Keyword

emphysema

Description: Emphysema is a chronic lung disease involving damage to alveolar walls and abnormal enlargement of air spaces, often associated with chronic obstructive pulmonary disease.

Primary topic: Chronic Obstructive Pulmonary Disease (COPD) Research (49%)

Wikidata ID: wiki/Q188605

OpenAlex ID: keywords/emphysema

Mutation of the mouse klotho gene leads to a syndrome resembling ageing.

1997 · M Kuro-o, Y Matsumura, et al. · PubMed · 66,481

Mutation of the mouse klotho gene leads to a syndrome resembling ageing

1997 · Makoto Kuro-o, Yutaka Matsumura, et al. · Nature · 3,833

Global burden of COPD: systematic review and meta-analysis

2006 · R. J. Halbert, J. L. Natoli, et al. · European Respiratory Journal · 1,500

Requirement for Macrophage Elastase for Cigarette Smoke-Induced Emphysema in Mice

1997 · R. Dean Hautamaki, Dale K. Kobayashi, et al. · Science · 1,470

Deep learning for chest radiograph diagnosis: A retrospective comparison of the CheXNeXt algorithm to practicing radiologists

2018 · Pranav Rajpurkar, Jeremy Irvin, et al. · PLoS Medicine · 1,447

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Free-Radical Chemistry of Cigarette Smoke and Its Toxicological Implications

1985 · D F Church, W A Pryor · Environmental Health Perspectives · 1,442

Chronic obstructive pulmonary disease: molecular and cellularmechanisms

2003 · P.J. Barnes, S.D. Shapiro, et al. · European Respiratory Journal · 1,440

Probability of Cancer in Pulmonary Nodules Detected on First Screening CT

2013 · Annette McWilliams, Martin C. Tammemagi, et al. · New England Journal of Medicine · 1,417

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Dysregulation of TGF-β activation contributes to pathogenesis in Marfan syndrome

2003 · Enid R. Neptune, Pamela A. Frischmeyer, et al. · Nature Genetics · 1,406

Site and Nature of Airway Obstruction in Chronic Obstructive Lung Disease

1968 · James C. Hogg, Peter T. Macklem, et al. · New England Journal of Medicine · 1,402

Genetic Epidemiology of COPD (COPDGene) Study Design

2010 · Elizabeth A. Regan, John E. Hokanson, et al. · COPD Journal of Chronic Obstructive Pulmonary Disease · 1,313

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Pathophysiology of airflow limitation in chronic obstructive pulmonary disease

2004 · James C Hogg · The Lancet · 1,298

Chronic Obstructive Pulmonary Disease Surveillance—United States, 1971–2000

2002 · David M Mannino, David M Homa, et al. · Respiratory Care · 1,294

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Small-Airway Obstruction and Emphysema in Chronic Obstructive Pulmonary Disease

2011 · John E. McDonough, Ren Yuan, et al. · New England Journal of Medicine · 1,211

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Histoplasmosis: a Clinical and Laboratory Update

2007 · Carol A. Kauffman · Clinical Microbiology Reviews · 1,204

Characterisation of COPD heterogeneity in the ECLIPSE cohort

2010 · the Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) investigators, Alvar Agusti, et al. · Respiratory Research · 1,161

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Heme Oxygenase-1: Function, Regulation, and Implication of a Novel Stress-Inducible Protein in Oxidant-Induced Lung Injury

1996 · A M Choi, J Alam · American Journal of Respiratory Cell and Molecular Biology · 1,125

Inhibition of VEGF receptors causes lung cell apoptosis and emphysema

2000 · Yasunori Kasahara, Rubin M. Tuder, et al. · Journal of Clinical Investigation · 1,112

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Chronic Obstructive Pulmonary Disease

2000 · Peter J. Barnes · New England Journal of Medicine · 1,080

Phagocytes and oxidative stress

2000 · Bernard M. Babior · The American Journal of Medicine · 1,062

Systemic effects of chronic obstructive pulmonary disease

2003 · A.G.N. Agustí, A. Noguera, et al. · European Respiratory Journal · 1,045

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Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke–induced emphysema in mice

2004 · Tirumalai Rangasamy, Chung Y. Cho, et al. · Journal of Clinical Investigation · 992

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Changes in Forced Expiratory Volume in 1 Second over Time in COPD

2011 · Jørgen Vestbo, Lisa D. Edwards, et al. · New England Journal of Medicine · 963

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Malignant Interstitial Emphysema of the Lungs and Mediastinum as an Important Occult Complication in Many Respiratory Diseases and Other Conditions

1944 · MADGE THURLOW MACKLIN, CHARLES C. MACKLIN · Medicine · 962

Interleukin-18 and IL-18 Binding Protein

2013 · Charles A. Dinarello, Daniela Novick, et al. · Frontiers in Immunology · 939

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Works count: 38,590

Citation count: 710,300