellular Biology · 726

Lethal β-thalassaemia in mice lacking the erythroid CACCC-transcription factor EKLF

1995 · Andrew C. Parkins, Arlene H. Sharpe, et al. · Nature · 603

Transcriptional regulation of erythropoiesis: an affair involving multiple partners

2002 · Alan B Cantor, Stuart H Orkin · Oncogene · 594

Defective haematopoiesis in fetal liver resulting from inactivation of the EKLF gene

1995 · Beatriz Nuez, Dave Michalovich, et al. · Nature · 551

Functional Synergy and Physical Interactions of the Erythroid Transcription Factor GATA-1 with the Krüppel Family Proteins Sp1 and EKLF

1995 · Menie Merika, Stuart H. Orkin · Molecular and Cellular Biology · 462

The active spatial organization of the β-globin locus requires the transcription factor EKLF

2004 · Roy Drissen, Robert-Jan Palstra, et al. · Genes & Development · 352

PDF

Acetylation and modulation of erythroid Krüppel-like factor (EKLF) activity by interaction with histone acetyltransferases

1998 · Wenjun Zhang, James J. Bieker · Proceedings of the National Academy of Sciences · 342

1998 · Jennifer A Armstrong, James J Bieker, et al. · Cell · 303

PDF

Mammalian Krüppel-like transcription factors: more than just a pretty finger

1999 · Jeremy Turner, Merlin Crossley · Trends in Biochemical Sciences · 294

Isolation of a Gene Encoding a Functional Zinc Finger Protein Homologous to Erythroid Krüppel-Like Factor: Identification of a New Multigene Family

1995 · Kathleen P. Anderson, Christine B. Kern, et al. · Molecular and Cellular Biology · 262

PDF

Use of developmental marker genes to define temporal and spatial patterns of differentiation during embryoid body formation

1999 · Amy Leahy, Jing-Wei Xiong, et al. · Journal of Experimental Zoology · 246

Isolation and Characterization of the cDNA Encoding BKLF/TEF-2, a Major CACCC-Box-Binding Protein in Erythroid Cells and Selected Other Cells

1996 · Merlin Crossley, Emma Whitelaw, et al. · Molecular and Cellular Biology · 222

A global role for EKLF in definitive and primitive erythropoiesis

2005 · Denise Hodge, Elise Coghill, et al. · Blood · 209

The role of EKLF in human beta-globin gene competition.

1996 · M Wijgerde, J Gribnau, et al. · Genes & Development · 203

PDF

Role of Erythroid Kruppel-like Factor in Human γ- to β-Globin Gene Switching

1995 · David Donze, Tim M. Townes, et al. · Journal of Biological Chemistry · 198

Human EZF, a Krüppel-like Zinc Finger Protein, Is Expressed in Vascular Endothelial Cells and Contains Transcriptional Activation and Repression Domains

1998 · Shaw-Fang Yet, Megan M. McA'Nulty, et al. · Journal of Biological Chemistry · 188

Analyses of beta-thalassemia mutant DNA interactions with erythroid Krüppel-like factor (EKLF), an erythroid cell-specific transcription factor.

1994 · W.C. Feng, C.M. Southwood, et al. · Journal of Biological Chemistry · 186

Site-Specific Acetylation by p300 or CREB Binding Protein Regulates Erythroid Krüppel-Like Factor Transcriptional Activity via Its Interaction with the SWI-SNF Complex

2001 · Wenjun Zhang, Shilpa Kadam, et al. · Molecular and Cellular Biology · 182

New insights into erythropoiesis

2002 · Mark J. Koury, Stephen T. Sawyer, et al. · Current Opinion in Hematology · 177

Genetic regulatory networks programming hematopoietic stem cells and erythroid lineage specification

2006 · Gemma Swiers, Roger Patient, et al. · Developmental Biology · 168

PDF

The Erythroid Phenotype of EKLF-Null Mice: Defects in Hemoglobin Metabolism and Membrane Stability

2005 · Roy Drissen, Marieke von Lindern, et al. · Molecular and Cellular Biology · 168

Mutations in EKLF/KLF1 form the molecular basis of the rare blood group In(Lu) phenotype

2008 · Belinda K. Singleton, Nicholas M. Burton, et al. · Blood · 163

Mechanisms of developmental control of transcription in the murine α- and β-globin loci

1999 · Tolleiv Trimborn, Joost Gribnau, et al. · Genes & Development · 145

PDF

Functional Cross-Antagonism between Transcription Factors FLI-1 and EKLF

2003 · Joëlle Starck, Nathalie Cohet, et al. · Molecular and Cellular Biology · 144

Novel role for EKLF in megakaryocyte lineage commitment

2007 · Pilar Frontelo, Deepa Manwani, et al. · Blood · 142

PDF

Works count: 397

Citation count: 15,280